Patents by Inventor Joan M. Zakel

Joan M. Zakel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Immunological detection of RNA:DNA hybrids on microarrays
    Patent number: 7399589
    Abstract: The present invention provides a hybridization method and kit for the detection and measurement of biological molecules. A test sample containing the biological molecules of interest is hybridized with an unlabeled or optionally a detectably-labeled complementary biomolecule to form a double-stranded hybrid immobilized to a solid phase. The immobilized hybrid may be detected with an entity which specifically recognizes an RNA:DNA hybrid, followed by analyses and quantification. Therefore, the present invention provides a method and kit to detect and measure biological molecules that is simple to use, highly specific, sensitive, and accurate for screening a plurality of biological molecules.
    Type: Grant
    Filed: December 11, 2003
    Date of Patent: July 15, 2008
    Assignee: Digene Corporation
    Inventors: James G. Lazar, Joan M. Zakel, Christina M. Strange, Inna R. Williams, Attila T. Lorincz, Abel De La Rosa
  • Immunological detection of RNA:DNA hybrids on microarrays
    Publication number: 20040180362
    Abstract: The present invention provides a hybridization method and kit for the detection and measurement of biological molecules. A test sample containing the biological molecules of interest is hybridized with an unlabeled or optionally a detectably-labeled complementary biomolecule to form a double-stranded hybrid immobilized to a solid phase. The immobilized hybrid may be detected with an entity which specifically recognizes an RNA:DNA hybrid, followed by analyses and quantification. Therefore, the present invention provides a method and kit to detect and measure biological molecules that is simple to use, highly specific, sensitive, and accurate for screening a plurality of biological molecules.
    Type: Application
    Filed: December 11, 2003
    Publication date: September 16, 2004
    Inventors: James G. Lazar, Joan M. Zakel, Christina M. Strange, Inna R. Williams, Attila T. Lorincz, Abel De La Rosa
  • Immunological detection of RNA:DNA hybrids on microarrays
    Patent number: 6686151
    Abstract: The present invention provides a hybridization method and kit for the detection and measurement of biological molecules. A test sample containing the biological molecules of interest is hybridized with an unlabeled or optionally a detectably labeled complementary biomolecule to form a double-stranded hybrid immobilized to a solid phase. The immobilized hybrid may be detected with an entity which specifically recognizes an RNA:DNA hybrid, followed by analyses and quantification. Therefore, the present invention provides a method and kit to detect and measure biological molecules that is simple to use, highly specific, sensitive, and accurate for screening a plurality of biological molecules.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: February 3, 2004
    Assignee: Digene Corporation
    Inventors: James G. Lazar, Joan M. Zakel, Christina M. Strange, Inna R. Williams, Attila T. Lorincz, Abel De La Rosa