Abstract: An endovascular graft of the present invention embodies a graft system utilizing the textile fabric of the prosthesis for drug storage and delivery. These drug-eluting devices involve treating the textile fabric with therapeutic agents to provide a method of delivery to both the outer surface of the graft and the inner surface of the graft. An endovascular graft system having a fuzz texturing on the outer periphery of the graft where the texturing includes a therapeutic agent coating applied to the texturing material is also contemplated. An expandable attachment frame further includes drug storage and delivery capabilities in the cavities formed in the V-hooks and apices. Therapeutic agents can also included in the radiopaque coating or loading to serve as a reservoir for controlled drug delivery.

Abstract: A endovascular graft having sensing devices attached thereto to facilitate measurement of pertinent parameters within the vasculature into which the graft is implanted. Power sources and transmitters may be attached to the graft to facilitate transmission of measurements to a receiving device outside the patient's body. The sensing devices, may be electrically passive or integrated devices with measurement and transmission capability. The sensing devices may be attached to specific locations on the graft material or attached to the lumen, thereby providing pertinent parameters from critical points inside the vasculature, or may be dispersed over the surface of the graft material or within the lumen to provide a profile of pertinent parameters. The sensing devices may be attached to the graft material with one or two sutures using a running stitch to minimize graft bulk and may be coated with a material to inhibit or control tissue growth.