Abstract: The present invention concerns a bioactive implant material having a cartilage-inducing and/or bone-inducing activity composed of two components A and B, of which A is a bone-inducing and/or cartilage-inducing protein or protein mixture and preferably one or several proteins from the TGF-? superfamily, preferably MP52 or a DNA sequence coding therefor and B is a carrier matrix composed of calcium phosphate ceramics with an interconnecting microporosity which already alone has bone-inducing properties. The invention additionally concerns the production of these compounds and their use for the treatment of diseases which affect cartilage and/or bones as well as to treat damage to cartilage and/or bone tissue.

Abstract: The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous ?-tricalcium phosphate (?-TCP).

Abstract: The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous ?-tricalcium phosphate (?-TCP).

Abstract: The present invention concerns a bioactive implant material having a cartilage-inducing and/or bone-inducing activity composed of two components A and B, of which A is a bone-inducing and/or cartilage-inducing protein or protein mixture and preferably one or several proteins from the TGF-? superfamily, preferably MP52 or a DNA sequence coding therefor and B is a carrier matrix composed of calcium phosphate ceramics with an interconnecting microporosity which already alone has bone-inducing properties. The invention additionally concerns the production of these compounds and their use for the treatment of diseases which affect cartilage and/or bones as well as to treat damage to cartilage and/or bone tissue.

Abstract: An inhaler comprises a drivable milling disk (14) against which a solid active substance tablet (18) is brought into contact. The milling disk (14) can be driven via a spring drive or an electromotor in order to remove active substance particles from the active substance tablet (18). During usage of the inhaler, air is drawn in during inspiration via air conduits (24,26,28) and a mouthpiece (12) and entrains the removed active substance particles. In order to release the rotary drive of the milling disk (14), an air flap (60) is placed in the flow path of the drawn-in air. The air flap (60) is pivoted during inspiration by the drawn-in airflow and releases the rotary drive.

Abstract: The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous ?-tricalcium phosphate (?-TCP).

Abstract: The invention relates to a resorbable bone replacement and bone formation material (augmentation material) based on porous &bgr;-tricalcium phosphate (&bgr;-TCP).

Abstract: A solidified drug supply for generating inhalable drug particles with the aid of a metering device includes a removal unit, with the drug supply being brittle and textureless. The density and the mechanical strength of the drug supply is abraded everywhere in such a way that the structure of the material removed from one side of the drug supply by the metering device is uniform across the entire usage region in the direction of the removal.

Abstract: A device for mechanically generating inhalable active substance particles from a consolidated medication supply and for conveying the active substance particles into the respiratory tract, wherein, in order to generate the active substance particles, there is a drivable face mill against which the front of a medication supply in the form of a ring-shaped body can be pressed, whereby the ring-shaped body forms the beginning of an inhalation tube ending in a mouthpiece and in that the housing surrounding the ring-shaped body and the face mill is provided with air inlet openings in the blade area of the face mill and said air inlet openings, together with the depressions located between the blades and the inhalation tube, form an air channel leading to the mouthpiece.