Patents by Inventor Joanne S. Kamens

Joanne S. Kamens has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CXCL13 binding proteins
    Publication number: 20080227704
    Abstract: The present invention encompasses CXCL13 binding proteins. Specifically, the invention relates to antibodies that are wild-type, chimeric, CDR grafted and humanized. Preferred antibodies have high affinity for CXCL13 and CXCL13 activity in vitro and in vivo. An antibody of the invention can be a full-length antibody or an antigen-binding portion thereof. Methods of making and methods of using the antibodies of the invention are also provided. The antibodies, or antigen-binding portions, of the invention are useful for detecting mouse CXCL13 and for inhibiting mouse CXCL13 activity, e.g., in a mammal suffering from a disorder in which CXCL13 activity is detrimental.
    Type: Application
    Filed: December 20, 2007
    Publication date: September 18, 2008
    Inventor: Joanne S. Kamens
  • TPL-2/COT kinase and methods of use
    Publication number: 20030219427
    Abstract: It is shown that TPL-2 is responsible for phosphorylation of p105 and its resultant proteolysis, which leads to p50 Rel translocation to the nucleus. Accordingly, the invention provides TPL-2 as a specific regulator of the activation of NF&kgr;B, and thus as a modulator of inflammatory responses in which p1O5 is involved, and as a target for the development of compounds capable of influencing NF&kgr;B activation.
    Type: Application
    Filed: February 26, 2003
    Publication date: November 27, 2003
    Inventors: Hamish J. Allen, Richard W. Dixon, Joanne S. Kamens, Dineli Wickramasinghe, Yajun Xu, Nancy Bump, Andres Salmeron, Monica P. Belich, Leland H. Johnston, Steven C. Ley, Steven J. Gamblin, Stephen J. Smerdon, Soeren Beinke, Juergen Deka