Patents by Inventor Joanne Lager

Joanne Lager has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds, Compositions and Methods of Treatment Thereof
    Publication number: 20240141436
    Abstract: The present disclosure relates to treatment of a subject who has been identified with an increased A2A expression or density of A2AR+ cells.
    Type: Application
    Filed: February 17, 2022
    Publication date: May 2, 2024
    Applicant: iTeos Belgium SA
    Inventors: Chiara Martinoli, Noemie Wald, Shouraydeep Srivastava, Joanne Lager, Sally Ross
  • METHODS AND FORMULATIONS FOR ADMINISTRATION OF THIOCARBAMATE DERIVIATIVES A2A INHIBITORS
    Publication number: 20230165863
    Abstract: The present invention relates to thiocarbamate derivatives of Formula (I) which are useful as A2A adenosine receptor (A2AR) inhibitors. Especially, the present invention relates to methods and formulations for treating and/or preventing cancers in a subject with a pharmaceutical composition comprising a thiocarbamate derivative as adenosine A2A receptor inhibitor. The pharmaceutical composition of the invention is particularly useful for oral dosing in the treatment of cancer.
    Type: Application
    Filed: April 16, 2021
    Publication date: June 1, 2023
    Inventors: Olivier De Henau, Veronique Bodo, Joanne Lager, Chiara Martinoli, Manfred Schneider
  • Phosphatidylinositol 3-kinase inhibitors for the treatment of lymphoproliferative malignancies
    Patent number: 10328069
    Abstract: Methods are provided for treating a lymphoproliferative malignancy to a patient in need of such treatment, comprising administering to the patient an effective amount of compound A as described herein.
    Type: Grant
    Filed: May 19, 2017
    Date of Patent: June 25, 2019
    Assignee: EXELIXIS, INC.
    Inventors: Arthur DeCillis, Joanne Lager
  • Phosphatidylinositol 3-Kinase Inhibitors for the Treatment of Lymphoproliferative Malignancies
    Publication number: 20170296529
    Abstract: Methods are provided for treating a lymphoproliferative malignancy to a patient in need of such treatment, comprising administering to the patient an effective amount of compound A as described herein.
    Type: Application
    Filed: May 19, 2017
    Publication date: October 19, 2017
    Inventors: Arthur DeCillis, Joanne Lager
  • METHODS FOR TREATING CANCER USING PI3K INHIBITOR AND MEK INHIBITOR
    Publication number: 20150031882
    Abstract: Methods of treating patients with cancer are provided, wherein the methods comprise administering to the patient an effective amount of a MEK inhibitor and an effective amount of a PI3K inhibitor. Compositions in which the MEK and PI3K inhibitors are combined also are described.
    Type: Application
    Filed: October 2, 2014
    Publication date: January 29, 2015
    Inventors: Karl HSU, Joanne LAGER, Janet OGDEN
  • Phosphatidylinositol 3-Kinase Inhibitors for the Treatment of Lymphoproliferative Malignancies
    Publication number: 20140303172
    Abstract: Methods are provided for treating a lymphoproliferative malignancy to a patient in need of such treatment, comprising administering to the patient an effective amount of compound A as described herein.
    Type: Application
    Filed: November 1, 2012
    Publication date: October 9, 2014
    Applicant: Exelixis, Inc.
    Inventors: Arthur DeCillis, Joanne Lager
  • Combination Therapies for Treating Hematologic Malignancies Using Pyridopyrimidinone Inhibitors of PI3K/mTOR with Bendamustine and/or Rituximab
    Publication number: 20140302012
    Abstract: The invention provides a method for treating cancers including hematologic malignancies comprising administering a compound of Formula (I): in combination with one or both of bendamustine and rituximab.
    Type: Application
    Filed: June 15, 2012
    Publication date: October 9, 2014
    Applicants: Sanofi, Exelixis, Inc.
    Inventors: Arthur DeCillis, Joanne Lager, Tal Zaks
  • Method of Treating Lymphoma Using Pyridopyrimidinone Inhibitors of PI3K/mTOR
    Publication number: 20140296265
    Abstract: The invention provides a method for treating cancers including hematologic malignancies comprising administering a compound of formula I:
    Type: Application
    Filed: April 27, 2012
    Publication date: October 2, 2014
    Applicants: Sanofi, Exelixis, Inc.
    Inventors: Arthur DeCillis, Joanne Lager, Tal Zaks