Patents by Inventor Joël Aerts

Joël Aerts has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the preparation of reactive [18] F fluoride
    Patent number: 8641903
    Abstract: The present invention is related to a method to obtain reactive [18F] fluorides in an organic medium suitable for radiolabelling without any azeotropic evaporation step, by the use of a solid phase extraction column containing a modified non-ionic solid support.
    Type: Grant
    Filed: April 22, 2008
    Date of Patent: February 4, 2014
    Assignees: Trasis S.A., Universite de Liège
    Inventors: Samuel Voccia, Joël Aerts, Christian Lemaire, André Luxen, Jean-Luc Morelle, Gauthier Philippart
  • Method for the direct elution of reactive 18F fluoride from an anion exchange resin in an organic medium suitable for radiolabelling without any evaporation step by the use of strong organic bases
    Patent number: 8491790
    Abstract: A method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step wherein the eluting solution is a organic solution having a water content <3%. The solution contains at least: an organic solvent suitable for the subsequent radiolabelling reaction; a first compound (A) which is a molecule containing at least one acidic hydrogen and a second compound (B) which is an organic base sufficiently strong to be able to tear off the acidic hydrogen of the first compound (A) in an acid-base reaction leading to the formation of an organic salt (S).
    Type: Grant
    Filed: July 1, 2008
    Date of Patent: July 23, 2013
    Assignees: Trasis S.A., Universite de Liège
    Inventors: Christian Lemaire, Samuel Voccia, Joël Aerts, André Luxen, Jean-Luc Morelle, Gauthier Philipart
  • Method for the elution of 18F fluoride trapped on an anion-exchange phase in a form suitable for efficient radiolabeling without any evaporation step
    Patent number: 8366934
    Abstract: A method extracts out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step. The eluting solution is a low water content, preferably <3% water, organic solution containing at least: a first compound (A) which is a tertiary alcohol-function bearing molecule, a second compound (B) which is a phase transfer agent suitable for radiolabeling and which is necessary to the anion exchange process.
    Type: Grant
    Filed: February 19, 2008
    Date of Patent: February 5, 2013
    Assignees: Trasis S.A., Universite de liege
    Inventors: Joel Aerts, Christian LeMaire, Steve Lignon, André Luxen, Jean-Luc Morelle, Gauthier Philippart, Samuel Voccia
  • METHOD FOR THE ELUTION OF 18F FLUORIDE TRAPPED ON AN ANION-EXCHANGE PHASE IN A FORM SUITABLE FOR EFFICIENT RADIOLABELING WITHOUT ANY EVAPORATION STEP
    Publication number: 20110006011
    Abstract: A method extracts out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step. The eluting solution is a low water content, preferably <3% water, organic solution containing at least: a first compound (A) which is a tertiary alcohol-function bearing molecule, a second compound (B) which is a phase transfer agent suitable for radiolabeling and which is necessary to the anion exchange process.
    Type: Application
    Filed: February 19, 2008
    Publication date: January 13, 2011
    Applicants: TRASIS S.A., UNIVERSITE DE LIEGE
    Inventors: Joel Aerts, Christian Lemaire, Steve Lignon, Andre Luxen, Jean-Luc Morelle, Gauthier Philippart, Samuel Voccia
  • METHOD FOR THE PREPARATION OF REACTIVE [18] F FLUORIDE
    Publication number: 20100243972
    Abstract: The present invention is related to a method to obtain reactive [18F] fluorides in an organic medium suitable for radiolabelling without any azeotropic evaporation step, by the use of a solid phase extraction column containing a modified non-ionic solid support.
    Type: Application
    Filed: April 22, 2008
    Publication date: September 30, 2010
    Applicants: Trasis S.A., Universite de Liege
    Inventors: Samuel Voccia, Joél Aerts, Christian Lemaire, André Luxen, Jean-Luc Morelle, Gauthier Philippart
  • METHOD FOR THE DIRECT ELUTION OF REACTIVE 18F FLUORIDE FROM AN ANION EXCHANGE RESIN IN AN ORGANIC MEDIUM SUITABLE FOR RADIOLABELLING WITHOUT ANY EVAPORATION STEP BY THE USE OF STRONG ORGANIC BASES
    Publication number: 20100196254
    Abstract: A method to extract out of an aqueous solution, concentrate and/or reformulate [18F] fluorides without any evaporation step wherein the eluting solution is a organic solution having a water content <3%. The solution contains at least: an organic solvent suitable for the subsequent radiolabelling reaction; a first compound (A) which is a molecule containing at least one acidic hydrogen and a second compound (B) which is an organic base sufficiently strong to be able to tear off the acidic hydrogen of the first compound (A) in an acid-base reaction leading to the formation of an organic salt (S).
    Type: Application
    Filed: July 1, 2008
    Publication date: August 5, 2010
    Applicants: TRASIS S.A., UNIVERSITE DE LIEGE
    Inventors: Christian Lemaire, Samuel Voccia, Joël Aerts, André Luxen, Jean-Luc Morelle, Gauthier Philipart