Patents by Inventor JoAnne Hansen Kerschner

JoAnne Hansen Kerschner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Whole blood sample preparation for polymerase chain reaction using ammonium chloride and a carboxylic acid or metal carboxylate for selective red blood cell lysis
    Patent number: 5702884
    Abstract: Leucocytes can be quickly and selectively separated from erythrocytes by subjecting a whole blood sample to a series of steps including lysing the erythrocytes and washing the remaining leucocytes with a solution containing ammonium chloride and a carboxylic acid or a metal carboxylate. The resulting white blood cells can be readily lysed and subjected to polymerase chain reaction to amplify and detect a target nucleic acid. The test kit useful in practicing the amplification method includes a labeled primer, a PCR reagent and a reagent mixture containing ammonium chloride and a carboxylic acid or a metal carboxylate for sample preparation.
    Type: Grant
    Filed: March 12, 1996
    Date of Patent: December 30, 1997
    Assignee: Johnson & Johnson Clinical Diagnostics, Inc.
    Inventors: Tobias E. Ekeze, JoAnne Hansen Kerschner