Abstract: The present invention generally relates to a pharmaceutical formulation that substantially increases the bioavailability of niclosamide or a pharmaceutically acceptable salt thereof for a variety of routes of delivery for therapeutic purposes. The newly enhanced formulation also substantially expands the potential therapeutic applications of niclosamide. Pharmaceutical compositions and methods of uses thereof are within the scope of this disclosure.

Abstract: Compositions including a highly branched alpha-D-glucan or modified forms thereof and a solute compound are described herein. The compositions can provide increased water solubility and/or increased rate of dissolution for the solute compound. The compositions can also provide increased stability for the solute compound. Methods for preparing and using compositions including a solute compound and a highly branched alpha-D-glucan are also described.

Abstract: Compositions including a highly branched alpha-D-glucan or modified forms thereof and a solute compound are described herein. The compositions can provide increased water solubility and/or increased rate of dissolution for the solute compound. The compositions can also provide increased stability for the solute compound. Methods for preparing and using compositions including a solute compound and a highly branched alpha-D-glucan are also described.

Abstract: The present invention provides a transcription amplification system, comprising an effector nucleic acid molecule and a reporter molecule, which work together to produce a heterologous gene product in a cell-type, specific manner. The present invention also relates to methods for producing, detecting, imaging, and monitoring the heterologous gene product in a cell or in a subject.

Abstract: The present invention provides a transcription amplification system, comprising an effector nucleic acid molecule and a reporter molecule, which work together to produce a heterologous gene product in a cell-type, specific manner. The present invention also relates to methods for producing, detecting, imaging, and monitoring the heterologous gene product in a cell or in a subject.

Abstract: The present invention provides a support mechanism for holding a component in a component rack, a method of manufacture therefor, and a rack of components. The support mechanism, among other elements, may include a shelf configured to hold a component, the shelf having a sidewall with at least two slots therein extending from the sidewall and the shelf. The support mechanism may further included a mounting flange coupleable to the shelf, the mounting flange having at least two tabs configured to engage the at least two slots.

Abstract: For use with a power converter shelf having a rear wall, a floating power connector mount and a power converter rack incorporating the power connector mount. In one embodiment, the power connector mount includes a float housing having a recess therein configured to receive and capture a flange of a standards-based power connector between the float housing and the rear wall, the standards-based power connector enabled to float or move freely within the recess.

Abstract: The present invention provides a heat sink that, in an advantageous embodiment, includes a spine having a width with first and second opposing sides that are oriented to be abnormal to the substrate when the heat sink is mounted on the substrate. The heat sink further includes an electronic device support leg that extends generally transverse from the first side and that is configured to support a heat generating electrical component thereon. Alternative embodiments of the present invention may include a plurality of such electronic device support legs. A plurality of cooling fins are also included in the present invention, extending from the second side. Moreover, each of the plurality of cooling fins has a depth that is substantially less than the width of the heat sink, which give this unique heat sink an exceptional cooling efficiency. In particular advantageous embodiments, the depth to width ratio of the fins and spine, may range from about 1 to 5 or 1 to 10, respectively.

Abstract: For use with an electronics chassis having a chassis plug mounted to a wall thereof, a retention bracket for securing an outlet end of a line cord to the chassis plug and methods of operating and manufacturing the same. In one embodiment, the bracket includes: (1) a strap that defines a receiver for accepting and surrounding a body of the outlet end, the strap terminating in first and second locking members projecting radially from the receiver and having corresponding alignable first and second strap apertures and (2) first and second chassis anchors projecting from the strap in a direction substantially parallel to a centerline of the receiver, the outlet end engageable with the chassis plug, the first and second chassis anchors lockable with the wall via corresponding chassis apertures therein, a brace projecting from the wall and having a brace aperture aligning with the first and second strap apertures.