Patents by Inventor Jo Ann Hoskins
Jo Ann Hoskins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6271000Abstract: The invention provides isolated nucleic acid compounds encoding enzyme mraY of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded enzyme, and a method for identifying compounds that inhibit said enzyme.Type: GrantFiled: December 8, 1997Date of Patent: August 7, 2001Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Robert Brown Peery, Paul Luther Skatrud, Michele Louise Young Bellido
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Patent number: 6268175Abstract: The invention provides isolated nucleic acid compounds encoding gcp of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.Type: GrantFiled: December 8, 1997Date of Patent: July 31, 2001Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Joseph Chiou-Chung Tang, Patti Jean Treadway
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Patent number: 6171834Abstract: The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.Type: GrantFiled: April 30, 1999Date of Patent: January 9, 2001Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Franklin Harpold Norris, Pamela Kay Rockey, Paul Robert Rosteck, Jr., Paul Luther Skatrud, Patti Jean Treadway, Michele Louise Young Bellido, Chyun-Yeh Earnest Wu
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Patent number: 6162617Abstract: The invention provides isolated nucleic acid compounds encoding dnaG of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.Type: GrantFiled: December 8, 1997Date of Patent: December 19, 2000Assignee: Eli Lilly and CompanyInventors: Stanley Gene Burgett, Jo Ann Hoskins, Stanley Richard Jaskunas, Jr., Robert Brown Peery, Paul Robert Rosteck, Jr., Genshi Zhao
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Patent number: 6143868Abstract: The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the MTG.Type: GrantFiled: April 9, 1998Date of Patent: November 7, 2000Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Stanley R. Jaskunas, Jr., Robert B. Peery, Paul L. Skatrud
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Patent number: 5981281Abstract: Provided herein is a method to produce knockout mutations at targeted sites in the genome of Streptococcus pneumoniae.Type: GrantFiled: December 8, 1997Date of Patent: November 9, 1999Assignee: Eli Lilly and CompanyInventors: Richard Henry Baltz, Jo Ann Hoskins, Patricia Jean Solenberg, Patti Jean Treadway
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Patent number: 5948645Abstract: The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.Type: GrantFiled: December 4, 1996Date of Patent: September 7, 1999Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Franklin Harpold Norris, Pamela Kay Rockey, Paul Robert Rosteck, Jr., Paul Luther Skatrud, Patti Jean Treadway, Michele Louise Young Bellido, Chyun-Yeh Earnest Wu
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Patent number: 5922540Abstract: The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the MTG.Type: GrantFiled: December 20, 1996Date of Patent: July 13, 1999Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Stanley R. Jaskunas, Jr., Robert B. Peery, Paul L. Skatrud
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Patent number: 5834270Abstract: The invention provides isolated nucleic acid compounds encoding the murD stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurD enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.Type: GrantFiled: April 14, 1997Date of Patent: November 10, 1998Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Robert Brown Peery, Paul Luther Skatrud, Chyun-Yeh Earnest Wu
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Patent number: 5821335Abstract: The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murG of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurG enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.Type: GrantFiled: November 19, 1996Date of Patent: October 13, 1998Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Paul Luther Skatrud, Robert Brown Peery
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Patent number: 5789202Abstract: The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.Type: GrantFiled: October 17, 1996Date of Patent: August 4, 1998Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, S. Richard Jaskunas, Jr., Pamela K. Rockey, Paul R. Rosteck, Jr., Franklin H. Norris
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Patent number: 5710018Abstract: The present invention provides isolated DNA compounds and recombinant DNA vectors that encode mammalian influx peptide transporter activity. The invention also provides host cells transformed with these vectors and a method for production of mammalian influx peptide transporter activity by recombinant DNA techniques. The invention also provides a method for identifying compounds that are transported into the cell by the influx peptide transporter.Type: GrantFiled: June 5, 1995Date of Patent: January 20, 1998Assignee: Eli Lilly and CompanyInventors: Anne H. Dantzig, Jo Ann Hoskins, Paul L. Skatrud
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Patent number: 5681694Abstract: The invention provides isolated nucleic acid compounds encoding the murD stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurD enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.Type: GrantFiled: June 18, 1996Date of Patent: October 28, 1997Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Robert Brown Peery, Paul Luther Skatrud, Chyun-Yeh Earnest Wu
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Patent number: H2023Abstract: The invention provides isolated nucleic acid compounds encoding GrpE of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.Type: GrantFiled: December 8, 1997Date of Patent: May 7, 2002Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Stanley Richard Jaskunas, Jr., Pamela Kay Rockey, Patti Jean Treadway
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Patent number: H2070Abstract: The invention provides isolated nucleic acid compounds encoding a DNA ligase of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.Type: GrantFiled: December 8, 1997Date of Patent: July 1, 2003Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, Stanley Richard Jaskunas, Jr., Timothy Ivan Meier, Pamela Kay Rockey, Genshi Zhao
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Patent number: H2085Abstract: The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.Type: GrantFiled: January 28, 1998Date of Patent: October 7, 2003Assignee: Eli Lilly and CompanyInventors: Jo Ann Hoskins, S. Richard Jaskunas, Jr., Genshi Zhao, Pamela K. Rockey, Paul R. Rosteck, Jr., Franklin H. Norris