Abstract: The invention relates to antibacterial amide macrocycles, to methods for the production thereof, and to the use of the same for producing pharmaceuticals for the treatment and/or prophylaxis of illness, especially bacterial infections.

Abstract: The present invention relates to new bromo- and chlorothiazolium salts of the formula (I) in which R1, R2, R3, R4, n and X? have the meaning indicated in the disclosure, a process for their preparation, their use as condensation reagents, particularly as peptide coupling reagents, and intermediates for the preparation of these compounds.

Abstract: This invention is directed to indole acetic acid derivatives and their use in pharmaceutical compositions for the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic disease. The invention is also directed to intermediates useful in preparation of indole acetic derivatives and to methods of preparation.

Abstract: The invention relates to antibacterial ester macrocycles of formula (I), methods for the production thereof, and the use thereof for producing medicaments used for the treatment and/or prophylaxis of diseases, particularly bacterial infections.

Abstract: The present invention relates to new bromo- and chlorothiazolium salts of the formula (I) in which R1, R2, R3, R4, n and X? have the meaning indicated in the disclosure, a process for their preparation, their use as condensation reagents, particularly as peptide coupling reagents, and intermediates for the preparation of these compounds.

Abstract: This invention relates to novel indane acetic acid derivatives which are useful in the treatment of diseases such as diabetes, obesity, hyperlipidemia, and atherosclerotic diseases. The invention also relates to intermediates useful in preparation of indane acetic derivatives and to methods of preparation.

Abstract: The invention relates to a process for the preparation of carboxamides, in particular peptides, from an acid component in the form of a compound containing at least one carboxyl group and an amine component in the form of a compound containing at least one primary or secondary amino group, and its use.

Abstract: The present invention relates to new bromo- and chlorothiazolium salts of the formula (I) in which R1, R2, R3, R4, n and X have the meaning indicated in the disclosure, a process for their preparation, their use as condensation reagents, particularly as peptide coupling reagents, and intermediates for the preparation of these compounds.

Abstract: The invention relates to antibacterial amide macrocycles and process for their preparation, their use for the treatment and/or prophylaxis of diseases, and to their use for producing medicaments for the treatment and/or prophylaxis of diseases, especially of bacterial infections.

Abstract: The present invention relates to heteroarylaminopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.

Abstract: The invention relates to a method for producing chiral amino acid derivatives, characterised in that free carboxylic acid groups in an amino acid derivative are first converted into nitro ketones, and said nitro ketones are then converted into the corresponding nitro alcohols and amino alcohols by means of reduction. The invention also relates to the nitro ketones and nitro alcohols obtained as intermediate products.

Abstract: The present invention relates to anilinopyrazole compounds, pharmaceutical compositions, and methods for treating diabetes and related disorders.

Abstract: The present invention relates to N-alkylated thiazolium salts, to a process for their preparation and also to their use as condensation and dehydrating agents.

Abstract: The invention relates to a process for the preparation of carboxamides, in particular peptides, from an acid component in the form of a compound containing at least one carboxyl group and an amine component in the form of a compound containing at least one primary or secondary amino group, and its use.

Abstract: The present invention relates to new bromo- and chlorothiazolium salts of the formula (I) 1

Abstract: Rhenium-catalyzed epoxidation of olefinic substrates is accelerated by the use of acclerants having a nitrogenous aromatic heterocyclic structure. Use of the accelerants also enables the use of aqueous hydrogen peroxide as an oxidant. To achieve optimum acceleration, the accelerant should have a concentration within a range from 2.0 mole percent to 100 mole percent of the acclerant with respect to 1 mole of the olefinic substrate. Use of the accelerant also results in an increased yield with respect to the conversion of the olefinic substrate to epoxide product.

Abstract: A rotor (2) surrounded by a strainer basket (3) is arranged vertically in a housing (1). Conveyor blades (7) arranged one above the other are distributed over the rotor (2) to convey plastic granules from a product inlet (14) arranged at the bottom of the housing to a discharge unit (15). A fan (19) is disposed in a discharge hood (16) and it has ejector blades (21) for assisting the radial discharge of the granules into unit (15). In order to change the residence time of the plastic granules in the dryer, a change in pressure is produced in the centrifugal dryer by replacing the fan with one having ejector blades whose outer diameter and/or length is different, the diameter of rotor (2) and its conveyor blades (7) being kept the same.

Abstract: A method for the separation of granulate and water in an after-treatment section following a granulator in which a vibrating screen receives the water and granulate mixture. In order to obtain low residual moisture without subsequent drying, the granulate-water mixture on the screen is subjected briefly to a vacuum over the entire width of the vibrating screen at longitudinally spaced locations, in alternation, from above and below the screen within the first third of the length of the screen.

Abstract: A cooling device for plastic granulate which is formed by cutting plastic strands emerging from a nozzle plate of an extruder and is fed to a stream of cooling water which adjoins the nozzle plate in the region of a cutting device. A pipe conducts the stream of cooling water containing the granulate to a granulate-water separator. In order to obtain a well-defined, infinitely adjustable dwell time of the granulate in the stream of cooling water, the pipe is essentially developed as a vertically arranged riser having a larger cross section passage area than that of the pipe itself. The upper outlet end of the riser is connected to the suction side of a feed pump, which serves as a section pump, and to a suction pipe which has an end connected to ambient atmosphere. A regulating valve is connected in the suction pipe. The delivery side of the feed pump communicates with the granulate-water separator.

Abstract: A method and apparatus for regulating the drive of dosaging devices for the controlled feeding of plastic particles, color concentrates and additives into a supply hopper of a screw extruder for producing a mixed plastic product of determined coloration, comprising periodically measuring the coloration of the mixed product at an outlet of the extruder by a spectrometer connected to a measurement probe, comparing the measured coloration of the mixed product with the coloration of the desired product, and adjusting the supply of the plastic product, concentrates and additives, as necessary, so that the measured coloration of the product at the outlet of the extruder is the same as the coloration of the desired product.