Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a fail safe feature that activates during an interrupted dose delivery event. A dose selector having a projecting rib engages a protrusion on a snap element to prevent the dose knob from moving distally if a user removes an axial force in the proximal direction during dose delivery. The dose setting mechanism can further include a reuse prevention feature.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery.

Abstract: A collection of two or more dose delivery mechanisms and two or more medicament containers includes a first dose delivery mechanism comprising a first keyed connector and a second dose delivery mechanism comprising a second keyed connector. A first holder having a distal end with a third keyed connector. A second holder having a distal end with a fourth keyed connector. The first keyed connector not capable of forming a connection with the fourth keyed connector and the second keyed connector not capable of forming a connection with the third keyed connector. The first keyed connector configured to engage and form a connection with the third keyed connector and the second keyed connector configured to engage and form a connection with the fourth keyed connector.

Abstract: A dose setting mechanism is provided that includes a dose knob, a dose selector, a radial projecting rib and a snap element. The radial projecting rib is positioned circumferentially on an inside surface of the dose selector. The snap element includes a protrusion. The protruding rib has a reduced section that allows the protruding rib to move axially relative to the protrusion to initiate dose delivery.

Abstract: A dose delivery mechanism for a medicament delivery device includes a housing, a piston rod, and an adjusting element. The housing is configured to connect to a medicament container sealed by a plunger. In the assembled state, the dose delivery mechanism is configured to move the piston rod axially in a proximal direction with respect to the housing during dose delivery such that the piston rod exerts an axial force in the proximal direction on the plunger of the medicament container to expel a medicament from the medicament container.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery.

Abstract: A medicament delivery device for a mixing process to create a therapeutic substance for delivery within a multi-chambered cartridge, the delivery device includes a distal part with a dose setting mechanism having a housing, a dose setting knob, an injection button, a piston rod capable of moving axially along the longitudinal axis of the housing during dose delivery, and a return ring configured to reset the piston rod to a starting position. The delivery device also includes a proximal part including a cartridge holder configured to accept a multi-chambered cartridge, the cartridge holder including a screw driven sleeve configured for attachment to the distal part and rotation of the screw driven sleeve performing a medicament mixing process within the multi-chambered cartridge.

Abstract: A kit includes a drug delivery device and a dispensing unit. The drug delivery device includes a housing, a resetting element and a piston rod and the dispensing unit includes a cartridge holder. The cartridge holder is configured to be mounted to the housing and to receive a cartridge filled with a drug. The piston rod is configured to move in a proximal direction out of the housing to eject the drug and the resetting element is configured to rotate relative to the housing when no dispensing unit is attached to the housing and to thereby move the piston rod back into the housing. The dispensing unit is configured to press axially against the resetting element upon mounting to the housing to move the resetting element in the distal direction into the housing, and thereby rotationally lock the resetting element with respect to the housing.

Abstract: A set of at least two drug delivery devices includes a first drug delivery device and a second drug delivery device, The first and second drug delivery devices each include a first set of mutual members that are identical, and the first drug delivery device and the second drug delivery device each include a second set of distinguishing members that differ. The first drug delivery device includes a first connection device for attaching a first dispensing unit to the first drug delivery device and the second drug delivery device includes second connection device for attaching a second dispensing unit to the second drug delivery device, the first and second connection devices differ from each other so that the second dispensing unit is not attachable to the first connection device and the first dispensing unit is not attachable to the second connection device.

Abstract: An injection device includes a housing, a dosing member held so as to be rotatable and fixed in the housing and an injection sleeve held so as to be rotationally fixed in relation to the housing and displaceable therein. A latching unit of the injection device is configured to act between two components thereof which, during setting of an amount of injection fluid to be dispensed, move relative to one another. A set amount of injection fluid is unequivocally assigned to each relative position of the two components.

Abstract: An injection device includes a housing, a dosing member held so as to be rotatable and fixed in the housing and an injection sleeve held so as to be rotationally fixed in relation to the housing and displaceable therein. A latching unit of the injection device is configured to act between two components thereof which, during setting of an amount of injection fluid to be dispensed, move relative to one another. A set amount of injection fluid is unequivocally assigned to each relative position of the two components.

Abstract: A non-slip dose delivery mechanism includes a housing, a non-rotating piston rod, a nut, a piston rod guide, a driver, a ratchet and a brake. The non-rotating piston rod has a threaded outer surface. The nut includes an inner surface in threaded engagement with the threaded outer surface of the non-rotating piston rod. The nut is configured to rotate and translate axially in a proximal direction relative to the non-rotating piston rod during dose setting. The piston rod guide is rotationally fixed relative to the housing and is configured to prevent rotation of the piston rod. The driver includes an inner surface and an outer surface, the inner surface being in a rotationally fixed engagement with the nut. The ratchet is rotationally fixed to relative to the housing. The brake is positioned between the nut and the ratchet.

Abstract: An injection device incorporating a dose setting mechanism that contains a dose selector having a fail safe feature that activates during an interrupted dose delivery event where a projecting rib engages a protrusion on a snap element to prevent the dose knob from moving distally when a user removes an axial force in the proximal direction during dose delivery, intermediate stops to assist the user in dialing a dose and an injection feedback mechanism.

Abstract: An injection device is for automatically squeezing injection liquid from a container and includes: a housing; an injection spring configured to cause squeezing of the injection liquid from the container; the injection device defining a longitudinal central axis and a proximal direction; a metering piston mounted so as to be movable in the direction of the longitudinal central axis of the injection device; the metering piston being configured to, when squeezing injection liquid, move in the proximal direction; a setting device for setting the quantity of injection liquid to be squeezed; an end stop which establishes a terminal position of the metering piston; and, the setting device having an adjustment unit configured to adjust the position of the end stop.

Abstract: An injection device includes a housing; a receptacle for injection fluid; a dosing piston to press out the injection fluid; a feed part connected to the dosing piston via a first threaded connection; a slide having a thread of a second threaded connection; and, a setting part having a thread of a third threaded connection and configured to set an amount of injection fluid to be dispensed. The setting part moves in the distal direction by virtue of the third threaded connection when the amount of injection fluid to be dispensed is being set. The setting part can move in the proximal direction when the injection fluid is pressed out. A latching unit defines a latching position of the setting part and acts between the setting part and housing. Each latching position has an unequivocal rotational position of the setting part in relation to the housing assigned thereto.

Abstract: A medicament delivery device is presented for administering a therapeutic substance from a multi-chamber cartridge. The medicament delivery device performs a mixing process to create the therapeutic substance for delivery within the multi-chambered cartridge, where the delivery device includes a distal part comprising a dose setting mechanism having a housing, a dose setting knob, an injection button, a piston rod capable of moving axially along the longitudinal axis of the housing during dose delivery, and a return ring configured to reset the piston rod to a starting position. The delivery device also includes a proximal part comprising a cartridge holder configured to accept a multi-chambered cartridge, where the cartridge holder comprises a screw driven sleeve configured for attachment to the distal part and where rotation of the screw driven sleeve performs a medicament mixing process within the multi-chambered cartridge.

Abstract: A dose setting mechanism for a drug delivery device is presented that includes one or more potentiometers whereby relative motion and distances traveled between components in the dose setting mechanism are determined by monitoring and measuring changes in electrical resistance using a measuring device in electrical communication with the one or more potentiometers.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery.

Abstract: An injection device incorporating a dose setting mechanism is presented where the dose setting mechanism contains a dose selector having one or more dose stops corresponding to a finite set of predetermined fixed doses, where the set of finite predetermined fixed doses includes a lowest fixed dose and one or more higher fixed doses, and where at least one of the one or more higher fixed doses is equal to the lowest fixed dose plus a fractional amount of the lowest fixed dose. The dose setting mechanism can further include a floating spline that is rotationally engaged with a snap element such that the snap element can rotate relative to the floating spline during both dose setting and dose delivery.