Patents by Inventor Joël Lemaoult

Joël Lemaoult has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL T CELLS AND THE USES THEREOF
    Publication number: 20230349902
    Abstract: The invention relates to a new population of T cells, expressing the following biomarkers: CD3, CD4, CD57 and ILT2, as well to the uses thereof, such as for diagnosis, prognosis or treatment of various immune pathologies or responses, including graft rejection, autoimmune diseases, infectious diseases or cancers.
    Type: Application
    Filed: July 26, 2021
    Publication date: November 2, 2023
    Inventors: NATHALIE ROUAS-FREISS, JOEL LEMAOULT, EDGARDO CAROSELLA, OLIVIER BRUGIERE, DOMITILLE MOUREN
  • METHODS FOR THE MONITORING AND PROGNOSIS OF A CANCER
    Publication number: 20200158715
    Abstract: The present invention relates to methods for prognosis and monitoring of a cancer, preferably bladder cancer, by measuring the proportion of CD8+ T Lymphocytes expressing ILT-2 and the plasma level of soluble HLA-G. The invention also relates to anti HLA-G antibodies for use for treating a cancer in which tumor cells express HLA-G, preferably bladder cancer.
    Type: Application
    Filed: January 28, 2020
    Publication date: May 21, 2020
    Inventors: François Desgrandchamps, Edgardo Delfino Carosella, Joël Lemaoult
  • Methods for the monitoring and prognosis of a cancer
    Patent number: 10545136
    Abstract: The present invention relates to methods for prognosis and monitoring of a cancer, preferably bladder cancer, by measuring the proportion of CD8+ T Lymphocytes expressing ILT-2 and the plasma level of soluble HLA-G. The invention also relates to anti HLA-G antibodies for use for treating a cancer in which tumor cells express HLA-G, preferably bladder cancer.
    Type: Grant
    Filed: October 16, 2015
    Date of Patent: January 28, 2020
    Assignees: ASSISTANCE PUBLIQUE HOPITAUX DE PARIS, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, Université Paris Diderot—Paris 7
    Inventors: François Desgrandchamps, Edgardo Delfino Carosella, Joël Lemaoult
  • METHODS FOR THE MONITORING AND PROGNOSIS OF A CANCER
    Publication number: 20170219561
    Abstract: The present invention relates to methods for prognosis and monitoring of a cancer, preferably bladder cancer, by measuring the proportion of CD8+ T Lymphocytes expressing ILT-2 and the plasma level of soluble HLA-G. The invention also relates to anti HLA-G antibodies for use for treating a cancer in which tumor cells express HLA-G, preferably bladder cancer.
    Type: Application
    Filed: October 16, 2015
    Publication date: August 3, 2017
    Inventors: François Desgrandchamps, Edgardo Delfino Carosella, Joël Lemaoult
  • HLA-G POLYPEPTIDES AND PHARMACEUTICAL USES THEREOF
    Publication number: 20110274711
    Abstract: The present invention relates to novel proteins and pharmaceutical uses thereof The invention more specifically relates to novel proteins comprising the sequence of an HLA-5 antigen fused to the sequence of a b2 microglobulin. The invention also relates to methods of producing such polypeptides, pharmaceutical compositions comprising the same, as well as their uses for treating various diseases including organ/tissue rejection.
    Type: Application
    Filed: November 4, 2009
    Publication date: November 10, 2011
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, HLA-G TECHNOLOGIES
    Inventors: Benoit Favier, Edgardo D. Carosella, Joël Lemaoult
  • HLA-G PROTEINS AND PHARMACEUTICAL USES THEREOF
    Publication number: 20110268737
    Abstract: The present invention relates to novel proteins and pharmaceutical uses thereof. The invention more specifically relates to novel fusion proteins comprising a domain of an HLA-G antigen fused to an Fc domain of an immunoglobulin. The invention also relates to methods of producing such polypeptides, pharmaceutical compositions comprising the same, as well as their uses for treating various diseases including organ/tissue rejection.
    Type: Application
    Filed: November 4, 2009
    Publication date: November 3, 2011
    Applicants: COMMISSARIAT A L'ENEGRIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, HLA-G TECHNOLOGIES
    Inventors: Benoit Favier, Edgardo D. Carosella, Joël Lemaoult