Patents by Inventor Jo Ann Hoskins

Jo Ann Hoskins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6271000
    Abstract: The invention provides isolated nucleic acid compounds encoding enzyme mraY of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded enzyme, and a method for identifying compounds that inhibit said enzyme.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: August 7, 2001
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Robert Brown Peery, Paul Luther Skatrud, Michele Louise Young Bellido
  • Patent number: 6268175
    Abstract: The invention provides isolated nucleic acid compounds encoding gcp of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: July 31, 2001
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Joseph Chiou-Chung Tang, Patti Jean Treadway
  • Patent number: 6171834
    Abstract: The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
    Type: Grant
    Filed: April 30, 1999
    Date of Patent: January 9, 2001
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Franklin Harpold Norris, Pamela Kay Rockey, Paul Robert Rosteck, Jr., Paul Luther Skatrud, Patti Jean Treadway, Michele Louise Young Bellido, Chyun-Yeh Earnest Wu
  • Patent number: 6162617
    Abstract: The invention provides isolated nucleic acid compounds encoding dnaG of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: December 19, 2000
    Assignee: Eli Lilly and Company
    Inventors: Stanley Gene Burgett, Jo Ann Hoskins, Stanley Richard Jaskunas, Jr., Robert Brown Peery, Paul Robert Rosteck, Jr., Genshi Zhao
  • Patent number: 6143868
    Abstract: The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the MTG.
    Type: Grant
    Filed: April 9, 1998
    Date of Patent: November 7, 2000
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Stanley R. Jaskunas, Jr., Robert B. Peery, Paul L. Skatrud
  • Patent number: 5981281
    Abstract: Provided herein is a method to produce knockout mutations at targeted sites in the genome of Streptococcus pneumoniae.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: November 9, 1999
    Assignee: Eli Lilly and Company
    Inventors: Richard Henry Baltz, Jo Ann Hoskins, Patricia Jean Solenberg, Patti Jean Treadway
  • Patent number: 5948645
    Abstract: The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murI of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurI enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
    Type: Grant
    Filed: December 4, 1996
    Date of Patent: September 7, 1999
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Franklin Harpold Norris, Pamela Kay Rockey, Paul Robert Rosteck, Jr., Paul Luther Skatrud, Patti Jean Treadway, Michele Louise Young Bellido, Chyun-Yeh Earnest Wu
  • Patent number: 5922540
    Abstract: The invention provides isolated nucleic acid compounds encoding a novel MTG of Staphylococcus aureus. Also provided are vectors and transformed heterologous host cells for expressing the MTG and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the MTG.
    Type: Grant
    Filed: December 20, 1996
    Date of Patent: July 13, 1999
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Stanley R. Jaskunas, Jr., Robert B. Peery, Paul L. Skatrud
  • Patent number: 5834270
    Abstract: The invention provides isolated nucleic acid compounds encoding the murD stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurD enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: November 10, 1998
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Robert Brown Peery, Paul Luther Skatrud, Chyun-Yeh Earnest Wu
  • Patent number: 5821335
    Abstract: The invention provides isolated nucleic acid compounds encoding the stem peptide biosynthetic gene murG of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurG enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
    Type: Grant
    Filed: November 19, 1996
    Date of Patent: October 13, 1998
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Paul Luther Skatrud, Robert Brown Peery
  • Patent number: 5789202
    Abstract: The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.
    Type: Grant
    Filed: October 17, 1996
    Date of Patent: August 4, 1998
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, S. Richard Jaskunas, Jr., Pamela K. Rockey, Paul R. Rosteck, Jr., Franklin H. Norris
  • Patent number: 5710018
    Abstract: The present invention provides isolated DNA compounds and recombinant DNA vectors that encode mammalian influx peptide transporter activity. The invention also provides host cells transformed with these vectors and a method for production of mammalian influx peptide transporter activity by recombinant DNA techniques. The invention also provides a method for identifying compounds that are transported into the cell by the influx peptide transporter.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: January 20, 1998
    Assignee: Eli Lilly and Company
    Inventors: Anne H. Dantzig, Jo Ann Hoskins, Paul L. Skatrud
  • Patent number: 5681694
    Abstract: The invention provides isolated nucleic acid compounds encoding the murD stem peptide biosynthetic gene of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the MurD enzyme product and a method for identifying compounds that inhibit stem peptide biosynthesis.
    Type: Grant
    Filed: June 18, 1996
    Date of Patent: October 28, 1997
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Robert Brown Peery, Paul Luther Skatrud, Chyun-Yeh Earnest Wu
  • Patent number: H2023
    Abstract: The invention provides isolated nucleic acid compounds encoding GrpE of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: May 7, 2002
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Stanley Richard Jaskunas, Jr., Pamela Kay Rockey, Patti Jean Treadway
  • Patent number: H2070
    Abstract: The invention provides isolated nucleic acid compounds encoding a DNA ligase of Streptococcus pneumoniae. Also provided are vectors and transformed host cells for expressing the encoded protein, and a method for identifying compounds that bind and/or inhibit said protein.
    Type: Grant
    Filed: December 8, 1997
    Date of Patent: July 1, 2003
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, Stanley Richard Jaskunas, Jr., Timothy Ivan Meier, Pamela Kay Rockey, Genshi Zhao
  • Patent number: H2085
    Abstract: The invention provides isolated nucleic acid compounds encoding a novel high molecular weight PBP of Streptococcus pneumoniae. Also provided are vectors and transformed heterologous host cells for expressing the PBP and a method for identifying compounds that bind and/or inhibit the enzymatic activity of the PBP.
    Type: Grant
    Filed: January 28, 1998
    Date of Patent: October 7, 2003
    Assignee: Eli Lilly and Company
    Inventors: Jo Ann Hoskins, S. Richard Jaskunas, Jr., Genshi Zhao, Pamela K. Rockey, Paul R. Rosteck, Jr., Franklin H. Norris