Patents by Inventor João Pedro Silva Serra

João Pedro Silva Serra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antibacterial quinolines
    Publication number: 20230106913
    Abstract: The present disclosure relates to 6-substituted quinoline-2-piperidine derivatives for use in the treatment and/or prevention of tuberculosis.
    Type: Application
    Filed: December 28, 2020
    Publication date: April 6, 2023
    Inventors: Augusto Eugénio PARDAL FILIPE, Carla Patrícia DA COSTA PEREIRA ROSA, Ana Vanessa CORDEIRO SIMÕES, João Carlos RAMOS DAMIL, João Pedro SILVA SERRA, Ana Lúcia ALMEIDA FERREIRA, Rita Isabel GOMES NEVES, Sara Alexandra MARQUES HOMEM E SOUSA DOS SANTOS
  • COMPRESSED MACITENTAN COMPOSITIONS, METHODS AND USES THEREOF
    Publication number: 20220249381
    Abstract: The present disclosure also relates to compressed compositions comprising a therapeutically effective amount of macitentan, a sugar alcohol diluent and a surfactant. It also relates to the process of obtaining said compressed compositions, oral pharmaceutical compositions comprising them, and their use in the treatment of pulmonary arterial hypertension. The present disclosure also relates to solid oral pharmaceutical compositions comprising a therapeutically effective amount of macitentan that simultaneously display improved stability properties and adequate dissolution profiles represents an unmet need in the field of pharmaceutical macitentan formulation.
    Type: Application
    Filed: July 3, 2020
    Publication date: August 11, 2022
    Inventors: João Pedro SILVA SERRA, Ricardo José Camilo FERREIRA PEREIRA
  • Processes for the preparation of pharmaceutically acceptable salts of (R)-Pirlindole and (S)-Pirlindole
    Patent number: 11008328
    Abstract: The present invention relates to an improved process for the preparation of Pirlindole enantiomers, or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 18, 2021
    Assignee: TECNIMEDE, SOCIEDADE TÉCNICO-MEDICINAL, SA
    Inventors: Carla Patrícia Da Costa Pereira Rosa, João Carlos Ramos Damil, Ana Vanessa Cordeiro Simões, João Pedro Silva Serra
  • Processes for the preparation of pharmaceutically acceptable salts of (R)-Pirlindole and (S)-Pirlindole
    Patent number: 11008327
    Abstract: The present disclosure relates to an improved process for the synthesis of piperazine ring, particularly for the preparation of heterocyclic compounds useful as intermediates in the synthesis of pyrazinocarbazoles such as the antidepressant Pirlindole. The process described is useful to prepare Pirlindole enantiomers, or a pharmaceutically accepted salt thereof.
    Type: Grant
    Filed: April 20, 2018
    Date of Patent: May 18, 2021
    Assignee: TECNIMEDE, SOCIEDADE TÉCNICO-MEDICINAL, SA
    Inventors: Carla Patrícia Da Costa Pereira Rosa, João Carlos Ramos Damil, Ana Vanessa Cordeiro Simões, João Pedro Silva Serra
  • PROCESS FOR THE PREPARATION OF PIRLINDOLE ENANTIOMERS AND ITS SALTS
    Publication number: 20200190098
    Abstract: The present invention relates to an improved process for the preparation of Pirlindole enantiomers, or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: April 20, 2018
    Publication date: June 18, 2020
    Inventors: Carla Patrícia DA COSTA PEREIRA ROSA, João Carlos RAMOS DAMIL, Ana Vanessa CORDEIRO SIMÕES, João Pedro SILVA SERRA
  • PROCESS FOR THE PREPARATION OF PIPERAZINE RING FOR THE SYNTHESIS OF PYRAZINOCARBAZOLE DERIVATIVES
    Publication number: 20200131186
    Abstract: The present disclosure relates to an improved process for the synthesis of piperazine ring, particularly for the preparation of heterocyclic compounds useful as intermediates in the synthesis of pyrazinocarbazoles such as the antidepressant Pirlindole. The process described is useful to prepare Pirlindole enantiomers, or a pharmaceutically accepted salt thereof.
    Type: Application
    Filed: April 20, 2018
    Publication date: April 30, 2020
    Inventors: Carla Patrícia DA COSTA PEREIRA ROSA, João Carlos RAMOS DAMIL, Ana Vanessa CORDEIRO SIMÕES, João Pedro SILVA SERRA
  • SOLID COMPOSITION FOR ORAL ADMINISTRATION CONTAINING IBANDRONIC ACID OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF AND VITAMIN D
    Publication number: 20160106766
    Abstract: An improved solid pharmaceutical composition for oral administration comprising ibandronic acid or a pharmaceutically acceptable salt thereof, vitamin D and medium chain triglycerides or totally or partially hydrogenated oils which confer desirable physico-chemical properties to a solid formulation for oral administration suitable for the treatment of bone diseases and disorders of calcium metabolism.
    Type: Application
    Filed: May 30, 2014
    Publication date: April 21, 2016
    Applicant: TECNIMEDE SOCIEDADE TECNICO-MEDICINAL S.A.
    Inventors: Joao Pedro SILVA SERRA, Isabel Maria SOARES
  • METHOD AND COMPOSITION FOR PREPARING STABLE LIQUID FORMULATIONS OF PARACETAMOL
    Publication number: 20120245230
    Abstract: The present invention relates to stable liquid formulations of paracetamol for pharmaceutical use and to a method of preparation of stable paracetamol solutions.
    Type: Application
    Filed: December 10, 2009
    Publication date: September 27, 2012
    Applicant: TECNIMEDE-SOCIEDADE TECNICO- MEDICINAL, S.A.
    Inventors: Dina Stela Velez Ferreira, João Pedro Silva Serra, Nuno Miguel Araüjo Quintal