Patents by Inventor Joanna Aizenberg

Joanna Aizenberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10385181
    Abstract: A body having a lubricant reservoir is described, comprising: a porous polymeric body; and a lubricating liquid, said lubricating liquid occupying the pores to provide a lubricated porous surface having a lubricant reservoir and a lubricant overlayer over the polymer surface. Also described herein is a system for use in the formation of a low-adhesion and low-friction surface includes a flowable precursor composition comprising a prepolymer and a curing agent, said composition capable of application as a coating over a large surface area; a lubricating liquid that is capable of forming a coating with the hardened precursor composition, wherein the lubricating liquid and hardened polymer together form a coating of lubricating liquid stabilized on and in the hardened polymer; and instructions for applying the precursor composition onto a surface for the purpose of obtaining a low-adhesion and low-friction surface.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: August 20, 2019
    Assignee: President and Fellows of Harvard College
    Inventors: Joanna Aizenberg, Michael Aizenberg, Philseok Kim, Alex Vena
  • Publication number: 20190227224
    Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.
    Type: Application
    Filed: October 19, 2018
    Publication date: July 25, 2019
    Applicants: President and Fellows of Harvard College, University of Exeter
    Inventors: Joanna AIZENBERG, Mathias KOLLE, Peter VUKUSIC, Robert D. HOWE
  • Patent number: 10330218
    Abstract: A gating mechanism that uses a capillary stabilized liquid as a reversible, reconfigurable gate that fills and seals pores in the closed state, and creates a non-fouling, liquid-lined pore in the open state is disclosed. Theoretical modeling and experiments demonstrate that for each transport substance, the gating threshold—the pressure needed to open the pores—can be rationally tuned over a wide pressure range. This enables realizing in one system differential response profiles for a variety of liquids and gases, even letting liquids flow through the pore while preventing gas from escaping. These capabilities allow dynamic modulation of gas-liquid sorting and to separate multi-phase mixtures, with the liquid lining ensuring sustained antifouling behavior.
    Type: Grant
    Filed: February 9, 2016
    Date of Patent: June 25, 2019
    Assignee: President and Fellows of Harvard College
    Inventors: Joanna Aizenberg, Xu Hou, Mughees Khan, Alexander Tesler
  • Publication number: 20190177677
    Abstract: A microfluidic device for processing cells for the intracellular delivery of molecules or other cargo includes a plurality of microchannels disposed in a substrate or chip and fluidically coupled to an inlet configured to receive a solution containing the cells and the molecules or other cargo to be delivered intracellularly to the cells. Each of the plurality of microchannels has one or more constriction regions therein, wherein the constriction regions comprise an omniphobic, superhydrophilic, or superhydrophobic surface. In some embodiments, multiple microfluidic devices operating in parallel are used to process large numbers of cells. The device and method has particularly applicability to delivering gene-editing molecules intracellularly to cells.
    Type: Application
    Filed: August 19, 2017
    Publication date: June 13, 2019
    Applicants: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, PRESIDENT AND FELLOWS OF HARVARD COLLEGE, BRIGHAM AND WOMEN'S HOSPITAL
    Inventors: Steven J. Jonas, Paul S. Weiss, Xu Hou, Joanna Aizenberg, Alireza Khademhosseini
  • Publication number: 20190136070
    Abstract: A transparent repellent, liquid-infused coating applied onto the distal end of an endoscope that prevents vision loss and reduces fouling is described. Also described is a disposable endoscope window that is coated in a transparent, repellant, liquid-infused coating for attachment to the distal end or distal window of an endoscope to obviate vision loss. Also described is an endoscope comprising a miniature camera coated in a transparent, repellent, liquid-infused coating.
    Type: Application
    Filed: April 27, 2017
    Publication date: May 9, 2019
    Applicants: President and Fellows of Harvard College, Beth Israel Deaconess Medical Center, Inc.
    Inventors: Joanna AIZENBERG, Steffi SUNNY, Nicolas VOGEL, Adnan MAJID, George CHENG, Michael AIZENBERG
  • Publication number: 20190127234
    Abstract: A co-assembly method for synthesizing inverse photonic structures is described. The method includes combining an onium compound with a sol-gel precursor to form metal oxide (MO) nanocrystals, where each MO nanocrystal has crystalline and amorphous content. The MO nanocrystals are combined with templating particles to form a suspension. A solvent is evaporated from the suspension to form an intermediate or compound product, which then undergoes calcination to produce an inverse structure.
    Type: Application
    Filed: April 3, 2017
    Publication date: May 2, 2019
    Inventors: Joanna AIZENBERG, Tanya SHIRMAN, Katherine Reece PHILLIPS, Elijah SHIRMAN, Theresa M. KAY
  • Patent number: 10265694
    Abstract: Methods for forming an interconnected network of solid material and pores, with metal residing only at the air/solid interface of the interconnected network structure are described. In certain embodiments, nanoparticle decorated sacrificial particles can be used as sacrificial templates for the formation of a porous structure having an interconnected network of solid material and interconnected network of pores. The nanoparticles reside predominantly at the air/solid interface and allow further growth and accessibility of the nanoparticles at defined positions of the interconnected structure. SEM and TEM measurements reveal the formation of 3D interconnected porous structures with nanoparticles residing predominantly at the air/solid interface of the interconnected structure.
    Type: Grant
    Filed: June 30, 2014
    Date of Patent: April 23, 2019
    Assignee: President and Fellows of Harvard College
    Inventors: Joanna Aizenberg, Tanya Shirman, Nicolas Vogel, Mathias Kolle, Michael Aizenberg
  • Publication number: 20190111657
    Abstract: The present invention relates to photonic structures and methods of controlling the optical properties and structural stability of photonic structures by using ionic species. The photonic structure is less crystalline when increasing concentrations of the ionic species are used. In certain embodiments, the ionic species is a transition metal salt. The method allows for production of single crystalline, polycrystalline, or glass-like photonic structures. The method allows for control of the optical properties and structural stability of photonic structures. The resulting photonic structures are useful in a wide range of applications, including sensors, photoactive catalysts, light emitters, and random lasing.
    Type: Application
    Filed: March 31, 2017
    Publication date: April 18, 2019
    Inventors: Joanna AIZENBERG, Tanya SHIRMAN, Elijah SHIRMAN, Katherine Reece PHILLIPS, Theresa M. KAY, Hayley C. WHELAN
  • Patent number: 10233334
    Abstract: The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces. Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of materials, referred to herein as Object A (Solid A or Liquid A). Slippery liquid-infused porous surfaces outperforms other conventional surfaces in its capability to repel various simple and complex liquids (water, hydrocarbons, crude oil and blood), maintain low-contact-angle hysteresis (<2.5°), quickly restore liquid-repellency after physical damage (within 0.1-1 s), resist ice, microorganisms and insects adhesion, and function at high pressures (up to at least 690 atm). Some exemplary application where slippery liquid-infused porous surfaces will be useful include energy-efficient fluid handling and transportation, optical sensing, medicine, and as self-cleaning, and anti-fouling materials operating in extreme environments.
    Type: Grant
    Filed: November 6, 2017
    Date of Patent: March 19, 2019
    Assignee: President and Fellows of Harvard College
    Inventors: Joanna Aizenberg, Michael Aizenberg, Sung Hoon Kang, Philseok Kim, Tak Sing Wong
  • Publication number: 20180362875
    Abstract: A method of preparing an article having a slippery surface includes providing a metal-containing surface, chemically modifying the metal-containing surface to roughen the metal-containing surface, and disposing a lubricating layer on the roughened metal-containing surface, wherein the lubricating layer is substantially stabilized on the roughened metal-containing surface.
    Type: Application
    Filed: July 2, 2018
    Publication date: December 20, 2018
    Inventors: Joanna AIZENBERG, Michael AIZENBERG, Philseok KIM
  • Patent number: 10146007
    Abstract: The rolled photonic fibers presents two codependent, technologically exploitable features for light and color manipulation: regularity on the nanoscale that is superposed with microscale cylindrical symmetry, resulting in wavelength selective scattering of light in a wide range of directions. The bio-inspired photonic fibers combine the spectral filtering capabilities and color brilliance of a planar Bragg stack compounded with a large angular scattering range introduced by the microscale curvature, which also decreases the strong directional chromaticity variation usually associated with flat multilayer reflectors. Transparent and elastic synthetic materials equip the multilayer interference fibers with high reflectance that is dynamically tuned by longitudinal mechanical strain. A two-fold elongation of the elastic fibers results in a shift of reflection peak center wavelength of over 200 nm.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: December 4, 2018
    Assignees: President and Fellows of Harvard College, University of Exeter
    Inventors: Joanna Aizenberg, Mathias Kolle, Peter Vukusic, Robert D. Howe
  • Publication number: 20180327608
    Abstract: The present disclosure describes a strategy to create self-healing, slippery self-lubricating polymers. Lubricating liquids with affinities to polymers can be utilized to get absorbed within the polymer and form a lubricant layer (of the lubricating liquid) on the polymer. The lubricant layer can repel a wide range of materials, including simple and complex fluids (water, hydrocarbons, crude oil and bodily fluids), restore liquid-repellency after physical damage, and resist ice, microorganisms and insects adhesion. Some exemplary applications where self-lubricating polymers will be useful include energy-efficient, friction-reduction fluid handling and transportation, medical devices, anti-icing, optical sensing, and as self-cleaning, and anti-fouling materials operating in extreme environments.
    Type: Application
    Filed: May 7, 2018
    Publication date: November 15, 2018
    Inventors: Joanna AIZENBERG, Michael AIZENBERG, Jiaxi CUI, Stuart DUNN, Benjamin HATTON, Caitlin HOWELL, Philseok KIM, Tak Sing WONG, Xi YAO
  • Publication number: 20180298203
    Abstract: A self-healing, scratch resistant slippery surface that is manufactured by wicking a chemically-inert, high-density liquid coating over a roughened solid surface featuring micro and nanoscale topographies is described. Such a slippery surface shows anti-wetting properties, as well as exhibits significant reduction of adhesion of a broad range of biological materials, including particles in suspension or solution. Specifically, the slippery surfaces can be applied to medical devices and equipment to effectively repel biological materials such as blood, and prevent, reduce, or delay coagulation and surface-mediated clot formation. Moreover, the slippery surfaces can be used to prevent fouling by microorganisms such as bacteria.
    Type: Application
    Filed: April 3, 2018
    Publication date: October 18, 2018
    Inventors: Joanna AIZENBERG, Benjamin HATTON, Donald INGBER, Michael SUPER, Tak Sing WONG
  • Publication number: 20180239070
    Abstract: A method of making a multi-layered film includes depositing thin film layers onto a first side of a double-sided transparent substrate. The thin film layers are transparent, and two adjacent layers of said plurality of thin film layers have different refractive indices. One or more absorbers are deposited at an interface formed between two of the thin film layers that are adjacent to one another, or formed by the first side of the substrate and one of the thin film layers. The absorbers absorb selected wavelengths of incident light and reflect part of the incident light after inducing a phase shift. The location of the interface is selected to provide desired wavelengths of absorbed and reflected light. The multi-layered film has a first appearance when viewed from the first side of the substrate and a second appearance when viewed from the second side of the substrate.
    Type: Application
    Filed: September 6, 2016
    Publication date: August 23, 2018
    Applicant: President and Fellows of Harvard College
    Inventors: Grant ENGLAND, Calvin RUSSELL, Theresa KAY, Elijah SHIRMAN, Ian BURGESS, Nicolas VOGEL, Joanna AIZENBERG
  • Publication number: 20180187022
    Abstract: The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces. Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of materials, referred to herein as Object A (Solid A or Liquid A). Slippery liquid-infused porous surfaces outperforms other conventional surfaces in its capability to repel various simple and complex liquids (water, hydrocarbons, crude oil and blood), maintain low-contact-angle hysteresis (<2.5°), quickly restore liquid-repellency after physical damage (within 0.1-1 s), resist ice, microorganisms and insects adhesion, and function at high pressures (up to at least 690 atm). Some exemplary application where slippery liquid-infused porous surfaces will be useful include energy-efficient fluid handling and transportation, optical sensing, medicine, and as self-cleaning, and anti-fouling materials operating in extreme environments.
    Type: Application
    Filed: January 25, 2018
    Publication date: July 5, 2018
    Inventors: Joanna AIZENBERG, Michael AIZENBERG, Sung Hoon KANG, Philseok KIM, Tak Sing WONG
  • Patent number: 10011800
    Abstract: A method of preparing an article having a slippery surface includes providing a metal-containing surface, chemically modifying the metal-containing surface to roughen the metal-containing surface, and disposing a lubricating layer on the roughened metal-containing surface, wherein the lubricating layer is substantially stabilized on the roughened metal-containing surface.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: July 3, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Joanna Aizenberg, Michael Aizenberg, Philseok Kim
  • Publication number: 20180127594
    Abstract: The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces. Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of materials, referred to herein as Object A (Solid A or Liquid A). Slippery liquid-infused porous surfaces outperforms other conventional surfaces in its capability to repel various simple and complex liquids (water, hydrocarbons, crude oil and blood), maintain low-contact-angle hysteresis (<2.5°), quickly restore liquid-repellency after physical damage (within 0.1-1 s), resist ice, microorganisms and insects adhesion, and function at high pressures (up to at least 690 atm). Some exemplary application where slippery liquid-infused porous surfaces will be useful include energy-efficient fluid handling and transportation, optical sensing, medicine, and as self-cleaning, and anti-fouling materials operating in extreme environments.
    Type: Application
    Filed: November 6, 2017
    Publication date: May 10, 2018
    Inventors: Joanna AIZENBERG, Michael AIZENBERG, Sung Hoon KANG, Philseok KIM, Tak Sing WONG
  • Patent number: 9963597
    Abstract: The present disclosure describes a strategy to create self-healing, slippery self-lubricating polymers. Lubricating liquids with affinities to polymers can be utilized to get absorbed within the polymer and form a lubricant layer (of the lubricating liquid) on the polymer. The lubricant layer can repel a wide range of materials, including simple and complex fluids (water, hydrocarbons, crude oil and bodily fluids), restore liquid-repellency after physical damage, and resist ice, microorganisms and insects adhesion. Some exemplary applications where self-lubricating polymers will be useful include energy-efficient, friction-reduction fluid handling and transportation, medical devices, anti-icing, optical sensing, and as self-cleaning, and anti-fouling materials operating in extreme environments.
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: May 8, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Joanna Aizenberg, Michael Aizenberg, Jiaxi Cui, Stuart Dunn, Benjamin Hatton, Caitlin Howell, Philseok Kim, Tak Sing Wong, Xi Yao
  • Patent number: 9937743
    Abstract: A document and an Anti-counterfeiting method for use in such documents are described. Said document and Anti-counterfeiting method include introducing a plurality of raised nanoscopic to microscopic structures, here referred to as reconfigurable structures, formed over a polymer substrate to induce optical changes, such as structural color and/or optical fuzziness. Dynamic changes using liquids provide the anti-counterfeiting measures.
    Type: Grant
    Filed: May 31, 2013
    Date of Patent: April 10, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Joanna Aizenberg, Tak Sing Wong, Sung Hoon Kang, Ximin He
  • Patent number: 9932482
    Abstract: The present disclosure describes a strategy to create self-healing, slippery liquid-infused porous surfaces (SLIPS). Roughened (e.g., porous) surfaces can be utilized to lock in place a lubricating fluid, referred to herein as Liquid B to repel a wide range of materials, referred to herein as Object A (Solid A or Liquid A). SLIPS outperforms other conventional surfaces in its capability to repel various simple and complex liquids (water, hydrocarbons, crude oil and blood), maintain low-contact-angle hysteresis (<2.5°), quickly restore liquid-repellency after physical damage (within 0.1-1 s), resist ice, microorganisms and insects adhesion, and function at high pressure (up to at least 690 atm). Some exemplary application where SLIPS will be useful include energy-efficient fluid handling and transportation, optical sensing, medicine, and as self-cleaning, and anti-fouling materials operating in extreme environments.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: April 3, 2018
    Assignee: President and Fellows of Harvard College
    Inventors: Joanna Aizenberg, Michael Aizenberg, Sung Hoon Kang, Philseok Kim, Tak Sing Wong