Patents by Inventor Joanne I. Adamkewicz

Joanne I. Adamkewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIBODIES TO MATRIX METALLOPROTEINASE 9
    Publication number: 20180002446
    Abstract: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), such as where the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
    Type: Application
    Filed: July 7, 2017
    Publication date: January 4, 2018
    Inventors: Joanne I. ADAMKEWICZ, Victoria SMITH, Zung THAI, Michael J. HAWKINS
  • THERAPEUTIC AND DIAGNOSTIC METHODS RELATED TO LYSYL OXIDASE-LIKE 2 (LOXL2)
    Publication number: 20170327595
    Abstract: Provided are therapeutic, diagnostic, and prognostic methods for disease, including diseases associated with fibrosis and cancer using agents that bind to, inhibit, and/or detect lysyl oxidase-like 2 (LOXL2), and agents, compositions, kits, assay systems, and devices for use with such methods.
    Type: Application
    Filed: January 26, 2017
    Publication date: November 16, 2017
    Inventors: Jeffrey D. Bornstein, Joanne I. Adamkewicz, Victoria Smith, Susan K. Lyman, Jason Chien, Xiaoming Li, Lixin Shao
  • LYSYL OXIDASE-LIKE 2 ASSAY AND METHODS OF USE THEREOF
    Publication number: 20170269085
    Abstract: The present disclosure provides an assay to detect and/or quantify circulating lysyl oxidase-like 2 (LOXL2) polypeptides in an individual. The assay is useful in diagnostic and prognostic applications, which are also provided.
    Type: Application
    Filed: December 1, 2016
    Publication date: September 21, 2017
    Inventors: Victoria Smith, Joanne I. Adamkewicz, Susan K. Lyman, Jason Chien, Xiaoming Li, Lixin Shao, Jeffrey D. Bornstein
  • Methods of treating rheumatoid arthritis using antibodies to matrix metalloproteinase 9
    Patent number: 9732156
    Abstract: The present disclosure provides compositions and methods of use involving binding proteins, e.g., antibodies and antigen-binding fragments thereof, that bind to the matrix metalloproteinase-9 (MMP9) protein (MMP9 is also known as gelatinase-B), such as where the binding proteins comprise an immunoglobulin (Ig) heavy chain (or functional fragment thereof) and an Ig light chain (or functional fragment thereof).
    Type: Grant
    Filed: February 28, 2013
    Date of Patent: August 15, 2017
    Assignee: Gilead Biologics, Inc.
    Inventors: Joanne I. Adamkewicz, Victoria Smith, Zung Thai, Michael J. Hawkins
  • LYSYL OXIDASE-LIKE 2 ASSAY AND METHODS OF USE THEREOF
    Publication number: 20140206017
    Abstract: The present disclosure provides an assay to detect and/or quantify circulating lysyl oxidase-like 2 (LOXL2) poly-peptides in an individual. The assay is useful in diagnostic and prognostic applications, which are also provided.
    Type: Application
    Filed: June 1, 2012
    Publication date: July 24, 2014
    Inventors: Victoria Smith, Joanne I. Adamkewicz, Susan K. Lyman, Jason Chien, Xiaoming Li, Lixin Shao, Jeffrey D. Bornstein
  • THERAPEUTIC AND DIAGNOSTIC METHODS RELATED TO LYSYL OXIDASE-LIKE 2 (LOXL2)
    Publication number: 20140120102
    Abstract: Provided are therapeutic, diagnostic, and prognostic methods for disease, including diseases associated with fibrosis and cancer using agents that bind to, inhibit, and/or detect lysyl oxidase-like 2 (LOXL2), and agents, compositions, kits, assay systems, and devices for use with such methods.
    Type: Application
    Filed: October 30, 2013
    Publication date: May 1, 2014
    Applicant: Gilead Sciences, Inc.
    Inventors: Jeffrey D. BORNSTEIN, Joanne I. ADAMKEWICZ, Victoria SMITH, Susan K. LYMAN, Jason CHIEN, Xiaoming LI, Lixin SHAO
  • ANTI-DDR1 ANTIBODIES
    Publication number: 20140086913
    Abstract: Provided are antibodies, including functional antibody fragments, that specifically bind to discoidin domain receptors (DDRs), and in particular to DDR1 proteins, as well as uses and method of using such antibodies, including in the detection, diagnosis and treatment of diseases and conditions associated with DDR1.
    Type: Application
    Filed: September 25, 2013
    Publication date: March 27, 2014
    Applicant: GILEAD SCIENCES, INC.
    Inventors: Victoria SMITH, Scott Alan MCCAULEY, Maria VAYSBERG, Joanne I. ADAMKEWICZ
  • LYSYL OXIDASE-LIKE 2 ASSAY AND METHODS OF USE THEREOF
    Publication number: 20120309020
    Abstract: The present disclosure provides an assay to detect and/or quantify circulating lysyl oxidase-like 2 (LOXL2) polypeptides in an individual. The assay is useful in diagnostic and prognostic applications, which are also provided.
    Type: Application
    Filed: June 1, 2012
    Publication date: December 6, 2012
    Applicant: Gilead Biologics, Inc.
    Inventors: Victoria Smith, Joanne I. Adamkewicz, Susan K. Lyman, Jason Chien, Xiaoming Li, Lixin Shao, Jeffrey D. Bornstein
  • PSMCs As Modifiers of the RB Pathway and Methods of Use
    Publication number: 20120107827
    Abstract: Human PSMC genes are identified as modulators of the RB pathway, and thus are therapeutic targets for disorders associated with defective RB function. Methods for identifying modulators of RB, comprising screening for agents that modulate the activity of PSMC are provided.
    Type: Application
    Filed: October 12, 2011
    Publication date: May 3, 2012
    Applicant: EXELIXIS, INC.
    Inventors: ALBERT K. TAI, CHUNYAN SONG, MICHAEL MARTIN OLLMANN, LUCILE A. GILLETT, JOANNE I. ADAMKEWICZ, KIM LICKTEIG
  • Psmcs as Modifiers of the Rb Pathway and Methods of Use
    Publication number: 20090013420
    Abstract: Human PSMC genes are identified as modulators of the RB pathway, and thus are therapeutic targets for disorders associated with defective RB function. Methods for identifying modulators of RB, comprising screening for agents that modulate the activity of PSMC are provided.
    Type: Application
    Filed: August 6, 2003
    Publication date: January 8, 2009
    Inventors: Albert K. Tai, Chunyan Song, Michael Martin Ollmann, Lucile A. Gillett, Joanne I. Adamkewicz, Kim Lickteig
  • Mbms as Modifiers of Branching Morphogenesis and Methods of Use
    Publication number: 20080213247
    Abstract: Human MBM genes are identified as modulators of branching morphogenesis, and thus are therapeutic targets for disorders associated with defective branching morphogenesis function. Methods for identifying modulators of branching morphogenesis, comprising screening for agents that modulate the activity of MBM are provided.
    Type: Application
    Filed: October 22, 2003
    Publication date: September 4, 2008
    Inventors: Gregory D. Plowman, Felix D. Karim, Candace Swimmer, Hinrich Alexander Habeck, Thomas I. Koblizek, Stefan Schulte-Merker, Ulrike Langheinrich, Gordon Mark Stott, Torsten Trowe, Andreas Michael Vogel, Joerg Heinrich Odenthal, Jochen Konrad Scheel, Torsten Tilmann Will, Yisheng Jin, Lynn Margaret Bjerke, Bing Hai, Joanne I. Adamkewicz, Kim Licketeig, R. Glenn R. Hammonds, Craig D. Amundsen, Haiguang Zhang, Monique Nicoll