Patents by Inventor Joan Zeltinger
Joan Zeltinger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8128924Abstract: The present invention relates to a method for promoting blood vessel formation in tissues and organs. In particular, the method relates to implantation or attachment of an engineered three-dimensional stromal tissue to promote endothelialization and angiogenesis in the heart and related tissues. The three-dimensional stromal tissue of the present invention may be used in a variety of applications including, but not limited to, promoting repair of and regeneration of damaged cardiac muscle, promoting vascularization and healing during cardiac surgery, promoting blood vessel formation at anastomosis sites, and promoting vascularization and repair of damaged skeletal muscle, smooth muscle or connective tissue.Type: GrantFiled: April 8, 2009Date of Patent: March 6, 2012Assignee: Theregen, Inc.Inventors: Gail K. Naughton, Jonathan Noel Mansbridge, Robert Emmett Pinney, Joan Zeltinger
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Patent number: 8124700Abstract: Inherently radiopaque side-chain crystallizable polymers (IRSCCP's) are useful in various medical applications. An example of a IRSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer, the heavy atoms being present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes a IRSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product.Type: GrantFiled: May 5, 2011Date of Patent: February 28, 2012Assignee: REVA Medical, Inc.Inventors: Donald K Brandom, Joan Zeltinger, Eric V Schmid, Joseph J Mallon
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Publication number: 20110213470Abstract: The present invention relates to a method for promoting blood vessel formation in tissues and organs. In particular, the method relates to implantation or attachment of an engineered three-dimensional stromal tissue to promote endothelialization and angiogenesis in the heart and related tissues. The three-dimensional stromal tissue of the present invention may be used in a variety of applications including, but not limited to, promoting repair of and regeneration of damaged cardiac muscle, promoting vascularization and healing during cardiac surgery, promoting blood vessel formation at anastomosis sites, and promoting vascularization and repair of damaged skeletal muscle, smooth muscle or connective tissue.Type: ApplicationFiled: December 29, 2010Publication date: September 1, 2011Applicant: Theregen, Inc.Inventors: Gail K. Naughton, Jonathan Noel Mansbridge, Robert Emmett Pinney, Joan Zeltinger
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Publication number: 20110213090Abstract: Inherently radiopaque side-chain crystallizable polymers (IRSCCP's) are useful in various medical applications. An example of a IRSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer, the heavy atoms being present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes a IRSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product.Type: ApplicationFiled: May 5, 2011Publication date: September 1, 2011Applicant: REVA Medical, Inc.Inventors: Donald K. Brandom, Joan Zeltinger, Eric V. Schmid, Joseph J. Mallon
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Publication number: 20110212050Abstract: Inherently radiopaque side-chain crystallizable polymers (IRSCCP's) are useful in various medical applications. An example of a IRSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer, the heavy atoms being present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes a IRSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product.Type: ApplicationFiled: May 5, 2011Publication date: September 1, 2011Applicant: REVA Medical, Inc.Inventors: Donald K. Brandom, Joan Zeltinger, Eric V. Schmid, Joseph J. Mallon
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Publication number: 20110213456Abstract: Side-chain crystallizable (SCC) polymers are useful in various medical applications. In certain applications, heavy atom containing side-chain crystallizable polymers (HACSCCP's) are particularly useful. An example of a HACSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer. In certain configurations, the heavy atoms are present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes an HACSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product. A polymeric material that includes a SCC polymer may also be fabricated into other medical devices, such as stents.Type: ApplicationFiled: May 5, 2011Publication date: September 1, 2011Applicant: REVA Medical, Inc.Inventors: Donald K. Brandom, James E. McGrath, Joan Zeltinger, Eric V. Schmid, Robert K. Schultz
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Patent number: 7939611Abstract: Inherently radiopaque side-chain crystallizable polymers (IRSCCP's) are useful in various medical applications. An example of a IRSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer, the heavy atoms being present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes a IRSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product.Type: GrantFiled: July 7, 2005Date of Patent: May 10, 2011Assignee: REVA Medical, Inc.Inventors: Donald K. Brandom, Joan Zeltinger, Eric V. Schmid, Joseph J. Mallon
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Publication number: 20100131037Abstract: The present invention relates to polymeric medical devices such as stents. More particularly the polymeric compositions disclosed herein comprise halogen-containing, tyrosine-derived diphenols, optionally in conjunction with other groups, such as dicarboxylic acids and/or poly(alkylene oxides), such that the medical devices made from these polymeric compositions are bioresorbable and inherently radiopaque, and exhibit physicomechanical properties consistent with the intended uses of such devices.Type: ApplicationFiled: September 24, 2009Publication date: May 27, 2010Applicant: Rutgers , the State UniversityInventors: Joachim B. Kohn, Durgadas Bolikal, Aaron D. Pesnell, Joan Zeltinger, Donald K. Brandom, Eric Schmid
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Patent number: 7722662Abstract: The present invention provides a lumen support stent with a clear through-lumen for use in a body lumen. The stent is formed from at least one series of sliding and locking radial elements and at least one ratcheting mechanism comprising an articulating element and a plurality of stops. The ratcheting mechanism permits one-way sliding of the radial elements from a collapsed diameter to an expanded diameter, but inhibits radial recoil from the expanded diameter.Type: GrantFiled: October 13, 2006Date of Patent: May 25, 2010Assignee: REVA Medical, Inc.Inventors: Thomas A. Steinke, Donald H. Koenig, Joan Zeltinger
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Publication number: 20090269316Abstract: The present invention relates to a method for promoting blood vessel formation in tissues and organs. In particular, the method relates to implantation or attachment of an engineered three-dimensional stromal tissue to promote endothelialization and angiogenesis in the heart and related tissues. The three-dimensional stromal tissue of the present invention may be used in a variety of applications including, but not limited to, promoting repair of and regeneration of damaged cardiac muscle, promoting vascularization and healing during cardiac surgery, promoting blood vessel formation at anastomosis sites, and promoting vascularization and repair of damaged skeletal muscle, smooth muscle or connective tissue.Type: ApplicationFiled: April 8, 2009Publication date: October 29, 2009Applicant: Theregen, Inc.Inventors: Gail K. Naughton, Jonathan Noel Mansbridge, Robert Emmett Pinney, Joan Zeltinger
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Publication number: 20090123503Abstract: Novel products comprising conditioned cell culture medium compositions and methods of use are described. The conditioned cell medium compositions of the invention may be comprised of any known defined or undefined medium and may be conditioned using any eukaryotic cell type. The medium may be conditioned by stromal cells, parenchymal cells, mesenchymal stem cells, liver reserve cells, neural stem cells, pancreatic stem cells and/or embryonic stem cells. Additionally, the cells may be genetically modified. A three-dimensional tissue construct is preferred. Once the cell medium of the invention is conditioned, it may be used in any state. Physical embodiments of the conditioned medium include, but are not limited to, liquid or solid, frozen, lyophilized or dried into a powder.Type: ApplicationFiled: January 6, 2009Publication date: May 14, 2009Applicant: SkinMedica. Inc.Inventors: Gail K. Naughton, David L. Horwitz, Mark A. Applegate, Joan Zeltinger, Jonathan N. Mansbridge, Andreas Kern, Lee K. Landeen, Anthony Ratcliffe, R. Emmett Pinney
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Patent number: 7473417Abstract: Preferred embodiments of the present invention relate to polymeric medical devices, such as stents. More particularly, the compositions disclosed herein comprise halogen-containing phenol moeities, that may be used for medical devices and other uses whereby bioresorbable and radiopaque and physicomechanical properties are desired.Type: GrantFiled: August 10, 2005Date of Patent: January 6, 2009Assignee: REVA Medical, Inc.Inventors: Joan Zeltinger, Donald K. Brandom
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Publication number: 20070142901Abstract: In preferred embodiments, this invention relates to an expandable stent, comprising a tubular member comprising at least two circumferentially-adjacent radial elements, wherein each radial element comprises an engagement slot, through which a portion of the circumferentially-adjacent radial element is slidably engaged, such that the tubular member is capable of expanding from a first collapsed diameter to a second expanded diameter, wherein the engagement slot is not a paired slot.Type: ApplicationFiled: February 28, 2007Publication date: June 21, 2007Inventors: Thomas Steinke, Donald Koenig, Joan Zeltinger
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Publication number: 20070077232Abstract: Novel products comprising conditioned cell culture medium compositions and methods of use are described. The conditioned cell medium compositions of the invention may be comprised of any known defined or undefined medium and may be conditioned using any eukaryotic cell type. The medium may be conditioned by stromal cells, parenchymal cells, mesenchymal stem cells, liver reserve cells, neural stem cells, pancreatic stem cells and/or embryonic stem cells. Additionally, the cells may be genetically modified. A three-dimensional tissue construct is preferred. Once the cell medium of the invention is conditioned, it may be used in any state. Physical embodiments of the conditioned medium include, but are not limited to, liquid or solid, frozen, lyophilized or dried into a powder.Type: ApplicationFiled: October 3, 2006Publication date: April 5, 2007Applicant: SkinMedica, Inc.Inventors: Gail Naughton, David Horwitz, Mark Applegate, Joan Zeltinger, Jonathan Mansbridge, Andreas Kern, Lee Landeen, Anthony Ratcliffe, R. Pinney
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Publication number: 20070061004Abstract: The present invention provides a lumen support stent with a clear through-lumen for use in a body lumen. The stent is formed from at least one series of sliding and locking radial elements and at least one ratcheting mechanism comprising an articulating element and a plurality of stops. The ratcheting mechanism permits one-way sliding of the radial elements from a collapsed diameter to an expanded diameter, but inhibits radial recoil from the expanded diameter.Type: ApplicationFiled: October 13, 2006Publication date: March 15, 2007Inventors: Thomas Steinke, Donald Koenig, Joan Zeltinger
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Patent number: 7118746Abstract: Novel products comprising conditioned cell culture medium compositions and methods of use are described. The conditioned cell medium compositions of the invention may be comprised of any known defined or undefined medium and may be conditioned using any eukaryotic cell type. The medium may be conditioned by stromal cells, parenchymal cells, mesenchymal stem cells, liver reserve cells, neural stem cells, pancreatic stem cells and/or embryonic stem cells. Additionally, the cells may be genetically modified. A three-dimensional tissue construct is preferred. Once the cell medium of the invention is conditioned, it may be used in any state. Physical embodiments of the conditioned medium include, but are not limited to, liquid or solid, frozen, lyophilized or dried into a powder.Type: GrantFiled: May 12, 2000Date of Patent: October 10, 2006Assignee: SkinMedica, Inc.Inventors: Gail K. Naughton, David L. Horwitz, Mark A. Applegate, Joan Zeltinger, Jonathan N. Mansbridge, Andreas Kern, Lee K. Landeen, Anthony Ratcliffe, R. Emmett Pinney
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Publication number: 20060182779Abstract: Side-chain crystallizable (SCC) polymers are useful in various medical applications. In certain applications, heavy atom containing side-chain crystallizable polymers (HACSCCP's) are particularly useful. An example of a HACSCCP is a polymer that comprises a main chain, a plurality of crystallizable side chains, and a plurality of heavy atoms attached to the polymer. In certain configurations, the heavy atoms are present in an amount that is effective to render the polymer radiopaque. A polymeric material that includes an HACSCCP may be fabricated into a medical device useful for at least partially occluding a body cavity. For example, such a medical device may be an embolotherapy product. A polymeric material that includes a SCC polymer may also be fabricated into other medical devices, such as stents.Type: ApplicationFiled: January 18, 2006Publication date: August 17, 2006Inventors: Donald Brandom, James McGrath, Joan Zeltinger, Eric Schmid, Robert Schultz
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Publication number: 20060136041Abstract: The invention relates to an expandable stent comprising circumferentially adjacent modules. The modules comprise longitudinally adjacent slide-and-lock radial elements which permit one-way sliding of the radial elements from a collapsed diameter to an expanded/deployed diameter, but inhibit radial recoil from the expanded diameter.Type: ApplicationFiled: December 17, 2004Publication date: June 22, 2006Inventors: Eric Schmid, John Nguyen, Steven Howard, Orlando Padilla, Andrew Morris, Robert Eisele, Joseph DiPari, David Matsuura, Philip Simpson, Walter Gillespie, Daniel Moore, Thomas Jackson, Joan Zeltinger, Keith Esser, Donald Brandon
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Publication number: 20060036316Abstract: Preferred embodiments of the present invention relate to polymeric medical devices, such as stents. More particularly, the compositions disclosed herein comprise halogen-containing phenol moeities, that may be used for medical devices and other uses whereby bioresorbable and radiopaque and physicomechanical properties are desired.Type: ApplicationFiled: August 10, 2005Publication date: February 16, 2006Inventors: Joan Zeltinger, Donald Brandom
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Publication number: 20060034769Abstract: Preferred embodiments of the present invention relate to polymeric medical devices, such as stents. More particularly, the polymeric compositions disclosed herein comprise halogen-containing, tyrosine-derived diphenols, optionally in conjunction with other groups, such as dicarboxylic acids and/or poly(alkylene oxide), such that the medical devices made from these polymeric compositions are bioresorbable and inherently radiopaque, and exhibit physicomechanical properties consistent with the intended uses of such devices.Type: ApplicationFiled: September 27, 2004Publication date: February 16, 2006Applicant: Rutgers, The State UniversityInventors: Joachim Kohn, Durgadas Bolikal, Aaron Pesnell, Joan Zeltinger, Donald Brandom, Eric Schmid