Patents by Inventor Joachim Bar

Joachim Bar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Secondary binding site of dipeptidyl peptidase IV (DP IV)
    Patent number: 7816325
    Abstract: The present application relates to the secondary binding site of dipeptidyl peptidase IV, its relationship amongst substrates and to the modulation of substrate specificity of dipeptidyl peptidase IV (DP IV, synonym: DPP IV, CD26, EC 3.4.14.5). The application relates further to compounds that bind to the secondary binding site of DP IV and their use to modulate the substrate specificity of DP IV; methods of treatment of various DP IV mediated disorders; and screening methods for the identification of secondary binding sites on DP IV and DP IV-like enzymes.
    Type: Grant
    Filed: June 29, 2006
    Date of Patent: October 19, 2010
    Assignee: OSI Pharmaceuticals, Inc.
    Inventors: Kerstin Kühn-Wache, Joachim Bär, Hans-Ulrich Demuth, Torsten Hoffmann, Ulrich Heiser, Wolfgang Brandt
  • Secondary binding site of dipeptidyl peptidase IV (DP IV)
    Publication number: 20060234940
    Abstract: The present application relates to the secondary binding site of dipeptidyl peptidase IV, its relationship amongst substrates and to the modulation of substrate specificity of dipeptidyl peptidase IV (DP IV, synonym: DPP IV, CD26, EC 3.4.14.5). The application relates further to compounds that bind to the secondary binding site of DP IV and their use to modulate the substrate specificity of DP IV; methods of treatment of various DP IV mediated disorders; and screening methods for the identification of secondary binding sites on DP IV and DP IV-like enzymes.
    Type: Application
    Filed: June 29, 2006
    Publication date: October 19, 2006
    Inventors: Kerstin Kuhn-Wache, Joachim Bar, Hans-Ulrich Demuth, Torsten Hofmann, Ulrich Heiser, Wolfgang Brandt
  • Secondary binding site of dipeptidyl peptidase IV (DPIV)
    Publication number: 20050176622
    Abstract: The present application relates to the secondary binding site of dipeptidyl peptidase IV, its relationship amongst substrates and to the modulation of substrate specificity of dipeptidyl peptidase IV (DP IV, synonym: DPP IV, CD26, EC 3.4.14.5). The application relates further to compounds that bind to the secondary binding site of DP IV and their use to modulate the substrate specificity of DP IV; methods of treatment of various DP IV mediated disorders; and screening methods for the identification of secondary binding sites on DP IV and DP IV-like enzymes.
    Type: Application
    Filed: September 18, 2003
    Publication date: August 11, 2005
    Inventors: Kerstin Kuhn-Wache, Joachim Bar, Hans-Ulrich Demuth, Torsten Hoffmann, Ulrich Heiser, Wolfgang Brandt