Patents by Inventor Joanne Kurtzberg

Joanne Kurtzberg has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11278575
    Abstract: The present disclosure provides compositions and methods for treating demyelinating conditions. More particularly, the present disclosure relates to compositions including DUOC-01 cell product and an anti-inflammatory agent; methods for preparing such compositions; and methods of using such compositions in combination or in conjunction with each other for treatment of treating demyelinating conditions.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: March 22, 2022
    Assignee: Duke University
    Inventors: Joanne Kurtzberg, Andrew E. Balber, Arjun Saha, Pamela Noldner, Paula Scotland
  • Publication number: 20210361716
    Abstract: The present invention relates to methods of treating cerebral palsy and hypoxic-ischemic encephalopathy using cord blood tissue-derived mesenchymal stromal cells.
    Type: Application
    Filed: April 4, 2019
    Publication date: November 25, 2021
    Applicant: DUKE UNIVERSITY
    Inventors: Joanne Kurtzberg, Jessica Sun, Allen Song, Charles Michael Cotten
  • Publication number: 20210275583
    Abstract: The present disclosure provides compositions and methods for treating demyelinating conditions. More particularly, the present disclosure relates to compositions comprising a DUOC-01 cell product; methods for preparing such compositions; and methods of using such compositions for treating demyelinating conditions.
    Type: Application
    Filed: May 24, 2021
    Publication date: September 9, 2021
    Applicant: Duke University
    Inventors: Joanne Kurtzberg, Anthony Fillano, Arjun Saha, Andrew E. Balber, Ana Valverde
  • Publication number: 20210244772
    Abstract: The present disclosure provides methods for the treatment of autism spectrum disorders. More particularly, the present disclosure relates to methods of using cord blood for the treatment of autism spectrum disorders.
    Type: Application
    Filed: February 8, 2021
    Publication date: August 12, 2021
    Applicant: DUKE UNIVERSITY
    Inventors: Joanne Kurtzberg, Geraldine Dawson, Jesse Troy, Jessica Sun
  • Publication number: 20210128631
    Abstract: The present disclosure provides methods of treating Autism Spectrum Disorder. More particularly, the present disclosure relates to methods of using cord blood tissue-derived mesenchymal stromal cells to treat Autism Spectrum Disorder.
    Type: Application
    Filed: April 4, 2019
    Publication date: May 6, 2021
    Applicant: DUKE UNIVERSITY
    Inventors: Joanne Kurtzberg, Geraldine Dawson, Jessica Sun
  • Patent number: 10912801
    Abstract: The present disclosure provides methods for the treatment of autism spectrum disorders. More particularly, the present disclosure relates to methods of using cord blood for the treatment of autism spectrum disorders.
    Type: Grant
    Filed: March 13, 2018
    Date of Patent: February 9, 2021
    Assignee: DUKE UNIVERSITY
    Inventors: Joanne Kurtzberg, Geraldine Dawson, Jesse Troy, Jessica Sun
  • Publication number: 20200316039
    Abstract: The present disclosure relates to compositions and methods for enhanced engraftment of hematopoietic cells into the brain, and to therapeutic methods of treating central nervous system (CNS) diseases and disorders in subjects where replacing CNS pot macrophages (including microglia) and other tissue-resident macrophages with donor cells would be beneficial. In particular, the present disclosure relates to the use of a microglia depleting agent to enhance engraftment of hematopoietic-derived macrophages in the brain of a subject undergoing hematopoietic cell transplantation, to treat a subject suffering from a leukodystrophy and undergoing hematopoietic cell transplantation, to treat a subject suffering from a disease mediated by microglial dysfunction and undergoing hematopoietic cell transplantation, and to related methods. The present disclosure also relates to detection within cell populations of beMc? and microglia signatures.
    Type: Application
    Filed: December 15, 2018
    Publication date: October 8, 2020
    Inventors: Anthony Filiano, Joanne Kurtzberg, Jonathan Kipnis
  • Publication number: 20200069741
    Abstract: The present disclosure provides methods for the treatment of autism spectrum disorders. More particularly, the present disclosure relates to methods of using cord blood for the treatment of autism spectrum disorders.
    Type: Application
    Filed: March 13, 2018
    Publication date: March 5, 2020
    Inventors: Joanne Kurtzberg, Geraldine Dawson, Jesse Troy, Jessica Sun
  • Publication number: 20200038456
    Abstract: The present disclosure provides compositions and methods for treating demyelinating conditions. More particularly, the present disclosure relates to compositions including DUOC-01 cell product and an anti-inflammatory agent; methods for preparing such compositions; and methods of using such compositions in combination or in conjunction with each other for treatment of treating demyelinating conditions.
    Type: Application
    Filed: July 12, 2019
    Publication date: February 6, 2020
    Inventors: Joanne Kurtzberg, Andrew E. Balber, Arjun Saha, Pamela Noldner, Paula Scotland
  • Publication number: 20200016213
    Abstract: The present disclosure relates to methods of treating cerebral palsy. More particularly, the present disclosure relates to methods of using a high dose of allogeneic umbilical cord blood to treat cerebral palsy.
    Type: Application
    Filed: July 12, 2019
    Publication date: January 16, 2020
    Inventors: Joanne Kurtzberg, Jessica Sun
  • Publication number: 20190350985
    Abstract: The present disclosure relates to methods of treating cerebral palsy and hypoxic-ischemic brain injury. More particularly, the present disclosure relates to methods of using cord blood or components thereof to treat cerebral palsy and hypoxic-ischemic brain injury. The present disclosure also relates to methods of assessing neuroprotective activity of a neuroprotective agent.
    Type: Application
    Filed: January 12, 2018
    Publication date: November 21, 2019
    Inventors: Joanne Kurtzberg, Jessica Sun, Ana Valverde Vidal, Jesse Troy, C. Michael Cotten, Andrew Balber, Daniel Laskowitz, Arjun Saha
  • Publication number: 20190343882
    Abstract: The present disclosure provides compositions and methods for the treatment of demyelinating conditions. More particularly, the present disclosure relates to compositions including DUOC-01 cell product, derived from banked human umbilical cord blood (CB) mononuclear cells; methods for preparing such compositions; and methods of using such compositions for treatment of demyelinating conditions.
    Type: Application
    Filed: January 12, 2018
    Publication date: November 14, 2019
    Inventors: Joanne Kurtzberg, Andrew E. Balber, Arjun Saha, Pamela Noldner, Paula Scotland
  • Publication number: 20100129329
    Abstract: The present invention relates to methods repairing, regenerating, and reconstituting tissues by transplanting at least two stem cell populations, wherein the first and the second population of stem cells are introduced into a subject separated by a time interval of about 2 to about 24 hours. The first population comprises stem cells derived from umbilical cord. The second population comprises ALDHbr cells. These ALDHbr cells can be administered to a patient immediately after isolation or can be primed in culture using a combination of cytokines for about 2 to about 7 days prior to transplantation. The methods of the invention are useful in accelerating time to neutrophil and/or platelet engraftment and immune reconstitution following myeloablative therapy.
    Type: Application
    Filed: November 8, 2007
    Publication date: May 27, 2010
    Applicants: ALDAGEN, INC., DUKE UNIVERSITY
    Inventors: N. Rebecca Haley, Joanne Kurtzberg