Abstract: A continuous process for the preparation of inorganic and organic bead polymers using a static micromixer is disclosed. The bead polymers obtainable by the process according to the invention have a very uniform particle size distribution, which can be set in a range of between 0.1 and 300 &mgr;m.

Abstract: The present invention relates to a novel chromatographic process which is suitable for the purification of cyclosporin-containing crude extracts on industrial scale. In this process, the conventional preparative chromatographic separation methods are completely or at least partially replaced by the simulated moving bed method (SMB). The cyclosporin A obtained corresponds both to the quality requirements of USP XXIII and of EUROPEAN PHARMACOPOEIA, 2nd Edition 1995.

Abstract: Moldings, preferably comprising polyester which contains oxide particles which have been subjected to a surface modification with a silylating agent of the formula I?R.sup.1 R.sup.2 R.sup.3 !Si--(CH.sub.2).sub.l --X--R.sup.4 (I)whereinR.sup.1 is Cl or alkoxy having 1 to 6 carbon atoms,R.sup.2 and R.sup.3 are alkyl having 1 to 6 carbon atoms or R.sup.1,l is a number from 1 to 6,X is a single bond, O, NH, CONH or NHCONH,R.sup.4 is ##STR1## where Y is CH, ##STR2## Z is OR or two radicals Z together are --O-- or NR and m and n are a number from 0 to 6, or R.sub.4 is ##STR3## where X is a single bond and R, R' and R" are H or alkyl having 1 to 6 carbon atoms,and the use of said moldings are described.

Abstract: The invention relates to oxide particles which have a surface modification by covalently bonded organic groups which allow covalent bonding into polymer materials. These particles are particularly advantageous in their use as fillers or modifying agents in polymer materials, in particular polymer films.

Abstract: The invention is directed to separating materials comprising a primary or secondary aliphatic hydroxyl group-containing support coated with at least one covalently bonded polymer, wherein(1) the covalently bonded polymers are bonded to the support by graft polymerization via the .alpha.-carbon atoms of the hydroxyl groups, and(2) the polymer contains identical or different recurring units of the formula I ##STR1## wherein R.sup.1 is H or CH.sub.3 ;Y is ##STR2## R' and R" are each independently H or CH.sub.3, R.sup.2 and R.sup.3 are each independently(a) C.sub.1-10 -alkyl, phenyl, phenyl-C.sub.1-10 -alkyl, cycloalkyl, C.sub.1-10 -alkyl-cycloalkyl or C.sub.1-10 -alkylphenyl,(b) one of the above groups in (a) monosubstituted or polysubstituted by each of amino, mono- or dialkylamino, trialkylammonium, carboxyl, or sulfonyl,(c) a cyclic or bicyclic radical having 5-10 C atoms, wherein one or more CH or CH.sub.2 groups is replaced by (i) N or NH, (ii) N or NH and S, or (iii) N or NH and O, or(d) one of R.sup.

Abstract: The invention relates to separating materials for thin-layer chromatography, based on sorbent-coated supports, the sorbent essentially comprising optically active poly(meth)acrylamides bonded to silica gel, and a binder system comprising a mixture of carboxyl-containing polyvinyl and acrylate polymers.

Abstract: The invention relates to silane derivatives of the formula I ##STR1## their preparation by hydrosilylation of corresponding (meth)acrylamides and their use as silylating agents.

Abstract: Highly monodispersed nonporous spherical SiO.sub.2 particles are prepared having mean particle diameters between 0.05 and 10 .mu.m with a standard deviation of not more than 5% and a method for the preparation of such particles. The particles can be produced by a two step process wherein first a sol of primary particles is prepared by hydrolytic polycondensation of tetraalkoxysilanes in an aqueous/alcoholic ammoniacal medium. The SiO.sub.2 particles are then converted to the desired particle size by a continuous measured addition of tetraalkoxysilane or organotrialkoxysilane controlled by the extent of the reaction. The SiO.sub.2 particles produced by this process are particularly useful as sorption material in chromatography.

Abstract: Absorbents based on optically active poly(meth)acrylamides, e.g. bonded to silica gel, can be used for separating racemic mixtures into their optical antipodes.

Abstract: Highly monodispersed nonporous spherical SiO.sub.2 particles are prepared having mean particle diameters between 0.05 and 10 .mu.m with a standard deviation of not more than 5% and a method for the preparation of such particles. The particles can be produced by a two step process wherein first a sol of primary particles is prepared by hydrolytic polycondensation of tetraalkoxysilanes in an aqueous/alcoholic ammoniacal medium. The SiO.sub.2 particles are then converted to the desired particle size by a continuous measured addition of tetraalkoxysilane or organotrialkoxysilane controlled by the extent of the reaction. The SiO.sub.2 particles produced by this process are particularly useful as sorption material in chromatography.