Patents by Inventor Joël Nargeot

Joël Nargeot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of apoptosis and uses thereof
    Patent number: 9814758
    Abstract: The invention relates to fragments of the Death-Domain Associated protein (DAXX protein) and of the Fas-Associated Death Domain protein (FADD protein) that inhibit cell apoptosis, in particular cell apoptosis mediated by the Fas receptor. The invention also relates to derivatives of said anti-apoptotic fragments, conjugates comprising said fragments, pharmaceutical compositions comprising said fragments, and to the medical applications of said fragments, derivatives, conjugates, and pharmaceutical compositions thereof in the treatment or prevention of diseases and conditions associated with apoptosis.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: November 14, 2017
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE MONTPELLIER 2-SCIENCES ET TECHNIQUE, UNIVERSITE DE MONTPELLIER 1
    Inventors: Stéphanie Barrere, Joël Nargeot, Bernard Lebleu, Prisca Boisguerin, Christophe Piot
  • Identification of novel antagonist toxins of T-type calcium channel for analgesic purposes
    Patent number: 8664179
    Abstract: A peptide with the following sequence YCQKFLWTCDSERPCCEGLVCRLWCKIN (SEQ ID NO 1) or a derivative thereof, and nucleic acids coding for the peptide having the sequence (SEQ ID NO 1). Also the use of this peptide as an antagonist and/or reverse agonist of T-type calcium channels. A use of the peptide for preparing a drug, in particular an analgesic one.
    Type: Grant
    Filed: January 15, 2010
    Date of Patent: March 4, 2014
    Assignees: Centre National de la Recherche Scientifique (CNRS), Universite de Nice Sophia Antipolis
    Inventors: Emmanuel Bourinet, Pierre Escoubas, Fabrice Marger, Joel Nargeot, Michel Lazdunski
  • Inhibitors of Apoptosis and Uses Thereof
    Publication number: 20130288979
    Abstract: The invention relates to fragments of the DAXX and FADD proteins that inhibit cell apoptosis, in particular cell apoptosis mediated by the Fas receptor. The invention also relates to derivatives of said anti-apoptotic fragments, conjugates comprising said fragments, pharmaceutical compositions comprising said fragments, and to the medical applications of said fragments, derivatives, conjugates, and pharmaceutical compositions thereof in the treatment or prevention of diseases and conditions associated with apoptosis.
    Type: Application
    Filed: November 17, 2011
    Publication date: October 31, 2013
    Applicants: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS, UNIVERSITE DE MONTPELLIER 1, UNIVERSITE MONTPELLIER 2-SCIENCES ET TECHNIQUE
    Inventors: Stéphanie Barrere, Joël Nargeot, Bernard Lebleu, Prisca Boisguerin, Christophe Piot
  • IDENTIFICATION OF NOVEL ANTAGONIST TOXINS OF T-TYPE CALCIUM CHANNEL FOR ANALGESIC PURPOSES
    Publication number: 20120040909
    Abstract: A peptide with the following sequence YCQKFLWTCDSERPCCEGLVCRLWCKIN (SEQ ID NO 1) or a derivative thereof, and nucleic acids coding for the peptide having the sequence (SEQ ID NO 1). Also the use of this peptide as an antagonist and/or reverse agonist of T-type calcium channels. A use of the peptide for preparing a drug, in particular an analgesic one.
    Type: Application
    Filed: January 15, 2010
    Publication date: February 16, 2012
    Applicants: UNIVERSITE DE NICE SOPHIA ANTIPOLIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
    Inventors: Emmanuel Bourinet, Pierre Escoubas, Fabrice Marger, Joel Nargeot, Michel Lazdunski