Patents by Inventor Joanne Barnes Weidhaas

Joanne Barnes Weidhaas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • REGULATION OF ONCOGENES BY MICRORNAS
    Publication number: 20110054006
    Abstract: Naturally occurring miRNAs that regulate human oncogenes and methods of use thereof are described. Suitable nucleic acids for use in the methods and compositions described herein include, but are not limited to, pri-miRNA, pre-miRNA, mature miRNA or fragments of variants thereof that retain the biological activity of the mature miRNA and DNA encoding a pri-miRNA, pre-miRNA, mature miRNA, fragments or variants thereof, or regulatory elements of the miRNA. The compositions are administered to a subject prior to administration of a cytotoxic therapy in an amount effective to sensitize cells or tissues to be treated to the effects of the cytotoxic therapy.
    Type: Application
    Filed: April 26, 2010
    Publication date: March 3, 2011
    Applicant: Yale University
    Inventors: Frank J. Slack, Steven M. Johnson, Helge Grosshans, Joanne Barnes Weidhaas
  • Regulation of oncogenes by microRNAs
    Patent number: 7741306
    Abstract: Naturally occurring miRNAs that regulate human oncogenes and methods of use thereof are described. Suitable nucleic acids for use in the methods and compositions described herein include, but are not limited to, pri-miRNA, pre-miRNA, mature miRNA ,or fragments of variants thereof that retain the biological activity of the mature miRNA and DNA encoding a pri-miRNA, pre-miRNA, mature miRNA, fragments or variants thereof, or regulatory elements of the miRNA. The compositions are administered to a subject prior to administration of a cytotoxic therapy in an amount effective to sensitize cells or tissues to be treated to the effects of the cytotoxic therapy.
    Type: Grant
    Filed: October 22, 2007
    Date of Patent: June 22, 2010
    Assignee: Yale University
    Inventors: Frank J. Slack, Steven M. Johnson, Helge Grosshans, Joanne Barnes Weidhaas