Patents by Inventor Joachim Wink

Joachim Wink has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vancoresmycin, a process for its production and its use as a pharmaceutical
    Publication number: 20020183267
    Abstract: The present invention relates to a compound named Vancoresmycin which is obtainable by cultivation of the microorganism HIL-006734 (DSM 12216), and to its pharmaceutically acceptable salts. The present invention further relates to a process for the production of Vancoresmycin, to the microorganism HIL-006734 (DSM 12216), to the use of Vancoresmycin and its pharmaceutically acceptable salts as pharmaceuticals, and in particular to their use as antibiotics, and to pharmaceutical compositions comprising Vancoresmycin or a pharmaceutically acceptable salt thereof.
    Type: Application
    Filed: March 25, 2002
    Publication date: December 5, 2002
    Inventors: Nirogi Venkata Satya Ramakrishna, Ravi Gaianan Bhat, Eyyammadichiyil Sankaranarayanan Sreekumar, Erra Koteswara Satya Vijayakumar, Shantilal Dayaram Naker, Uttara Vinayak Oak, Rajendra Prakash Tanpure, Cordula Hopmann, Michael Kurz, Joachim Wink, Gerhard Seibert, Dominique Le Beller, Jozsef Aszodi
  • Ustilipides, method for the production and the use thereof
    Patent number: 6472158
    Abstract: New active agents (ustilipides) formed by the microorganism Ustilago maydis, FH 2634, DSM 11494 during fermentation. The invention also relates to a method for the production of said ustilipides and to their use as medicaments in the treatment of schizophrenia or diseases caused by dopamine metabolic dysfunction. The invention further relates to medicaments containing ustilipides and to the microorganism Ustilago maydis, FH 2634, DSM 11494.
    Type: Grant
    Filed: July 21, 2000
    Date of Patent: October 29, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Laszló Vértesy, Michael Kurz, Gerhard Noelken, Joachim Wink
  • Citrullimycines, a process for their production and their use as pharmaceuticals
    Publication number: 20020065316
    Abstract: The present invention relates to novel active compounds named Citrullimycines, which are obtainable by cultivation of Streptomyces sp. ST 101396 (DSM 13309), and to their pharmaceutically acceptable salts and derivatives. The present invention further relates to a process for the production of the Citrullimycines, to the microorganism Streptomycetes sp. ST 101396 (DSM 13309), to the use of the Citrullimycines and their pharmaceutically acceptable salts and derivatives as pharmaceuticals, for example as inhibitors of the neurotensin receptor, and to pharmaceutical compositions comprising Citrullimycines or a pharmaceutically acceptable salt or derivative thereof.
    Type: Application
    Filed: October 1, 2001
    Publication date: May 30, 2002
    Inventors: Cordula Hopmann, Michael Kurz, Mark Bronstrup, Joachim Wink
  • Cyclipostins, process for their preparation and use thereof
    Publication number: 20020058645
    Abstract: The invention relates to compounds of formula I 1
    Type: Application
    Filed: June 22, 2001
    Publication date: May 16, 2002
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Michael Kurz, Joachim Wink
  • Vancoresmycin, a process for its production and its use as a pharmaceutical
    Patent number: 6387943
    Abstract: The present invention relates to a compound named Vancoresmycin which is obtainable by cultivation of the microorganism HIL-006734 (DSM 12216), and to its pharmaceutically acceptable salts. The present invention further relates to a process for the production of Vancoresmycin, to the microorganism HIL-006734 (DSM 12216), to the use of Vancoresmycin and its pharmaceutically acceptable salts as pharmaceuticals, and in particular to their use as antibiotics, and to pharmaceutical compositions comprising Vancoresmycin or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: November 9, 1999
    Date of Patent: May 14, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Nirogi Venkata Satya Ramakrishna, Ravi Gajanan Bhat, Eyyammadichiyil Sankaranarayanan Sreekumar, Erra Koteswara Satya Vijayakumar, Shantilal Dayaram Naker, Uttara Vinayak Oak, Rajendra Prakash Tanpure, Cordula Hopmann, Michael Kurz, Joachim Wink, Gerhard Seibert, Dominique Le Beller, Jozsef Aszodi
  • Pluraflavins and derivatives thereof, process for their preparation and use thereof
    Publication number: 20020028921
    Abstract: The invention relates to a compound of formula (l) 1
    Type: Application
    Filed: February 16, 2001
    Publication date: March 7, 2002
    Inventors: Laszlo Vertesy, Klaus Ehrlich, Martin Knauf, Joachim Wink, Francis P. Barbone, Elaine A. Powers, Elizabeth A. Cashman
  • Stromelysin inhibitors
    Patent number: 6337411
    Abstract: Compounds of the formula I are suitable for the production of pharmaceuticals for the prophylaxis and therapy of conditions whose course involves an increased activity of matrix-degrading enzymes, in particular stromelysin.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: January 8, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Cordula Hopmann, Martin Albert Knauf, Klaus-Ulrich Weithmann, Joachim Wink
  • Novel stromelysin inhibitors
    Publication number: 20010025029
    Abstract: Compounds of the formula I 1
    Type: Application
    Filed: December 15, 2000
    Publication date: September 27, 2001
    Inventors: Cordula Hopmann, Martin Albert Knauf, Klaus-Ulrich Weithmann, Joachim Wink
  • Antifungal peptides from scleroderma texense
    Patent number: 6221844
    Abstract: The invention relates to novel peptides, namely texenomycins, from Scleroderma texense, a process for their preparation and their use as pharmaceuticals, in particular as antimycotics. The texenomycins according to the present invention are distinguished in particular by the amino acid sequence I in which FS is an oxo fatty acid radical, Aib is aminoisobutyric acid and Arg-ol=argininol.
    Type: Grant
    Filed: May 18, 1999
    Date of Patent: April 24, 2001
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Heike Stump, Wilhelm Stahl, Joachim Wink, Astrid Markus, Herbert Kogler, Jürgen Backhaus
  • Lipopeptides from actinoplanes sp. with pharmacological action, process for their production and the use thereof
    Patent number: 6194383
    Abstract: The invention relates to lipopeptides with very homologous amino-acid sequences but different fatty acid residues (lipid portion) which are synthesized by Actinoplanes sp. during fermentation and are released into the culture medium, to a process for isolating the lipopeptides from the culture medium and purifying them, to the use of the lipopeptides as pharmacologically active substances, in particular against Gram-positive bacteria, and to Actinoplanes sp. DSM 7358 for producing the abovementioned lipopeptides.
    Type: Grant
    Filed: March 5, 1997
    Date of Patent: February 27, 2001
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Peter Hammann, Johannes Meiwes, Gerhard Seibert, László Vertesy, Joachim Wink, Astrid Markus
  • Lantibiotic related to actagardine, and processes for the preparation and use thereof
    Patent number: 6022851
    Abstract: The present invention relates to a novel lantibiotic having the formula NH.sub.2 --R-actagardine, where NH.sub.2 --R is the radical of the amino acid alanine, which is formed by the microorganism Actinoplanes liguriae, DSM 11797 or Actinoplanes garbadiensis, DSM 11796 during fermentation, chemical derivatives of the lantibiotic, a process for its preparation and the use of the lantibiotics as pharmaceuticals.
    Type: Grant
    Filed: October 14, 1998
    Date of Patent: February 8, 2000
    Assignee: Hoechst Marion Roussel Deutschland, GmbH
    Inventors: Laszlo Vertesy, Herbert Kogler, Matthias Schiell, Joachim Wink
  • Methods of treatment with novel antibiotic feglymycin
    Patent number: 5994307
    Abstract: This invention relates to the antibiotic feglymycin, as well as processes for its preparation and use. Feglymycin is represented by the structural formula (SEQ. ID. NO.
    Type: Grant
    Filed: December 2, 1998
    Date of Patent: November 30, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Laszlo Vertesy, Martin Knauf, Joachim Wink, Dieter Isert, Wilhelm Stahl, Gunther Riess, Jozsef Aszodi, Dominique Le Beller
  • Polyene antibiotics, 3874 H1 to H6, processes for their preparation and use
    Patent number: 5939399
    Abstract: Novel polyene antibiotics, 3874 H1 to H6, processes for their preparation and use which are suitable for treating fungal diseases, trichomonad diseases, and for treating diseases associated with an increased steroid concentration.
    Type: Grant
    Filed: August 19, 1997
    Date of Patent: August 17, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Laszlo Vertesy, Michael Kurz, Joachim Wink, Astrid Markus, Wilhelm Stahl
  • Antibiotic, feglymycin, processes for its preparation and its use
    Patent number: 5891851
    Abstract: This invention relates to the antibiotic feglymycin, as well as processes for its preparation and use.
    Type: Grant
    Filed: December 11, 1997
    Date of Patent: April 6, 1999
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Laszlo Vertesy, Martin Knauf, Joachim Wink, Dieter Isert, Wilhelm Stahl, Gunther Riess, Jozsef Aszodi, Dominique Le Beller
  • Antifungal polypeptide and process for its production
    Patent number: 5824874
    Abstract: The polypeptide with the sequence (SEQ ID NO:1)Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp-Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln -Ser-Gly-Lys-Thr-Ala-Ile-Cys-Lys-Cys-Tyr-Val-Lys-Lys-Cys-Pro-Arg-Asp-Gly-Al a-Lys-Cys-Glu-Phe-Asp-Ser-Tyr-Lys-Gly-Lys-Cys-Tyr-Cyscan be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent.Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.
    Type: Grant
    Filed: July 29, 1996
    Date of Patent: October 20, 1998
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Norbert Ulbrich, Rolf Hilgenfeld, Heinz Hanel, Burkhard Sachse, Peter Braun, Joachim Wink, Peter Eckes, Jurgen Logemann, Jozef Schell
  • Antifungal polypeptide and process for its production
    Patent number: 5589624
    Abstract: The polypeptide with the sequence (SEQ ID NO: 1)______________________________________ Ala--Thr--Tyr--Asn--Gly--Lys--Cys--Tyr--Lys--Lys--Asp-- Asn--Ile--Cys--Lys--Tyr--Lys--Ala--Gln--Ser--Gly--Lys-- Thr--Ala--Ile--Cys--Lys--Cys--Tyr--Val--Lys--Lys--Cys-- Pro--Arg--Asp--Gly--Ala--Lys--Cys--Glu--Phe--Asp--Ser-- Tyr--Lys--Gly--Lys--Cys--Tyr--Cys ______________________________________can be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent.Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.
    Type: Grant
    Filed: January 13, 1995
    Date of Patent: December 31, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Norbert Ulbrich, Rolf Hilgenfeld, Heinz Hanel, Burkhard Sachse, Peter Braun, Joachim Wink, Peter Eckes, Jurgen Logemann, Jozef Schell
  • Penicillium cultures capable of producing 10-membered ring lactones
    Patent number: 5561060
    Abstract: Penicillium cultures capable of producing 10-member ring lactones.It is possible with the aid of Penicillium strains to prepare new 10-membered ring lactones having a pharmacological action.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: October 1, 1996
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Joachim Wink, Susanne Grabley, Gerhard Seibert, Klaus Hutter, Axel Zeeck
  • Antifungal polypeptide and process for its production
    Patent number: 5421839
    Abstract: Antifungal polypeptide and process for its productionThe polypeptide with the sequence (SEQ ID NO: 1)Ala-Thr-Tyr-Asn-Gly-Lys-Cys-Tyr-Lys-Lys-Asp-Asn-Ile-Cys-Lys-Tyr-Lys-Ala-Gln -Ser-Gly-Lys-Thr-Ala-Ile-Cys- Lys-Cys-Tyr-Val-Lys-Lys-Cys-Pro-Arg-Asp-Gly-Ala-Lys-Cys-Glu-Phe-Asp-Ser-Ty r-Lys-Gly-Lys-Cys-Tyr-Cyscan be produced by the fermentation of Aspergillus giganteus and used as an antifungal agent.Expression of this polypeptide gene in plants strongly inhibits the growth of phytopathogenic fungi on the plant.
    Type: Grant
    Filed: October 30, 1992
    Date of Patent: June 6, 1995
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Norbert Ulbrich, Rolf Hilgenfeld, Heinz Hanel, Burkhard Sachse, Peter Braun, Joachim Wink, Peter Eckes, Jurgen Logemann, Jozef Schell
  • Process for the production of furans and lactones from streptomyces
    Patent number: 5252472
    Abstract: It is possible with the aid of various Streptomycetes species to prepare new compounds having a furan or lactone structure. These compounds have a pharmacological, especially antibiotic, action.
    Type: Grant
    Filed: February 7, 1992
    Date of Patent: October 12, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Susanne Grabley, Joachim Wink, Klaus Kuhlein, Gerhard Seibert, Klaus Hutter, Hermann Uhr, Axel Zeeck
  • Use of 10-membered ring lactones as lipid regulators
    Patent number: 5200424
    Abstract: The compound of the formula ##STR1## in which, independently of one another, R.sup.1 and R.sup.4 are hydrogen or hydroxyl,R.sup.2 and R.sup.3 are hydroxyl,R.sup.5 is hydrogen, hydroxyl or an oxo group, andR.sup.2 and R.sup.3, and R.sup.3 and R.sup.4, can each together form a double bond,has hypolipemic properties and is used for the preparation of a pharmaceutical for lowering serum cholesterol.
    Type: Grant
    Filed: August 26, 1991
    Date of Patent: April 6, 1993
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Ernold Granzer, Peter Hammann, Joachim Wink, Susanne Grabley