Patents by Inventor Joane Litvak

Joane Litvak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions comprising a substituted benzimidazole useful for treating immunomediated inflammatory disorders
    Patent number: 6562854
    Abstract: Novel compounds, compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders are described. The compounds, compositions and methods are effective for the prevention and treatment of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis, as well as other types of immunomediated inflammatory disorders, such as rheumatoid arthritis, conjunctivitis and inflammatory bowel disease, various dermatological conditions, as well as certain viral conditions. The compounds comprise potent and selective inhibitors of the mast cell protease tryptase. The compositions for treating these conditions include oral, inhalant, topical and parenteral preparations as well as devices comprising such preparations.
    Type: Grant
    Filed: June 4, 2001
    Date of Patent: May 13, 2003
    Assignee: Axys Pharmaceuticals, Inc.
    Inventors: Timothy J. Church, Neil Scott Cutshall, Anthony R. Gangloff, Thomas E. Jenkins, Martin S. Linsell, Joane Litvak, Kenneth D. Rice, Jeffrey R. Spencer, Vivian R. Wang
  • Substituted 1, 4-thiazepine and analogs as activators of caspases and inducers of apoptosis and the use thereof
    Publication number: 20020010169
    Abstract: The present invention is directed to substituted 1,4-thiazepine and analogs thereof, represented by the general Formula I: 1
    Type: Application
    Filed: April 18, 2001
    Publication date: January 24, 2002
    Applicant: Cytovia, Inc.
    Inventors: John A. Drewe, Sui Xiong Cai, Emma Jane Shelton, Joane Litvak, David Sperandio, Jeffrey R. Spencer
  • Novel compounds and compositions for treating diseases asociated with protease activity
    Publication number: 20010053779
    Abstract: Novel compounds, compositions and methods effective for the prevention and treatment of mast-cell mediated inflammatory disorders are described. The compounds, compositions and methods are effective for the prevention and treatment of inflammatory diseases associated with the respiratory tract, such as asthma and allergic rhinitis, as well as other types of immunomediated inflammatory disorders, such as rheumatoid arthritis, conjunctivitis and inflammatory bowel disease, various dermatological conditions, as well as certain viral conditions. The compounds comprise potent and selective inhibitors of the mast cell protease tryptase. The compositions for treating these conditions include oral, inhalant, topical and parenteral preparations as well as devices comprising such preparations.
    Type: Application
    Filed: June 4, 2001
    Publication date: December 20, 2001
    Inventors: Timothy J. Church, Neil Scott Cutshall, Anthony R. Gangloff, Thomas E. Jenkins, Martin S. Linsell, Joane Litvak, Kenneth D. Rice, Jeffrey R. Spencer, Vivian R. Wang
  • 1,2-dithiins having antifungal activity
    Patent number: 5648354
    Abstract: Novel 1,2-dithiin compounds useful as antifungal or anti-infective agents, as well as methods for their use as such, are described.
    Type: Grant
    Filed: February 28, 1995
    Date of Patent: July 15, 1997
    Assignee: Shaman Pharmaceuticals, Inc.
    Inventors: Donald E. Bierer, Jeffrey M. Dener, Joane Litvak, Larisa G. Dubenko