Patents by Inventor Joan W. Berman

Joan W. Berman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Cellular targets for HIV infection
    Patent number: 9540646
    Abstract: Methods and compositions are provided for treating HIV infection and for inhibiting HIV infection, and for identifying purinergic receptor antagonists or Panx 1 hemi-channel blockers useful therefor. The invention provides a method of treating a mammalian subject having an HIV infection, or suspected of having been exposed to HIV, comprising administering to the mammalian subject an amount of (i) an antagonist of a Panx 1 hemichannel, or (ii) of an inhibitor of a purinergic receptor, effective to inhibit (a) HIV fusion with a target cell, or (b) HIV replication, or (c) HIV entry into a target cell, or two or more of (a), (b) and (c).
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: January 10, 2017
    Assignee: Albert Einstein College of Medicine, Inc.
    Inventors: Eliseo Eugenin, Joan W. Berman
  • NOVEL CELLULAR TARGETS FOR HIV INFECTION
    Publication number: 20150057331
    Abstract: Methods and compositions are provided for treating HIV infection and for inhibiting HIV infection, and for identifying purinergic receptor antagonists or Panx 1 hemi-channel blockers useful therefor. The invention provides a method of treating a mammalian subject having an HIV infection, or suspected of having been exposed to HIV, comprising administering to the mammalian subject an amount of (i) an antagonist of a Panx 1 hemichannel, or (ii) of an inhibitor of a purinergic receptor, effective to inhibit (a) HIV fusion with a target cell, or (b) HIV replication, or (c) HIV entry into a target cell, or two or more of (a), (b) and (c).
    Type: Application
    Filed: February 28, 2013
    Publication date: February 26, 2015
    Applicant: ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY
    Inventors: Eliseo Eugenin, Joan W. Berman
  • Monocyte adhesion protein and monoclonal antibody thereto
    Patent number: 5541296
    Abstract: This invention relates to a method for the prevention of monocyte adherence to the endothelial cells lining blood vessels, their subsequent invasion of surrounding tissues and diseases related thereto. It comprises inducing a monocyte adhesion protein to the surface of endothelial cells by treatment with specific cytokines, preparing a monoclonal antibody to the monocyte adhesion protein and contacting the antibody to the protein to form a complex. The monoclonal antibody does not bind to the cell surface proteins VCAM or ELAM. The complex results in a decrease in the adherence of monocytes to endothelial cells and thereby attenuates or prevents the harmful effects of monocyte invasion of endothelial cells and surrounding tissues.
    Type: Grant
    Filed: December 16, 1994
    Date of Patent: July 30, 1996
    Assignee: Albert Einstein College of Medicine of Yeshiva University, a Division of Yeshiva University
    Inventors: Joan W. Berman, Tina M. Calderon