Patents by Inventor Joanna Floros

Joanna Floros has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7041638
    Abstract: A means and method for treating pulmonary fibrosis and vaginitis in animals is described. The compositions include surfactant lipids in a pharmaceutically acceptable carrier. Surfactant lipids have been found to suppress the synergistic effect of bleomycin and SP-A in enhancing proinflammatory cytokine production. Surfactant lipids are also effective in the prevention and treatment of pulmonary fibrosis resulting from exposure to inflammatory agents affecting cytokine production. Furthermore, surfactant lipids are effective in treating attenuating the effect of proinflammatory cytokine production in vaginitis.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: May 9, 2006
    Assignee: The Penn State Research Foundation
    Inventors: Joanna Floros, David S. Phelps, Colin MacNeill, Todd M. Umstead, Zhenwu Lin, Judith Weisz
  • Patent number: 6998384
    Abstract: A means and method for treating pulmonary fibrosis in animals is described. The compositions include surfactant lipids in a pharmaceutically acceptable carrier. Surfactant lipids have been found to suppress the synergistic effect of bleomycin and SP-A in enhancing proinflammatory cytokine production. Surfactant lipids are also effective in the prevention and treatment of pulmonary fibrosis resulting from exposure to inflammatory agents affecting cytokine production.
    Type: Grant
    Filed: December 12, 2002
    Date of Patent: February 14, 2006
    Assignee: The Penn State Research Foundation
    Inventors: Joanna Floros, David S. Phelps, Hamid A. Al-Mondhiry, Weixiong Huang, Guirong Wang
  • Publication number: 20030225034
    Abstract: A means and method for treating pulmonary fibrosis and vaginitis in animals is described. The compositions include surfactant lipids in a pharmaceutically acceptable carrier. Surfactant lipids have been found to suppress the synergistic effect of bleomycin and SP-A in enhancing proinflammatory cytokine production. Surfactant lipids are also effective in the prevention and treatment of pulmonary fibrosis resulting from exposure to inflammatory agents affecting cytokine production. Furthermore, surfactant lipids are effective in treating attenuating the effect of proinflammatory cytokine production in vaginitis.
    Type: Application
    Filed: May 2, 2003
    Publication date: December 4, 2003
    Applicant: The Penn State Research Foundation
    Inventors: Joanna Floros, David S. Phelps, Colin MacNeill, Todd M. Umstead, Zhenwu Lin, Judith Weisz
  • Publication number: 20030144248
    Abstract: A means and method for treating pulmonary fibrosis in animals is described. The compositions include surfactant lipids in a pharmaceutically acceptable carrier. Surfactant lipids have been found to suppress the synergistic effect of bleomycin and SP-A in enhancing proinflammatory cytokine production. Surfactant lipids are also effective in the prevention and treatment of pulmonary fibrosis resulting from exposure to inflammatory agents affecting cytokine production.
    Type: Application
    Filed: December 12, 2002
    Publication date: July 31, 2003
    Inventors: Joanna Floros, David S. Phelps, Hamid A. Al-Mondhiry, Weixiong Huang, Guirong Wang
  • Patent number: 5055553
    Abstract: This invention relates to novel proteins useful for enhancing pulmonary surfactant activity, methods and materials for obtaining said proteins and compositions containing one or more of the proteins.
    Type: Grant
    Filed: April 9, 1990
    Date of Patent: October 8, 1991
    Assignees: Genetics Institute Inc., The Brigham & Womens Hospital, Inc.
    Inventors: Kenneth A. Jacobs, D. Randall Steinbrink, Joanna Floros, David S. Phelps, H. William Taeusch
  • Patent number: 4882422
    Abstract: This invention relates to novel proteins useful for enhancing pulmonary surfactant activity, methods for obtaining said proteins and compositions containing one or more of the proteins. The proteins of this invention include the following:1. A protein characterized by a molecular weight of about 35 kd and by being encoded for by the DNA sequence depicted in Table 1.2. A protein characterized by a molecular weight of about 35 kd and by being encoded for by the DNA sequence depicted in Table 2.3. A protein encoded for by a portion of the DNA sequence depicted in Table 6 and characterized by a molecular weight of about 5.5-9 kd; and4. A protein characterized by a molecular weight of about 5.5-9 kd and an amino acid composition as set forth in Table 4.
    Type: Grant
    Filed: September 24, 1987
    Date of Patent: November 21, 1989
    Assignee: Genetics Institute, Inc.
    Inventors: H. William Taeusch, Kenneth A. Jacobs, D. Randall Steinbrink, Joanna Floros, David S. Phelps, Edward F. Fritsch