Patents by Inventor Joanne Van Ryn

Joanne Van Ryn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dabigatran antidotes
    Patent number: 9499633
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Grant
    Filed: October 23, 2014
    Date of Patent: November 22, 2016
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Tobias Litzenburger, Herbert Nar, Felix Schiele, Daniel Seeliger, Joanne Van Ryn
  • ANTICOAGULANT ANTIDOTES
    Publication number: 20150210778
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Application
    Filed: April 13, 2015
    Publication date: July 30, 2015
    Inventors: Joanne VAN RYN, John Edward PARK, Norbert HAUEL, Ulrich KUNZ, Tobias LITZENBURGER, Keith CANADA, Sanjaya SINGH, Alisa K. WATERMAN
  • Methods of using antibodies during anticoagulant therapy of dabigatran and/or related compounds
    Patent number: 9034822
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Grant
    Filed: June 13, 2013
    Date of Patent: May 19, 2015
    Assignee: Boehringer Igelheim International GmbH
    Inventors: Joanne Van Ryn, John Edward Park, Norbert Hauel, Ulrich Kunz, Tobias Litzenburger, Keith Canada, Sanjaya Singh, Alisa Waterman
  • ANTICOAGULANT ANTIDOTES
    Publication number: 20150118225
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Application
    Filed: October 23, 2014
    Publication date: April 30, 2015
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Tobias LITZENBURGER, Herbert NAR, Felix SCHIELE, Daniel SEELIGER, Joanne VAN RYN
  • ANTICOAGULANT ANTIDOTES
    Publication number: 20140377265
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Application
    Filed: July 22, 2014
    Publication date: December 25, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne VAN RYN, Keith CANADA, Robert COPENHAVER, Norbert HAUEL, Tobias LITZENBURGER, Christopher Ronald SARKO, Sanjaya SINGH, Alisa K. WATERMAN
  • Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds and methods of use thereof
    Patent number: 8821871
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Grant
    Filed: March 28, 2012
    Date of Patent: September 2, 2014
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Joanne Van Ryn, Keith Canada, Robert Copenhaver, Norbert Hauel, Tobias Litzenburger, Christopher Ronald Sarko, Sanjaya Singh, Alisa K. Waterman
  • COMBINATION THERAPY IN TREATMENT OF ONCOLOGICAL AND FIBROTIC DISEASES
    Publication number: 20140187563
    Abstract: The invention relates to new methods for the treatment of oncological and fibrotic disease comprising the combined administration of an inhibitor of vascular endothelial growth factor receptors (VEGFRs) in conjunction with a thrombin inhibitor.
    Type: Application
    Filed: March 6, 2014
    Publication date: July 3, 2014
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Joanne VAN RYN, Frank HILBERG, Pilar GARIN-CHESA
  • COMBINATION THERAPY IN TREATMENT OF CANCER AND FIBROTIC DISEASES
    Publication number: 20140066456
    Abstract: The invention relates to new methods for the treatment of oncological and fibrotic diseases comprising the combined administration of a receptor tyrosine kinase inhibitor in conjunction with a thrombin inhibitor.
    Type: Application
    Filed: November 6, 2013
    Publication date: March 6, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne VAN RYN, Pilar GARIN-CHESA, Flavio SOLCA
  • DABIGATRAN IN TUMOR THERAPY
    Publication number: 20140051728
    Abstract: The invention relates to a new use of dabigatran etexilate of formula I optionally in the form of the pharmaceutically acceptable salts thereof, as well as new medicament formulations which may be used for this purpose.
    Type: Application
    Filed: October 28, 2013
    Publication date: February 20, 2014
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne VAN RYN, Andreas CLEMENS
  • EMERGENCY INTERVENTIONS OF ACTIVE CHARCOAL WITH DABIGATRAN ETEXILATE OVERDOSING
    Publication number: 20130302311
    Abstract: The invention relates to a method for treating an overdosing with active substance dabigatran etexilate of formula I optionally in the form of the pharmaceutically acceptable salts thereof, comprising the administration of an effective amount of charcoal.
    Type: Application
    Filed: July 22, 2013
    Publication date: November 14, 2013
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne VAN RYN, Andreas CLEMENS
  • ANTICOAGULANT ANTIDOTES
    Publication number: 20130289248
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Application
    Filed: June 13, 2013
    Publication date: October 31, 2013
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne VAN RYN, John Edward PARK, Norbert HAUEL, Ulrich KUNZ, Tobias LITZENBURGER, Keith CANADA, Sanjaya SINGH, Alisa WATERMAN
  • Anticoagulant antidotes comprising antibodies that bind dabigatran and/or related compounds
    Patent number: 8486398
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Grant
    Filed: January 20, 2011
    Date of Patent: July 16, 2013
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Joanne Van Ryn, John Edward Park, Norbert Hauel, Ulrich Kunz, Tobias Litzenburger, Keith Canada, Sanjaya Singh, Alisa Waterman
  • ANTICOAGULANT ANTIDOTES
    Publication number: 20120276123
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Application
    Filed: March 28, 2012
    Publication date: November 1, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne VAN RYN, Keith CANADA, Robert COPENHAVER, Norbert HAUEL, Tobias LITZENBURGER, Christopher Ronald SARKO, Sanjaya SINGH, Alisa K. WATERMAN
  • NEW COMBINATION THERAPY IN TREATMENT OF ONCOLOGICAL AND FIBROTIC DISEASES
    Publication number: 20120142703
    Abstract: The invention relates to new methods for the treatment of oncological and fibrotic disease comprising the combined administration of an inhibitor of vascular endothelial growth factor receptors (VEGFRs) in conjunction with a thrombin inhibitor.
    Type: Application
    Filed: May 11, 2010
    Publication date: June 7, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne Van Ryn, Frank Hilberg, Pilar Garin-Chesa
  • NEW COMBINATION THERAPY IN TREATMENT OF CANCER AND FIBROTIC DISEASES
    Publication number: 20120136004
    Abstract: The invention relates to new methods for the treatment of oncological and fibrotic diseases comprising the combined administration of a receptor tyrosine kinase inhibitor in conjunction with a thrombin inhibitor.
    Type: Application
    Filed: May 11, 2010
    Publication date: May 31, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne Van Ryn, Pilar Garin-Chesa, Flavio Solca
  • ANTICOAGULANT ANTIDOTES
    Publication number: 20120027780
    Abstract: The present invention relates to antibody molecules against anticoagulants, in particular dabigatran, and their use as antidotes of such anticoagulants.
    Type: Application
    Filed: January 20, 2011
    Publication date: February 2, 2012
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne Van Ryn, John Edward Park, Norbert Hauel, Ulrich Kunz, Tobias Litzenburger, Keith Canada, Sanjaya Singh, Alisa Waterman
  • DABIGATRAN IN TUMOUR THERAPY
    Publication number: 20110306640
    Abstract: The invention relates to the use of dabigatran etexilate of Formula (I) optionally in the form of the pharmaceutically acceptable salts thereof, as well as new medicament formulations for the treatment of tumours.
    Type: Application
    Filed: August 17, 2009
    Publication date: December 15, 2011
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Joanne Van Ryn, Andreas Clemens
  • EMERGENCY INTERVENTIONS OF ACTIVE CHARCOAL WITH DABIGATRAN ETEXILATE OVERDOSING
    Publication number: 20110206656
    Abstract: The invention relates to a method for treating an overdosing with active substance dabigatran etexilate of formula I optionally in the form of the pharmaceutically acceptable salts thereof, comprising the administration of an effective amount of charcoal.
    Type: Application
    Filed: August 24, 2010
    Publication date: August 25, 2011
    Applicant: BOEHRINGER INGELHEIM INTERNATIONAL GMBH
    Inventors: Joanne Van Ryn, Andreas Clemens
  • Composition comprising a combined thromboxane receptor antagonist and thromboxane synthase inhibitor and a COX-2 inhibitor
    Publication number: 20060217431
    Abstract: The invention relates to a pharmaceutical composition comprising a combined thromboxane receptor antagonist and thromboxane synthase inhibitor and a COX-2 inhibitor. In addition a method of treating cyclooxygenase dependent disorders, including inflammation, pain and/or rheumatic diseases, and/or neoplasia is described.
    Type: Application
    Filed: March 20, 2006
    Publication date: September 28, 2006
    Applicant: Boehringer Ingelheim International GmbH
    Inventors: Juergen Daemmgen, Joanne van Ryn, Brian Guth, Michel Pairet
  • 4-Hydroxy-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxides, process for preparing and pharmaceutical compositions thereof
    Publication number: 20040087580
    Abstract: The present invention relates to new 4-hydroxy-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide-1,1-dioxides of general formula 1
    Type: Application
    Filed: July 21, 2003
    Publication date: May 6, 2004
    Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
    Inventors: Guenter Trummlitz, Wolfhard Engel, Wolfgang Eberlein, Guenther Engelhardt, Joanne Van Ryn