Patents by Inventor Joachim Nozulak

Joachim Nozulak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic S1P Receptor Modulators
    Publication number: 20100179153
    Abstract: The invention relates to novel heterocyclic compounds of the formula in which all of the variables are as defined in the specification, in free form or in salt form, to their preparation, b their use as medicaments and to medicaments comprising them.
    Type: Application
    Filed: April 21, 2008
    Publication date: July 15, 2010
    Inventors: Henri Mattes, Joachim Nozulak, David Orain, Kumlesh K. Dev
  • 1H-QUINAZ0LINE-2,4-DIONES
    Publication number: 20100144747
    Abstract: The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) are and combinations comprising compounds of formula (I) are disclosed.
    Type: Application
    Filed: September 29, 2009
    Publication date: June 10, 2010
    Inventors: Hans ALLGEIER, Yves AUBERSON, David CARCACHE, Philipp FLOERSHEIM, Christel GUIBOURDENCHE, Wolfgang FROESTL, Jörg KALLEN, Manuel KOLLER, Henri MATTES, Joachim NOZULAK, David ORAIN, Johanne RENAUD
  • COMBINATIONS OF NICOTINIC ACETYLCHOLINE ALPHA 7 RECEPTOR AGONISTS
    Publication number: 20100125063
    Abstract: Combinations which comprise at least one nicotinic acetylcholine alpha 7 receptor agonist and at least one compound selected from the group consisting of (a) conventional antipsychotics (b) atypical antipsychotics (c) cognition, attention and/or memory enhancers (d) and to use of these combinations in the treatment of psychiatric disorders.
    Type: Application
    Filed: January 20, 2010
    Publication date: May 20, 2010
    Inventors: Hans O. KALKMAN, Joachim NOZULAK, Annick VASSOUT, Konstanze HURTH, Dominik FEUERBACH, Conrad GENTSCH, Graeme BILBE
  • ACETYLENE DERIVATIVES
    Publication number: 20100099682
    Abstract: The invention provides compounds of formula (I) wherein R1 represents hydrogen or alkyl; R2 represents an unsubstituted or substituted heterocycle or R2 represents an unsubstituted or substituted aryl; R3 represents alkyl or halogen; X represents a single bond or an alkandiyl-group, optionally interrupted by one or more oxygen atoms or carbonyl groups or carbonyloxy groups in free base or acid addition salt form, processes for their preparation and their use as pharmaceuticals.
    Type: Application
    Filed: September 17, 2009
    Publication date: April 22, 2010
    Inventors: Ralf GLATTHAR, Thomas J. Troxler, Thomas Zoller, Joachim Nozulak
  • Acetylene derivatives
    Patent number: 7696379
    Abstract: The invention provides compounds of formula (I) wherein R1 represents hydrogen or alkyl; R2 represents an unsubstituted or substituted heterocycle or R2 represents an unsubstituted or substituted aryl; R3 represents alkyl or halogen; X represents a single bond or an alkandiyl-group, optionally interrupted by one or more oxygen atoms or carbonyl groups or carbonyloxy groups in free base or acid addition salt form, processes for their preparation and their use as pharmaceuticals.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: April 13, 2010
    Assignee: Novartis AG
    Inventors: Ralf Glatthar, Thomas J. Troxler, Thomas Zoller, Joachim Nozulak
  • Substituted 1H-quinazoline-2,4-diones useful as AMPA receptor ligands
    Patent number: 7655666
    Abstract: The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) are and combinations comprising compounds of formula (I) are disclosed.
    Type: Grant
    Filed: April 10, 2006
    Date of Patent: February 2, 2010
    Assignee: Novartis AG
    Inventors: Hans Allgeier, Yves Auberson, David Carcache, Philipp Floersheim, Christel Guibourdenche, Wolfgang Froestl, Jörg Kallen, Manuel Koller, Henri Mattes, Joachim Nozulak, David Orain, Johanne Renaud
  • ORGANIC COMPOUNDS
    Publication number: 20090099243
    Abstract: The invention relates to compound of the formula (I) in which the substituents are as defined in the specification; in free base form or in acid addition salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: October 15, 2008
    Publication date: April 16, 2009
    Inventors: Joachim Nozulak, David Orain
  • ORGANIC COMPOUNDS
    Publication number: 20090099244
    Abstract: The invention relates to compound of the formula I wherein the substituents are as defined in the specification; in free base form or in acid addition salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: October 15, 2008
    Publication date: April 16, 2009
    Inventors: Joachim Nozulak, David Orain
  • ORGANIC COMPOUNDS
    Publication number: 20090099199
    Abstract: The invention relates to compound of the formula I wherein the substituents are as defined in the specification; in free base form or in acid addition salt form; to its preparation, to its use as medicament and to medicaments comprising it.
    Type: Application
    Filed: October 15, 2008
    Publication date: April 16, 2009
    Inventors: Joachim Nozulak, David Orain, Simona Cotesta
  • Combinations of Nicotinic Acetylcholine Alpha 7 Receptor Antagonists
    Publication number: 20080306081
    Abstract: Combinations which comprise at least one nicotinic acetylcholine alpha 7 receptor agonist and at least one compound selected from the group consisting of (a) conventional antipsychotics (b) atypical antipsychotics (c) cognition, attention and/or memory enhancers (d) and to use of these combinations in the treatment of psychiatric disorders.
    Type: Application
    Filed: November 3, 2005
    Publication date: December 11, 2008
    Applicant: NOVARTIS AG
    Inventors: Hans O. Kalkman, Joachim Nozulak, Annick Vassout, Konstanze Hurth, Dominik Feuerbach, Conrad Gentsch, Graeme Bilbe
  • Pyrrolidine and Piperidine Acetylene Derivatives for Use as Mglur5 Antagonists
    Publication number: 20080269250
    Abstract: The invention provides compounds of formula (I) wherein the substituents are as defined in the description, processes and intermediates for their preparation and their use as pharmaceuticals.
    Type: Application
    Filed: February 20, 2006
    Publication date: October 30, 2008
    Inventors: Ralf Glatthar, Thomas J. Troxler, Thomas Zoller, Joachim Nozulak
  • Organic Compounds
    Publication number: 20080242698
    Abstract: The invention relates to novel diamines of the formula in which all variables are as defined in the specification, in free base form or in acid addition salt form, to their preparation, to their use as medicaments and to medicaments comprising them.
    Type: Application
    Filed: August 29, 2006
    Publication date: October 2, 2008
    Inventors: Peter Josef Flor, Andreas Marzinzik, Joachim Nozulak, Silvio Ofner, Bernard Lucien Roy, Carsten Spanka
  • Acetylene Derivatives
    Publication number: 20080214673
    Abstract: The invention provides compounds of formula (I) wherein R1 represents hydrogen or alkyl; R2 represents an unsubstituted or substituted heterocycle or R2 represents an unsubstituted or substituted aryl; R3 represents alkyl or halogen; X represents a single bond or an alkandiyl-group, optionally interrupted by one or more oxygen atoms or carbonyl groups or carbonyloxy groups in free base or acid addition salt form, processes for their preparation and their use as pharmaceuticals.
    Type: Application
    Filed: April 24, 2006
    Publication date: September 4, 2008
    Inventors: Ralf Glatthar, Thomas J. Troxler, Thomas Zoller, Joachim Nozulak
  • 1H-Quinazoline-2,4-Diones
    Publication number: 20080153836
    Abstract: The present invention relates to 1H-Quinazoline-2,4-diones of formula (I) wherein R1 and R2 are as defined in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them. Further, intermediates for the manufacture of compounds of formula (I) are and combinations comprising compounds of formula (I) are disclosed.
    Type: Application
    Filed: April 10, 2006
    Publication date: June 26, 2008
    Inventors: Hans Allgeier, Yves Auberson, David Carcache, Philipp Floersheim, Christel Guibourdenche, Wolfgang Froestl, Jorg Kallen, Manuel Koller, Henri Mattes, Joachim Nozulak, David Orain, Johanne Renaud
  • Quinazoline Derivatives
    Publication number: 20070208018
    Abstract: The present invention relates to 1H-Quinazoline-2,4-dione derivatives of formula(I) wherein the substituents are defined as in the specification, their preparation, their use as pharmaceuticals, and pharmaceutical compositions containing them.
    Type: Application
    Filed: July 26, 2005
    Publication date: September 6, 2007
    Applicant: NOVARTIS AG
    Inventors: Hans Allgeier, Wolfgang Froestl, Manuel Koller, Henri Mattes, Joachim Nozulak, Silvio Ofner, David Orain, Vittorio Rasetti, Johanne Renaud, Nicolas Soldermann, Philipp Floersheim
  • Benzisoxazoles
    Publication number: 20070197595
    Abstract: The present invention relates to novel fatty acid esters of the reversible Iloperidone metabolite P-88-8991, their preparation, their use as pharmaceuticals and pharmaceutical compositions containing them.
    Type: Application
    Filed: September 30, 2004
    Publication date: August 23, 2007
    Inventors: Joachim Nozulak, Hans Kalkman
  • Substituted pyrrolidine-2-ones
    Publication number: 20070172421
    Abstract: The invention relates to compounds of formula (I) Wherein R1, R2, R3, R4 and n are as defined in the specification, to processes for their manufacture, to their use as pharmaceuticals, in diagnosis, as PET ligands and to pharmaceutical or diagnostic compositions comprising such compounds.
    Type: Application
    Filed: May 27, 2005
    Publication date: July 26, 2007
    Inventors: Werner Muller, Joachim Nozulak, Bernard Roy, Dominik Feuerbach
  • 1,3 disubstituted pyrrolidines as ?-2-adrenoceptor antagonists
    Patent number: 7012085
    Abstract: The invention provides compounds of formula (I) wherein R0, R1, R2 and A are as defined in the description, and the preparation thereof. The compounds of formula (I) have high affinity as ?2 adrenoceptors and hence are useful as pharmaceuticals.
    Type: Grant
    Filed: January 26, 2001
    Date of Patent: March 14, 2006
    Assignee: Novartis AG
    Inventors: Max Peter Seiler, Joachim Nozulak
  • Azabicyclic carbamates and their use as &agr;-7 nicotinic acetylcholine receptor agonists
    Patent number: 6780861
    Abstract: The invention provides compounds of formula (I) wherein n, A, R1, R2 and R3 are as defined in the description, and the preparation thereof. The compounds of formula (I) are useful as pharmaceuticals.
    Type: Grant
    Filed: October 31, 2002
    Date of Patent: August 24, 2004
    Assignee: Novartis AG
    Inventor: Joachim Nozulak
  • Azabicyclic carbamates and their use as alpha-7 nicotinic acetylcholine receptor agonists
    Publication number: 20030166654
    Abstract: The invention provides compounds of formula (I) wherein n, A, R1, R2 and R3 are as defined in the description, and the preparation thereof. The compounds of formula (I) are useful as pharmaceuticals.
    Type: Application
    Filed: October 31, 2002
    Publication date: September 4, 2003
    Inventor: Joachim Nozulak