Patents by Inventor Joan A. Windsor

Joan A. Windsor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity human antibodies to human IL-4 receptor
    Patent number: 8338135
    Abstract: An isolated human antibody or antigen binding fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4R?) with an affinity constant (KD) of less than 200 pM, as measured by surface plasmon resonance, is provided.
    Type: Grant
    Filed: December 2, 2011
    Date of Patent: December 25, 2012
    Assignee: Regeneron Pharmaceuticals, inc.
    Inventors: Sean Stevens, Tammy T. Huang, Joel H. Martin, Jeanette L. Fairhurst, Ashique Rafique, Marcela Torres, Kevin J. Pobursky, Raymond W. Leidich, Joan A. Windsor, Warren R. Mikulka, Diana M. Ahrens, Ergang Shi, Nicholas J. Papadopoulos
  • HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN IL-4 RECEPTOR
    Publication number: 20120135010
    Abstract: An isolated human antibody or antigen binding fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4R?) with an affinity constant (KD) of less than 200 pM, as measured by surface plasmon resonance, is provided.
    Type: Application
    Filed: December 2, 2011
    Publication date: May 31, 2012
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Sean Stevens, Tammy T. Huang, Joel H. Martin, Jeanette L. Fairhurst, Ashique Rafique, Marcela Torres, Kevin J. Pobursky, Raymond W. Leidich, Joan A. Windsor, Warren R. Mikulka, Diana M. Ahrens, Ergang Shi, Nicholas J. Papadopoulos
  • High affinity human antibodies to human IL-18 receptor
    Patent number: 8105805
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Grant
    Filed: July 18, 2011
    Date of Patent: January 31, 2012
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Tammy H. Huang, Sean Stevens, Joel H. Martin, Jeanette L. Fairhurst, Kevin J. Pobursky, Margaret Karow, Joan A. Windsor, Warren R. Mikluka
  • High affinity human antibodies to human IL-4 receptor
    Patent number: 8092802
    Abstract: The present invention provides methods for treating one or more diseases or disorders which are improved, inhibited or ameliorated by reducing interleukin-4 (IL-4) activity. The methods of the invention comprise administering to a patient an antibody, or antigen-binding fragment thereof, which specifically binds to a human IL-4 receptor.
    Type: Grant
    Filed: June 23, 2010
    Date of Patent: January 10, 2012
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Sean Stevens, Tammy T. Huang, Joel H. Martin, Jeanette L. Fairhurst, Ashique Rafique, Marcela Torres, Kevin J. Pobursky, Raymond W. Leidich, Joan A. Windsor, Warren R. Mikulka, Diana M. Ahrens, Ergang Shi, Nicholas J. Papadopoulos
  • High Affinity Human Antibodies to Human IL-18 Receptor
    Publication number: 20110269187
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Application
    Filed: July 18, 2011
    Publication date: November 3, 2011
    Applicant: REGENERON PHARMACEUTICALS, INC.
    Inventors: TAMMY H. HUANG, SEAN STEVENS, JOEL H. MARTIN, JEANETTE L. FAIRHURST, KEVIN J. POBURSKY, MARGARET KAROW, JOAN A. WINDSOR, WARREN R. MIKLUKA
  • High affinity human antibodies to human IL-18 receptor
    Patent number: 8003103
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Grant
    Filed: October 13, 2009
    Date of Patent: August 23, 2011
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Tammy H. Huang, Sean Stevens, Joel H. Martin, Jeanette L. Fairhurst, Kevin J. Pobursky, Margaret Karow, Joan A. Windsor, Warren R. Mikulka
  • HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN IL-4 RECEPTOR
    Publication number: 20100291107
    Abstract: The present invention provides methods for treating one or more diseases or disorders which are improved, inhibited or ameliorated by reducing interleukin-4 (IL-4) activity. The methods of the invention comprise administering to a patient an antibody, or antigen-binding fragment thereof, which specifically binds to a human IL-4 receptor.
    Type: Application
    Filed: June 23, 2010
    Publication date: November 18, 2010
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Sean Stevens, Tammy T. Huang, Joel H. Martin, Jeanette L. Fairhurst, Ashique Rafique, Marcela Torres, Kevin J. Pobursky, Raymond W. Leidich, Joan A. Windsor, Warren R. Mikulka, Diana M. Ahrens, Ergang Shi, Nicholas J. Papadopoulos
  • High affinity human antibodies to human IL-4 receptor
    Patent number: 7794717
    Abstract: The present invention provides methods for treating one or more diseases or disorders which are improved, inhibited or ameliorated by reducing interleukin-4 (IL-4) activity. The methods of the invention comprise administering to a patient an antibody, or antigen-binding fragment thereof, which specifically binds to a human IL-4 receptor.
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: September 14, 2010
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Sean Stevens, Tammy T. Huang, Joel H. Martin, Jeanette L. Fairhurst, Ashique Rafique, Marcela Torres, Kevin J. Pobursky, Raymond W. Leidich, Joan A. Windsor, Warren R. Mikulka, Diana M. Ahrens, Ergang Shi, Nicholas J. Papadopoulos
  • HIGH AFFINITY HUMAN ANTIBODIES TO HUMAN IL-18 RECEPTOR
    Publication number: 20100034833
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Application
    Filed: October 13, 2009
    Publication date: February 11, 2010
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Tammy H. Huang, Sean Stevens, Joel H. Martin, Jeanette L. Fairhurst, Kevin J. Pobursky, Margaret Karow, Joan A. Windsor, Warren R. Mikulka
  • High Affinity Human Antibodies to Human IL-4 Receptor
    Publication number: 20100021476
    Abstract: The present invention provides methods for treating one or more diseases or disorders which are improved, inhibited or ameliorated by reducing interleukin-4 (IL-4) activity. The methods of the invention comprise administering to a patient an antibody, or antigen-binding fragment thereof, which specifically binds to a human IL-4 receptor.
    Type: Application
    Filed: September 4, 2009
    Publication date: January 28, 2010
    Applicant: Regeneron Pharmaceuticals, Inc.
    Inventors: Sean Stevens, Tammy T. Huang, Joel H. Martin, Jeanette L. Fairhurst, Ashique Rafique, Marcela Torres, Kevin J. Pobursky, Raymond W. Leidich, Joan A. Windsor, Warren R. Mikulka, Diana M. Ahrens, Ergang Shi, Nicholas J. Papadopoulos
  • High affinity human antibodies to human IL-18 receptor
    Patent number: 7615220
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: November 10, 2009
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Tammy H. Huang, Sean Stevens, Joel H. Martin, Jeanette L. Fairhurst, Kevin J. Pobursky, Margaret Karow, Joan A. Windsor, Warren R. Mikulka
  • High affinity human antibodies to human IL-4 receptor
    Patent number: 7605237
    Abstract: An isolated human antibody or antibody fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4R?) with an affinity constant (KD) of less than 200 pM, as measured by surface plasmon resonance.
    Type: Grant
    Filed: October 2, 2007
    Date of Patent: October 20, 2009
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Sean Stevens, Tammy T. Huang, Joel H. Martin, Jeanette L. Fairhurst, Ashique Rafique, Marcela Torres, Kevin J. Pobursky, Raymond W. Leidich, Joan A. Windsor, Warren R. Mikulka, Diana M. Ahrens, Ergang Shi, Nicholas J. Papadopoulos
  • High affinity human antibodies to human IL-4 receptor
    Publication number: 20080160035
    Abstract: An isolated human antibody or antibody fragment thereof which binds to human interleukin-4 receptor alpha (hIL-4R?) with an affinity constant (KD) of less than 200 pM, as measured by surface plasmon resonance.
    Type: Application
    Filed: October 2, 2007
    Publication date: July 3, 2008
    Inventors: Sean Stevens, Tammy T. Huang, Joel H. Martin, Jeanette L. Fairhurst, Ashique Rafique, Marcela Torres, Kevin J. Pobursky, Raymond W. Leidich, Joan A. Windsor, Warren R. Mikulka, Dina M. Ahrens, Ergang Shi, Nicholas J. Papadopoulos
  • High affinity human antibodies to human IL-18 receptor
    Publication number: 20070237776
    Abstract: An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18R?), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
    Type: Application
    Filed: April 6, 2007
    Publication date: October 11, 2007
    Inventors: Tammy Huang, Sean Stevens, Joel Martin, Jeanette Fairhurst, Kevin Pobursky, Margaret Karow, Joan Windsor, Warren Mikulka