Patents by Inventor Joan Steitz

Joan Steitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Fluorescence amplification method for forward genetic discovery of factors in human mRNA degradation
    Patent number: 11060153
    Abstract: The present invention provides systems and methods for performing forward genetic screens in cells and methods of treating disease through inhibiting targets identified in a forward genetic screen as involved in a pathway associated with the disease. The invention involves the use of multiple tandem fluorescent reporter molecules separated by cleavage sites under the control of a single promoter to enhance the fluorescent readout from a cell screen.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: July 13, 2021
    Assignee: Yale University
    Inventors: Andrei Alexandrov, Joan Steitz
  • Fluorescence Amplification Method for Forward Genetic Discovery of Factors in Human mRNA Degradation
    Publication number: 20180179601
    Abstract: The present invention provides systems and methods for performing forward genetic screens in cells and methods of treating disease through inhibiting targets identified in a forward genetic screen as involved in a pathway associated with the disease. The invention involves the use of multiple tandem fluorescent reporter molecules separated by cleavage sites under the control of a single promoter to enhance the fluorescent readout from a cell screen.
    Type: Application
    Filed: December 21, 2017
    Publication date: June 28, 2018
    Inventors: Andrei Alexandrov, Joan Steitz