Patents by Inventor Joachim Mittendorf

Joachim Mittendorf has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 5-fluoro-1H-pyrazolopyridines and their use
    Patent number: 8420656
    Abstract: The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
    Type: Grant
    Filed: May 19, 2011
    Date of Patent: April 16, 2013
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Jens Ackerstaff, Nils Griebenow, Walter Kroh, Andreas Knorr, Eva-Maria Becker, Frank Wunder, Volkhart Min-Jian Li, Elke Hartmann, Joachim Mittendorf, Karl-Heinz Schlemmer, Rolf Jautelat, Donald Bierer
  • Aliphatically substituted pyrazolopyridines, and the use thereof
    Patent number: 8334291
    Abstract: The present application relates to novel aliphatically substituted pyrazolopyridines, to processes for their preparation, to their use, alone or in combination, for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: December 8, 2009
    Date of Patent: December 18, 2012
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hartmut Schirok, Nils Griebenow, Chantal Fürstner, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder, Stefan Heitmeier
  • Hetaryloxy-substituted phenylamino pyrimidines as Rho kinase inhibitors
    Patent number: 8329716
    Abstract: The invention relates to hetaryloxy-substituted phenylaminopyrimidines, to a process for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular cardiovascular disorders.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: December 11, 2012
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hartmut Schirok, Martin Radtke, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Mark Jean Gnoth, Klaus Münter, Dieter Lang, Santiago Figueroa Perez, Michael Thutewohl, Samir Bennabi, Heimo Ehmke
  • Pyrazolopyridine, indazole, imidazopyridine, imidazopyrimidine, pyrazolopyrazine and pyrazolopyridine derivatives as stimulators of guanylate cyclase for cardiovascular disorders
    Patent number: 8309551
    Abstract: The present application relates to novel azabicyclic compounds, processes for their preparation, their use alone or in combinations for the treatment and/or prevention of diseases, and their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: September 1, 2007
    Date of Patent: November 13, 2012
    Assignee: Bayer Intellectual Property GmbH
    Inventors: Hartmut Schirok, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder, Friederike Stoll, Karl-Heinz Schlemmer
  • Aza-bicyclic compounds and their use as stimulators of soluble guanylate cyclase
    Patent number: 8114400
    Abstract: The present application relates to novel azabicyclic compounds, processes for their preparation, their use alone or in combinations for the treatment and/or prevention of diseases, and their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Grant
    Filed: November 14, 2007
    Date of Patent: February 14, 2012
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Hartmut Schirok, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder
  • BENZIMIDAZOLE AND PYRAZOLOPYRIDINE DERIVATIVES FOR TREATING AND/OR PREVENTING CARDIOVASCULAR DISEASES
    Publication number: 20120029002
    Abstract: The present application relates to novel fused, heteroatom-bridged pyrazole and imidazole derivatives, to processes for their preparation, to their use, alone or in combination, for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: January 5, 2010
    Publication date: February 2, 2012
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Alexander Straub, Frank Süßmeier, Frank Wunder, Johannes-Peter Stasch, Volkhart Min-Jian Li, Joachim Mittendorf
  • Substituted 5-fluoro-1H-pyrazolopyridines and their use
    Publication number: 20120022084
    Abstract: The present application relates to novel substituted 5-fluoro-1H-pyrazolopyridines, to processes for their preparation, to their use alone or in combinations for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of cardiovascular disorders.
    Type: Application
    Filed: May 19, 2011
    Publication date: January 26, 2012
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Markus Follmann, Johannes-Peter Stasch, Gorden Redlich, Jens Ackerstaff, Nils Griebenow, Walter Kroh, Andreas Knorr, Eva-Maria Becker, Frank Wunder, Volkhart Min-Jian Li, Elke Hartmann, Joachim Mittendorf, Karl-Heinz Schlemmer, Rolf Jautelat, Donald Bierer
  • NOVEL ALIPHATICALLY SUBSTITUTED PYRAZOLOPYRIDINES, AND THE USE THEREOF
    Publication number: 20110245273
    Abstract: The present application relates to novel aliphatically substituted pyrazolopyridines, to processes for their preparation, to their use, alone or in combination, for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: December 8, 2009
    Publication date: October 6, 2011
    Applicant: BAYER SCHERING PHARMA AKTIENGESELLSCHAFT
    Inventors: Hartmut Schirok, Nils Griebenow, Chantal Fürstner, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder, Stefan Heitmeier
  • NOVEL AZA-BICYCLIC COMPOUNDS AND THEIR USE AS STIMULATORS OF SOLUBLE GUANYLATE CYCLASE
    Publication number: 20110038857
    Abstract: The present application relates to novel azabicyclic compounds, processes for their preparation, their use alone or in combinations for the treatment and/or prevention of diseases, and their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: November 14, 2007
    Publication date: February 17, 2011
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Hartmut Schirok, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder
  • Heteroaryloxy-substituted phenylaminopyrimidines as rho-kinase inhibitors
    Patent number: 7737153
    Abstract: The invention relates to heteroaryloxy-substituted phenylaminopyrimidines, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular diseases. The inventive compounds inhibit Rho-Kinase.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: June 15, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Achim Feurer, Samir Bennabi, Heike Heckroth, Hartmut Schirok, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Jean Mark Gnoth, Klaus Münter, Dieter Lang, Santiago Figueroa Perez, Heimo Ehmke
  • Substituted phenylamino-pyrimidines
    Patent number: 7723347
    Abstract: The invention relates to substituted phenylaminopyrimidines, to a process for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular cardiovascular disorders.
    Type: Grant
    Filed: April 14, 2005
    Date of Patent: May 25, 2010
    Assignee: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Hartmut Schirok, Johannes-Peter Stasch, Raimund Kast, Klaus Münter, Marc Jean Gnoth, Santiago Figureoa Perez, Michael Thutewohl, Samir Bennabi, Dieter Lang, Joachim Mittendorf, Martin Radtke, Heimo Ehmke
  • 3-Tetrazolyl Indazoles, 3-Tetrazolyl Pyrazolopyridines, and use Thereof
    Publication number: 20100113507
    Abstract: The present application relates to novel 3-tetrazolylindazole and 3-tetrazolylpyrazolo[3,4-b]-pyridine derivatives, processes for their preparation, their use alone or in combination for the treatment and/or prophylaxis of diseases, and their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: April 30, 2007
    Publication date: May 6, 2010
    Applicant: BAYER HEALTHCARE AG
    Inventors: Chantal Fürstner, Hartmut Schirok, Nils Griebenow, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder
  • PYRAZOLOPYRIDINE, INDAZOLE, IMIDAZOPYRIDINE, IMIDAZOPYRIMIDINE, PYRAZOLOPYRAZINE AND PYRAZOLOPYRIDINE DERIVATIVES AS STIMULATORS OF GUANYLATE CYCLASE FOR CARDIOVASCULAR DISORDERS
    Publication number: 20100029653
    Abstract: The present application relates to novel azabicyclic compounds, processes for their preparation, their use alone or in combinations for the treatment and/or prevention of diseases, and their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: September 1, 2007
    Publication date: February 4, 2010
    Applicant: Bayer Schering Pharma Aktiengesellschaft
    Inventors: Hartmut Schirok, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder, Friederike Stoll, Karl-Heinz Schlemmer
  • Heterocyclic Substituted, Anellated Pyrazole Derivative and its uses
    Publication number: 20100004235
    Abstract: The present application relates to novel heterocyclyl-substituted fused pyrazole derivatives, to processes for their preparation, to their use, alone or in combination, for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.
    Type: Application
    Filed: April 17, 2007
    Publication date: January 7, 2010
    Applicant: BAYER HEALTHCARE AG
    Inventors: Hartmut Schirok, Nils Griebenow, Chantal Fürstner, Joachim Mittendorf, Johannes-Peter Stasch, Frank Wunder, Karl-Heinz Schlemmer, Stefan Heitmeier, Friederike Stoll
  • Substituted Phenylamino-Pyrimidines
    Publication number: 20080269268
    Abstract: The invention relates to substituted phenylaminopyrimidines, to a process for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular cardiovascular disorders.
    Type: Application
    Filed: April 14, 2005
    Publication date: October 30, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Hartmut Schirok, Johannes-Peter Stasch, Raimund Kast, Klaus Munter, Mark Jean Gnoth, Santiago Figureoa Perez, Michael Thutewohl, Samir Bennabi, Dieter Lang, Joachim Mittendorf, Martin Radtke, Heimo Ehmke
  • Pyrrolopyridine-Substituted Benzol Derivatives for Treating Cardiovascular Diseases
    Publication number: 20080249105
    Abstract: The invention relates to heteroaryl-substituted benzenes, to a process for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular cardiovascular disorders.
    Type: Application
    Filed: November 26, 2004
    Publication date: October 9, 2008
    Applicant: Bayer Healthcare AG
    Inventors: Samir Bennabi, Heike Heckroth, Hartmut Schirok, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Mark Jean Gnoth, Klaus Minter, Dieter Lang, Santiago Figueroa Perez, Marcus Bauser, Achim Feurer, Heimo Ehmke
  • Hetaryloxy-Substituted Phenylamino Pyrimidines as Rho Kinase Inhibitors
    Publication number: 20080139595
    Abstract: The invention relates to hetaryloxy-substituted phenylaminopyrimidines, to a process for their preparation and to their use for preparing medicaments for the treatment and/or prophylaxis of diseases in humans and animals, in particular cardiovascular disorders.
    Type: Application
    Filed: March 30, 2005
    Publication date: June 12, 2008
    Applicant: Bayer HealthCare AG
    Inventors: Hartmut Schirok, Martin Radtke, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Mark Jean Gnoth, Klaus Munter, Dieter Lang, Santiago Figueroa Perez, Michael Thutewohl, Samir Bennabi, Heimo Ehmke
  • Heteroaryloxy-substituted phenylaminopyrimidines as rho-kinase inhibitors
    Publication number: 20060241127
    Abstract: The invention relates to heteroaryloxy-substituted phenylaminopyrimidines, to methods for the production thereof, and to the use of the same for producing medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular diseases. The inventive compounds inhibit Rho-Kinase.
    Type: Application
    Filed: October 16, 2003
    Publication date: October 26, 2006
    Applicant: BAYER HEALTHCARE AG
    Inventors: Achim Feurer, Samir Bennabi, Heike Heckroth, Hartmut Schirok, Joachim Mittendorf, Raimund Kast, Johannes-Peter Stasch, Jean Gnoth, Klaus Munter, Dieter Lang, Santiago Perez, Heimo Ehmke
  • Arylsulphonamides and analogues
    Patent number: 6727279
    Abstract: The present invention relates to novel arylsulphonamides and analogues, to processes for their preparation and to their use for the prophylaxis and treatment of neurodegenerative disorders, in particular for the treatment of cerebral apoplexy, craniocerebral trauma, pain and spasticity.
    Type: Grant
    Filed: August 21, 2002
    Date of Patent: April 27, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Joachim Mittendorf, Jürgen Dressel, Michael Matzke, Jörg Keldenich, Frank Mauler, Jean-Marie-Victor de Vry, Jürgen Franz, Peter Spreyer, Verena Vöhringer, Joachim Schumacher, Michael-Harold Rock, Ervin Horvàth, Arno Friedl, Klaus-Helmut Mohrs, Siegfried Raddatz, Reinhard Jork
  • Substituted amidoalkyl-uracils and their use
    Patent number: 6649618
    Abstract: Novel amidoalkyl-uracil derivatives of the formula (I) in which A represents 1-3 ring atoms and X represents optionally substituted (C2-C10)alkylene or (C3-C8)cycloalkylene as defined in claim 1, a process for their preparation, and their use as medicaments for the prophylaxis and/or treatment of disorders are described.
    Type: Grant
    Filed: July 16, 2001
    Date of Patent: November 18, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Michael Härter, Barbara Albrecht, Michael Gerisch, Gabriele Handke, Joachim Hütter, Axel Jensen, Thomas Krahn, Joachim Mittendorf, Felix Oehme, Karl-Heinz Schlemmer, Henning Steinhagen