Patents by Inventor JoAnne McLaurin

JoAnne McLaurin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for treatment of disorders of protein aggregation
    Publication number: 20070197453
    Abstract: The invention relates to compositions, methods and uses comprising an epi-inositol compound that provides beneficial effects in the treatment of a disorder and/or disease including a disorder in protein folding and/or aggregation, and/or amyloid formation, deposition, accumulation, or persistence. In aspects of the invention, the epi-inositol compounds provide beneficial effects in the treatment of Alzheimer's disease, dementia, and mild cognitive impairment.
    Type: Application
    Filed: February 16, 2007
    Publication date: August 23, 2007
    Inventor: JoAnne McLaurin
  • Treatment of amyloid-related diseases
    Publication number: 20070197452
    Abstract: The invention provides compositions, methods and uses comprising a scyllo-inositol compound of the formula Ia or Ib or a compound of the formula Ia or Ib wherein one, two or three hydroxyl groups are replaced by substituents with retention of configuration, or pharmaceutically acceptable salts thereof, in a therapeutically effective amount to provide beneficial effects in the treatment of an amyloid-related disease.
    Type: Application
    Filed: February 16, 2007
    Publication date: August 23, 2007
    Inventor: JoAnne McLaurin
  • Method of preventing, treating and diagnosing disorders of protein aggregation
    Publication number: 20070078099
    Abstract: Disclosed are methods of preventing, treating, or diagnosing in a subject a disorder in protein folding or aggregation, or amyloid formation, deposition, accumulation, or persistence consisting of administering to said subject a pharmaceutically effective amount of inositol stereoisomers, enantiomers or derivatives thereof.
    Type: Application
    Filed: February 27, 2004
    Publication date: April 5, 2007
    Inventor: JoAnne McLaurin
  • Compositions and methods for treatment of disorders of protein aggregation
    Publication number: 20060189582
    Abstract: The invention provides compositions, methods and uses comprising a scyllo-inositol compound that provide beneficial effects in the treatment of a disorder and/or disease including a disorder in protein folding and/or aggregation, and/or amyloid formation, deposition, accumulation, or persistence.
    Type: Application
    Filed: November 17, 2005
    Publication date: August 24, 2006
    Inventor: JoAnne McLaurin
  • Methods of preventing, treating and diagnosing disorders of protein aggregation
    Publication number: 20040204387
    Abstract: Disclosed are methods of preventing, treating, or diagnosing in a subject a disorder in protein folding or aggregation, or amyloid formation, deposition, accumulation, or persistence consisting of administering to said subject a pharmaceutically effective amount of inositol stereoisomers, enantiomers or derivatives thereof.
    Type: Application
    Filed: February 26, 2004
    Publication date: October 14, 2004
    Inventor: JoAnne McLaurin
  • Immunological methods and compositions for the treatment of Alzheimer's disease
    Publication number: 20030232758
    Abstract: The present invention relates to immunogenic compositions and peptides comprising residues 4-10 (FRHDSGY) of the amyloid peptide Abeta42. The invention further relates to antibodies that bind to the Abeta(4-10) antigenic determinant. The invention provides methods for treating Alzheimer's disease and for reducing the amyloid load in Alzheimers patients. The invention also relates to methods for designing small molecule inhibitors of amyloid deposition.
    Type: Application
    Filed: April 10, 2003
    Publication date: December 18, 2003
    Applicant: Hospital for Sick Children and University of Toronto
    Inventors: Peter H. St. George-Hyslop, JoAnne McLaurin