Patents by Inventor Joana Baptista

Joana Baptista has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of tamsulosin and intermediates thereof
    Patent number: 8017803
    Abstract: A process for producing tamsulosin of formula I and pharmaceutically acceptable addition salts, thereof comprises the steps of: a) Reacting compound R,R-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-(1-phenyl-ethyl)-amine of formula II or a salt thereof ?with chlorosulfonic acid with or without an organic solvent, to obtain compound R,R-2-methoxy-5-[2-(1-phenyl-ethylamino)-propyl]-benzenesulfonic acid of formula III b) Hydrogenolysis of compound R,R-2-methoxy-5-[2-(1-phenyl-ethylamino)-propyl]-benzenesulfonic acid of formula III or a salt thereof carried out in an alcohol in the presence of a palladium catalyst using hydrogen or a source of hydrogen, to obtain compound R-(?)-5-(2-amino-propyl)-2-methoxy-benzenesulfonic acid of formula IV c) Reacting primary amine R-(?)-5-(2-amino-propyl)-2-methoxy-benzenesulfonic acid of formula IV, or a salt thereof, with a compound of formula V ?wherein X represents an halogen atom selected from the group consisting of Cl; Br and I, to obtain 5-{(2R)-2-
    Type: Grant
    Filed: January 18, 2005
    Date of Patent: September 13, 2011
    Assignee: Hovione Inter Ltd.
    Inventors: Zita Mendes, Joana Baptista, Dionisio Martin, William Heggie
  • Process for the Preparation of Biphosphonic Acids and Salts Thereof
    Publication number: 20090326227
    Abstract: A process for the preparation of biphosphonic acids and pharmaceutical acceptable salts thereof, comprises reacting a carboxylic acid with phosphorous trichloride and phosphorous acid in the presence of an aprotic polar solvent.
    Type: Application
    Filed: November 6, 2007
    Publication date: December 31, 2009
    Applicant: HOVIONE INTER LIMITED
    Inventors: Joana Baptista, Zita Mendes
  • Process for the preparation of tamsulosin and intermediates thereof
    Publication number: 20090234154
    Abstract: A process for producing tamsulosin of formula I and pharmaceutically acceptable addition salts, thereof comprises the steps of: a) Reacting compound R,R-[2-(4-methoxy-phenyl)-1-methyl-ethyl]-(1-phenyl-ethyl)-amine of formula II or a salt thereof ?with chlorosulfonic acid with or without an organic solvent, to obtain compound R,R-2-methoxy-5-[2-(1-phenyl-ethylamino)-propyl]-benzenesulfonic acid of formula III b) Hydrogenolysis of compound R,R-2-methoxy-5-[2-(1-phenyl-ethylamino)-propyl]-benzenesulfonic acid of formula III or a salt thereof carried out in an alcohol in the presence of a palladium catalyst using hydrogen or a source of hydrogen, to obtain compound R-(?)-5-(2-amino-propyl)-2-methoxy-benzenesulfonic acid of formula IV c) Reacting primary amine R-(?)-5-(2-amino-propyl)-2-methoxy-benzenesulfonic acid of formula IV, or a salt thereof, with a compound of formula V ?wherein X represents an halogen atom selected from the group consisting of Cl; Br and I, to obtain 5-{(2R)-2-
    Type: Application
    Filed: January 18, 2005
    Publication date: September 17, 2009
    Inventors: Zita Mendes, Joana Baptista, Dionisio Martin, William Heggie
  • Dial
    Patent number: D778197
    Type: Grant
    Filed: January 19, 2016
    Date of Patent: February 7, 2017
    Assignee: SWATCH LTD
    Inventor: Joana Baptista Vasconcelos