Patents by Inventor Joao A. C. Lima
Joao A. C. Lima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10736593Abstract: An X-ray diagnostic apparatus according to the embodiment includes an X-ray tube, an X-ray detector, image generating unit generating time-series medical images of vasoganglion in a predetermined organ of a subject, region setting unit setting a first upstream and downstream region of a stenosis location in a first blood vessel in the vasoganglion on the medical images, curve generating unit generating a stenosis upstream and downstream curve indicating a change in pixel value in the time-series based on pixel values included in the first upstream and downstream region respectively, stenosis index generating unit generating a stenosis index indicating the degree of stenosis in the first blood vessel based on the stenosis upstream and downstream curve, and display unit displaying the stenosis index.Type: GrantFiled: December 5, 2014Date of Patent: August 11, 2020Assignees: Canon Medical Systems Corporation, The Johns Hopkins UniversityInventors: Jingwu Yao, Takuya Sakaguchi, Jeff Trost, Richard T. George, Joao A. C. Lima, Omair Yousuf
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Patent number: 10368753Abstract: An embodiment in accordance with the present invention provides a system and method for determining cardiac events. The system and method include using an imaging modality to obtain a cardiac image of the subject. The image is then used to determine the subject's systolic, post-systolic, and early diastolic strain peaks. Additionally, a strain rate index (SRI) value is computed for the subject using the systolic, post-systolic, and early diastolic strain peaks. The SRI value can then be used to determine a level of risk of cardiac failure. Further, a likelihood of atrial fibrillation can also be determined. The SRI value and risk of cardiac event can then be used to create a treatment plan for the subject, if necessary.Type: GrantFiled: November 1, 2013Date of Patent: August 6, 2019Assignee: The Johns Hopkins UniversityInventors: Bharath Ambale Venkatesh, Anderson Armstrong, Joao A. C. Lima, Chia-Ying Liu, Boaz D. Rosen
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Publication number: 20150289769Abstract: An embodiment in accordance with the present invention provides a system and method for determining cardiac events. The system and method include using an imaging modality to obtain a cardiac image of the subject. The image is then used to determine the subject's systolic, post-systolic, and early diastolic strain peaks. Additionally, a strain rate index (SRI) value is computed for the subject using the systolic, post-systolic, and early diastolic strain peaks. The SRI value can then be used to determine a level of risk of cardiac failure. Further, a likelihood of atrial fibrillation can also be determined. The SRI value and risk of cardiac event can then be used to create a treatment plan for the subject, if necessary.Type: ApplicationFiled: November 1, 2013Publication date: October 15, 2015Inventors: Bharath Ambale Venkatesh, Anderson Armstrong, Joao A.C. Lima, Chia-Ying Liu, Boaz D. Rosen
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Patent number: 9072490Abstract: In one embodiment, an image processing apparatus includes a difference image generating unit and a display controlling unit. The difference image generating unit generates a difference image by calculating a difference in a second X-ray transmission image from a first X-ray transmission image, the second X-ray transmission image being an image in which a myocardial tissue of an examined subject is not opacified and the first X-ray transmission image being an image in which the myocardial tissue of the examined subject is opacified with a contrast agent that has been injected into a coronary artery. The display controlling unit exercises control so that a predetermined display unit displays the difference image that has been generated by the difference image generating unit.Type: GrantFiled: December 20, 2010Date of Patent: July 7, 2015Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins UniversityInventors: Takuya Sakaguchi, Hisato Takemoto, Joao A. C. Lima, Richard T. George, Jeff Trost
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Publication number: 20150087956Abstract: An X-ray diagnostic apparatus according to the embodiment includes an X-ray tube, an X-ray detector, image generating unit generating time-series medical images of vasoganglion in a predetermined organ of a subject, region setting unit setting a first upstream and downstream region of a stenosis location in a first blood vessel in the vasoganglion on the medical images, curve generating unit generating a stenosis upstream and downstream curve indicating a change in pixel value in the time-series based on pixel values included in the first upstream and downstream region respectively, stenosis index generating unit generating a stenosis index indicating the degree of stenosis in the first blood vessel based on the stenosis upstream and downstream curve, and display unit displaying the stenosis index.Type: ApplicationFiled: December 5, 2014Publication date: March 26, 2015Applicants: Toshiba Medical Systems Corporation, The Johns Hopkins UniversityInventors: Jingwu Yao, Takuya Sakaguchi, Jeff Trost, Richard T. George, Joao A.C. Lima, Omair Yousuf
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Patent number: 8965085Abstract: An image processing apparatus according to the present embodiment includes a correcting unit. The correcting unit identifies, based on an observation value of a residual contrast material component that is injected to a subject before a predetermined timing and remains in the subject, the residual contrast material component and a new contrast material component that is newly injected to the subject after the predetermined timing regarding a contrast material component that is included in an image, and corrects an observation value of the contrast material component included in the image.Type: GrantFiled: May 3, 2013Date of Patent: February 24, 2015Assignees: Toshiba Medical Systems Corporation, Fujita Health University, The Johns Hopkins UniversityInventors: Takuya Sakaguchi, Takashi Ichihara, Jingwu Yao, Richard T. George, Jeff Trost, Omair Khwaja Yousuf, Joao A. C. Lima
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Publication number: 20140086461Abstract: A predetermined time-based index ratio such as time-based fractional flow reserve (FFR) is determined for evaluating a level of blood circulation between at least two locations such as a proximal location and a distal location in a selected blood vessel in the region of interest. One time-based FFR is obtained by normalizing a risk artery ratio by a reference artery ratio.Type: ApplicationFiled: September 25, 2012Publication date: March 27, 2014Applicants: THE JOHNS HOPKINS UNIVERSITY, TOSHIBA MEDICAL SYSTEMS CORPORATIONInventors: Jingwu YAO, Takuya SAKAGUCHI, Jeff TROST, Richard T. GEORGE, Joao A.C. LIMA, Omair YOUSUF
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Patent number: 8615116Abstract: A computed tomography system has a support stage constructed and arranged to support a subject while under observation, an x-ray illumination system arranged proximate the support stage to illuminate the subject with x-rays, an x-ray detection system arranged proximate the support stage to detect x-rays after they pass through the subject and to provide signals based on the detected x-rays, and a data processing system in communication with the x-ray detection system to receive the signals from the x-ray detection system. The computed tomography system has a dynamic mode of operation and a scanning mode of operation. The data processing system extracts information concerning a dynamic process of the subject based on signals from both the dynamic mode and the scanning mode of operation.Type: GrantFiled: September 29, 2008Date of Patent: December 24, 2013Assignees: The Johns Hopkins University, Toshiba Medical Systems CorporationInventors: Albert Clark Lardo, Richard T. George, Joao A. C. Lima, Eduardo T. Marban, Takashi Ichihara
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Publication number: 20130243301Abstract: An image processing apparatus according to the present embodiment includes a correcting unit. The correcting unit identifies, based on an observation value of a residual contrast material component that is injected to a subject before a predetermined timing and remains in the subject, the residual contrast material component and a new contrast material component that is newly injected to the subject after the predetermined timing regarding a contrast material component that is included in an image, and corrects an observation value of the contrast material component included in the image.Type: ApplicationFiled: May 3, 2013Publication date: September 19, 2013Applicant: Toshiba Medical Systems CorporationInventors: Takuya SAKAGUCHI, Takashi ICHIHARA, Jingwu YAO, Richard T. GEORGE, Jeff TROST, Omair Khwaja YOUSUF, Joao A. C. LIMA
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Patent number: 8498462Abstract: An image processing apparatus includes a storage unit which stores volume data associated with an area including a contrast-enhanced artery as an examination target, a first calculation unit which calculates a plurality of partial atherosclerotic indexes associated with a plurality of portions of the artery on the basis of morphological information associated with the artery which is obtained from the volume data, a second calculation unit which calculates a whole atherosclerotic index associated with the entire artery including the plurality of portions on the basis of the morphological information associated with the artery, and a display unit which displays evaluation information based on the calculated whole atherosclerotic index.Type: GrantFiled: September 24, 2008Date of Patent: July 30, 2013Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins UniversityInventors: Hiroyuki Niinuma, Kakuya Kitagawa, Joao A. C. Lima, Yasuko Fujisawa, Miwa Okumura
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Patent number: 8208703Abstract: A motion function of a biological tissue is efficiently evaluated on the basis of image data collected from different medical image diagnostic apparatuses. In terms of a common analysis algorithm applied to subject's time-series image data supplied from a separate medical image diagnostic apparatus, a setting part sets a plurality of interest points on a myocardial tissue of a reference image data extracted from the image data, and a tracking process part measures a motion parameter on the basis of displacement information of the myocardial tissue at the interest points obtained by a tracking process between the reference image data and subsequent image data thereof. Meanwhile, a data creating unit creates parameter image data showing two-dimension distribution of the motion parameter or parameter time-series data showing a variation in time of the motion parameter as parameter data on the basis of the measurement result, and displays the parameter data.Type: GrantFiled: November 5, 2008Date of Patent: June 26, 2012Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins UniversityInventors: Tetsuya Kawagishi, Hiroyuki Ohuchi, Yasuhiko Abe, Thomas Helle-Valle, Joao A. C. Lima
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Publication number: 20120155737Abstract: In one embodiment, an image processing apparatus includes a difference image generating unit and a display controlling unit. The difference image generating unit generates a difference image by calculating a difference in a second X-ray transmission image from a first X-ray transmission image, the second X-ray transmission image being an image in which a myocardial tissue of an examined subject is not opacified and the first X-ray transmission image being an image in which the myocardial tissue of the examined subject is opacified with a contrast agent that has been injected into a coronary artery. The display controlling unit exercises control so that a predetermined display unit displays the difference image that has been generated by the difference image generating unit.Type: ApplicationFiled: December 20, 2010Publication date: June 21, 2012Applicants: THE JOHNS HOPKINS UNIVERSITY, TOSHIBA MEDICAL SYSTEMS CORPORATIONInventors: Takuya SAKAGUCHI, Hisato Takemoto, Joao A. C. Lima, Richard T. George, Jeff Trost
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Patent number: 8160338Abstract: An apparatus includes a transformation table acquiring unit, a blood-flow information acquisition unit and a blood-flow image generating unit. The transformation table acquiring unit obtains a transformation table for transforming unspecified information representing a concentration of a contrast medium in a myocardium into an unspecified blood flow value image based on a CT image acquired in a concentration transition period. The blood-flow information acquisition unit obtains information representing the concentration of the contrast medium based on a CT image acquired during a constant concentration period. The blood-flow image generating unit generates a blood flow value image based on the information representing the concentration of the contrast medium according to the transformation table.Type: GrantFiled: May 20, 2008Date of Patent: April 17, 2012Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins UniversityInventors: Takashi Ichihara, Richard T. George, Joao A. C. Lima, Albert C. Lardo
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Publication number: 20110110488Abstract: A computed tomography system has a support stage constructed and arranged to support a subject while under observation, an x-ray illumination system arranged proximate the support stage to illuminate the subject with x-rays, an x-ray detection system arranged proximate the support stage to detect x-rays after they pass through the subject and to provide signals based on the detected x-rays, and a data processing system in communication with the x-ray detection system to receive the signals from the x-ray detection system. The computed tomography system has a dynamic mode of operation and a scanning mode of operation. The data processing system extracts information concerning a dynamic process of the subject based on signals from both the dynamic mode and the scanning mode of operation.Type: ApplicationFiled: September 29, 2008Publication date: May 12, 2011Applicant: THE JOHNS HOPKINS UNIVERSITYInventors: Albert Clark Lardo, Richard T. George, Joao A.C. Lima, Eduardo Marban
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Patent number: 7853309Abstract: An X-ray CT apparatus comprises a blood-flow information acquisition unit, a correction value calculating unit and a blood-flow image generating unit. The blood-flow information acquisition unit obtains information of a relative blood flow rate in the myocardium of the subject based on the CT image. The correction value calculating unit obtains a correction value based on the CT image in a concentration transition period defined to be a period from immediately after start of a continuous injection of a contrast medium into the subject until the contrast medium reaching the myocardium increases and is be in a state where it can be considered that the contrast medium is saturated at a constant value. The blood-flow image generating unit generates a blood flow value image in the myocardium by correcting the information of the relative blood flow rate with the correction value.Type: GrantFiled: March 10, 2005Date of Patent: December 14, 2010Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins UniversityInventors: Takashi Ichihara, Toshihiro Rifu, Joao A. C. Lima, Richard T. George, Albert C. Lardo
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Publication number: 20100111380Abstract: A motion function of a biological tissue is efficiently evaluated on the basis of image data collected from different medical image diagnostic apparatuses. In terms of a common analysis algorithm applied to subject's time-series image data supplied from a separate medical image diagnostic apparatus, a setting part sets a plurality of interest points on a myocardial tissue of a reference image data extracted from the image data, and a tracking process part measures a motion parameter on the basis of displacement information of the myocardial tissue at the interest points obtained by a tracking process between the reference image data and subsequent image data thereof. Meanwhile, a data creating unit creates parameter image data showing two-dimension distribution of the motion parameter or parameter time-series data showing a variation in time of the motion parameter as parameter data on the basis of the measurement result, and displays the parameter data.Type: ApplicationFiled: November 5, 2008Publication date: May 6, 2010Inventors: Tetsuya Kawagishi, Hiroyuki Ohuchi, Yasuhiko Abe, Thomas Helle-Valle, Joao A. C. Lima
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Publication number: 20090268954Abstract: An image processing apparatus includes a storage unit which stores volume data associated with an area including a contrast-enhanced artery as an examination target, a first calculation unit which calculates a plurality of partial atherosclerotic indexes associated with a plurality of portions of the artery on the basis of morphological information associated with the artery which is obtained from the volume data, a second calculation unit which calculates a whole atherosclerotic index associated with the entire artery including the plurality of portions on the basis of the morphological information associated with the artery, and a display unit which displays evaluation information based on the calculated whole atherosclerotic index.Type: ApplicationFiled: September 24, 2008Publication date: October 29, 2009Inventors: Hiroyuki NIINUMA, Kakuya KITAGAWA, Joao A.C. LIMA, Yasuko FUJISAWA, Miwa OKUMURA
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Publication number: 20090129536Abstract: An apparatus includes a transformation table acquiring unit, a blood-flow information acquisition unit and a blood-flow image generating unit. The transformation table acquiring unit obtains a transformation table for transforming unspecified information representing a concentration of a contrast medium in a myocardium into an unspecified blood flow value image based on a CT image acquired in a concentration transition period. The blood-flow information acquisition unit obtains information representing the concentration of the contrast medium based on a CT image acquired during a constant concentration period. The blood-flow image generating unit generates a blood flow value image based on the information representing the concentration of the contrast medium according to the transformation table.Type: ApplicationFiled: May 20, 2008Publication date: May 21, 2009Applicants: TOSHIBA MEDICAL SYSTEMS CORPORATION, THE JOHNS HOPKINS UNIVERSITYInventors: Takashi Ichihara, Richard T. George, Joao A.C. Lima, Albert C. Lardo
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Patent number: 6408202Abstract: A method of transesophageal magnetic resonance analysis of a patient, such as an animal or human, includes providing a loopless antenna formed from a flexible coaxial cable having an extended center conductor at the distal end thereof. A distal portion of the loopless antenna is secured within a Levin-type gastric tube. The gastric tube which receives the loopless antenna is inserted in the esophagus of the patient. A tuning, matching and decoupling circuit for the loopless antenna is employed external to the patient. The tuning, matching and decoupling circuit is electrically connected to a magnetic resonance imaging scanner. The magnetic resonance imaging scanner is employed to display an image of the aorta of the patient.Type: GrantFiled: November 3, 1999Date of Patent: June 18, 2002Assignee: The Johns Hopkins UniversityInventors: Joao A. C. Lima, Kendrick A. Shunk, Ergin Atalar