Patents by Inventor Joachim Brendel

Joachim Brendel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted benzoylguanidines, a process for their preparation, their use as medicament of diagnostic agent, and medicament comprising them
    Patent number: 5747541
    Abstract: The present invention relates to substituted benzoylguanidines, a process for their preparation, their use as medicament or diagnostic agent, and medicament comprising them.
    Type: Grant
    Filed: June 12, 1997
    Date of Patent: May 5, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Andreas Weichert, Joachim Brendel, Heinz-Werner Kleemann, Hans Jochen Lang, Jan-Robert Schwark, Udo Albus, Wolfgang Scholz
  • Substituted benzenedicarboxylic acid diguanides, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
    Patent number: 5731350
    Abstract: Benzenedicarboxylic acid diguanides of the formula I ##STR1## in which R(1) to R(5) have the meanings given in the claims, are useful antiarrhythmic pharmaceuticals having a cardioprotective component, even for the prevention of ischemically induced damage, in particular in the induction of ischemically induced cardiac arrhythmias. As a result of inhibition of the cellular Na.sup.+ /H.sup.+ exchange mechanism, they are used for the treatment of acute or chronic damage caused by ischemia. Moreover, they are distinguished by potent inhibitory action on the proliferation of cells. They are suitable for preventing the genesis of high blood pressure.
    Type: Grant
    Filed: November 7, 1996
    Date of Patent: March 24, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz-Werner Kleemann, Joachim Brendel, Jan-Robert Schwark, Andreas Weichert, Hans Jochen Lang, Udo Albus, Wolfgang Scholz
  • Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising them
    Patent number: 5708034
    Abstract: Substituted sulfonimidamides, processes for their preparation, their use as a medicament or diagnostic, and medicament comprising themSulfonimidamides of the formula I ##STR1## in which at least one of the three substituents R(1), R(2) and R(3) is a benzoylguanidine, and in which the other substituents have the meanings indicated in the claims, are outstandingly suitable as medicaments having action on the cardiovascular system; that is as antiarrhythmic pharmaceuticals having a cardioprotective component as well as for treating ischemically induced damage; also in operative interventions, such as organ transplantation.
    Type: Grant
    Filed: October 31, 1996
    Date of Patent: January 13, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinz-Werner Kleemann, Joachim Brendel, Jan-Robert Schwark, Andreas Weichert, Hans Jochen Lang, Udo Albus, Wolfgang Scholz
  • Pyrimidofuroxans, their preparation and their use
    Patent number: 5382585
    Abstract: The present invention relates to pyrimidofuroxans of the general formula I ##STR1## in which A denotes ##STR2## where in each case the nitrogen atom is bonded via the C-4 and the carbon atom via the C-3 of the furoxan ring and the R radicals are defined as indicated in Claim 1, processes for their preparation and their use for the control and prevention of disorders of the cardiovascular system, in particular for the control and prevention of angina pectoris, and for the treatment of erectile dysfunctions.
    Type: Grant
    Filed: May 25, 1993
    Date of Patent: January 17, 1995
    Assignee: Cassella AG
    Inventors: Joachim Brendel, Karl Schonafinger, Helmut Bohn
  • Fused 1,2,5-oxadiazole-2-oxides and their use
    Patent number: 5360812
    Abstract: The present invention relates to fused 1,2,5-oxadiazole-2-oxides of the general formula I ##STR1## in which A denotes ##STR2## and X, Y, Z as well as R.sup.1, R.sup.2, R.sup.3 and n are defined as indicated in Claim 1, to processes for their preparation and to their use for the control and prevention of disorders of the cardiovascular system, in particular for the control and prevention of angina pectoris, and for the treatment of erectile dysfunctions.
    Type: Grant
    Filed: May 25, 1993
    Date of Patent: November 1, 1994
    Assignee: Cassella Aktiengesellschaft
    Inventors: Joachim Brendel, Karl Schonafinger, Helmut Bohn
  • Polarized reversible magnet
    Patent number: 5196816
    Abstract: A polarized, reversible magnet with an essentially U-shaped yoke includes an upper coil former flange constructed like a frame and which fronts on yoke legs provided with tab-like integral moldings which in turn engage recesses of the upper coil former flange. Permanent magnets and pole pieces are inserted from above through appropriate openings of the upper coil former flange into the magnetic system.
    Type: Grant
    Filed: March 25, 1992
    Date of Patent: March 23, 1993
    Assignee: Harting Elektronik GmbH
    Inventors: Dietmar Harting, Ernst-Heinrich Hartung, Joachim Brendel, Wilhelm Niermann