Patents by Inventor Joao A. C. Lima

Joao A. C. Lima has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10736593
    Abstract: An X-ray diagnostic apparatus according to the embodiment includes an X-ray tube, an X-ray detector, image generating unit generating time-series medical images of vasoganglion in a predetermined organ of a subject, region setting unit setting a first upstream and downstream region of a stenosis location in a first blood vessel in the vasoganglion on the medical images, curve generating unit generating a stenosis upstream and downstream curve indicating a change in pixel value in the time-series based on pixel values included in the first upstream and downstream region respectively, stenosis index generating unit generating a stenosis index indicating the degree of stenosis in the first blood vessel based on the stenosis upstream and downstream curve, and display unit displaying the stenosis index.
    Type: Grant
    Filed: December 5, 2014
    Date of Patent: August 11, 2020
    Assignees: Canon Medical Systems Corporation, The Johns Hopkins University
    Inventors: Jingwu Yao, Takuya Sakaguchi, Jeff Trost, Richard T. George, Joao A. C. Lima, Omair Yousuf
  • Patent number: 10368753
    Abstract: An embodiment in accordance with the present invention provides a system and method for determining cardiac events. The system and method include using an imaging modality to obtain a cardiac image of the subject. The image is then used to determine the subject's systolic, post-systolic, and early diastolic strain peaks. Additionally, a strain rate index (SRI) value is computed for the subject using the systolic, post-systolic, and early diastolic strain peaks. The SRI value can then be used to determine a level of risk of cardiac failure. Further, a likelihood of atrial fibrillation can also be determined. The SRI value and risk of cardiac event can then be used to create a treatment plan for the subject, if necessary.
    Type: Grant
    Filed: November 1, 2013
    Date of Patent: August 6, 2019
    Assignee: The Johns Hopkins University
    Inventors: Bharath Ambale Venkatesh, Anderson Armstrong, Joao A. C. Lima, Chia-Ying Liu, Boaz D. Rosen
  • Publication number: 20150289769
    Abstract: An embodiment in accordance with the present invention provides a system and method for determining cardiac events. The system and method include using an imaging modality to obtain a cardiac image of the subject. The image is then used to determine the subject's systolic, post-systolic, and early diastolic strain peaks. Additionally, a strain rate index (SRI) value is computed for the subject using the systolic, post-systolic, and early diastolic strain peaks. The SRI value can then be used to determine a level of risk of cardiac failure. Further, a likelihood of atrial fibrillation can also be determined. The SRI value and risk of cardiac event can then be used to create a treatment plan for the subject, if necessary.
    Type: Application
    Filed: November 1, 2013
    Publication date: October 15, 2015
    Inventors: Bharath Ambale Venkatesh, Anderson Armstrong, Joao A.C. Lima, Chia-Ying Liu, Boaz D. Rosen
  • Patent number: 9072490
    Abstract: In one embodiment, an image processing apparatus includes a difference image generating unit and a display controlling unit. The difference image generating unit generates a difference image by calculating a difference in a second X-ray transmission image from a first X-ray transmission image, the second X-ray transmission image being an image in which a myocardial tissue of an examined subject is not opacified and the first X-ray transmission image being an image in which the myocardial tissue of the examined subject is opacified with a contrast agent that has been injected into a coronary artery. The display controlling unit exercises control so that a predetermined display unit displays the difference image that has been generated by the difference image generating unit.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: July 7, 2015
    Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins University
    Inventors: Takuya Sakaguchi, Hisato Takemoto, Joao A. C. Lima, Richard T. George, Jeff Trost
  • Publication number: 20150087956
    Abstract: An X-ray diagnostic apparatus according to the embodiment includes an X-ray tube, an X-ray detector, image generating unit generating time-series medical images of vasoganglion in a predetermined organ of a subject, region setting unit setting a first upstream and downstream region of a stenosis location in a first blood vessel in the vasoganglion on the medical images, curve generating unit generating a stenosis upstream and downstream curve indicating a change in pixel value in the time-series based on pixel values included in the first upstream and downstream region respectively, stenosis index generating unit generating a stenosis index indicating the degree of stenosis in the first blood vessel based on the stenosis upstream and downstream curve, and display unit displaying the stenosis index.
    Type: Application
    Filed: December 5, 2014
    Publication date: March 26, 2015
    Applicants: Toshiba Medical Systems Corporation, The Johns Hopkins University
    Inventors: Jingwu Yao, Takuya Sakaguchi, Jeff Trost, Richard T. George, Joao A.C. Lima, Omair Yousuf
  • Patent number: 8965085
    Abstract: An image processing apparatus according to the present embodiment includes a correcting unit. The correcting unit identifies, based on an observation value of a residual contrast material component that is injected to a subject before a predetermined timing and remains in the subject, the residual contrast material component and a new contrast material component that is newly injected to the subject after the predetermined timing regarding a contrast material component that is included in an image, and corrects an observation value of the contrast material component included in the image.
    Type: Grant
    Filed: May 3, 2013
    Date of Patent: February 24, 2015
    Assignees: Toshiba Medical Systems Corporation, Fujita Health University, The Johns Hopkins University
    Inventors: Takuya Sakaguchi, Takashi Ichihara, Jingwu Yao, Richard T. George, Jeff Trost, Omair Khwaja Yousuf, Joao A. C. Lima
  • Publication number: 20140086461
    Abstract: A predetermined time-based index ratio such as time-based fractional flow reserve (FFR) is determined for evaluating a level of blood circulation between at least two locations such as a proximal location and a distal location in a selected blood vessel in the region of interest. One time-based FFR is obtained by normalizing a risk artery ratio by a reference artery ratio.
    Type: Application
    Filed: September 25, 2012
    Publication date: March 27, 2014
    Applicants: THE JOHNS HOPKINS UNIVERSITY, TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventors: Jingwu YAO, Takuya SAKAGUCHI, Jeff TROST, Richard T. GEORGE, Joao A.C. LIMA, Omair YOUSUF
  • Patent number: 8615116
    Abstract: A computed tomography system has a support stage constructed and arranged to support a subject while under observation, an x-ray illumination system arranged proximate the support stage to illuminate the subject with x-rays, an x-ray detection system arranged proximate the support stage to detect x-rays after they pass through the subject and to provide signals based on the detected x-rays, and a data processing system in communication with the x-ray detection system to receive the signals from the x-ray detection system. The computed tomography system has a dynamic mode of operation and a scanning mode of operation. The data processing system extracts information concerning a dynamic process of the subject based on signals from both the dynamic mode and the scanning mode of operation.
    Type: Grant
    Filed: September 29, 2008
    Date of Patent: December 24, 2013
    Assignees: The Johns Hopkins University, Toshiba Medical Systems Corporation
    Inventors: Albert Clark Lardo, Richard T. George, Joao A. C. Lima, Eduardo T. Marban, Takashi Ichihara
  • Publication number: 20130243301
    Abstract: An image processing apparatus according to the present embodiment includes a correcting unit. The correcting unit identifies, based on an observation value of a residual contrast material component that is injected to a subject before a predetermined timing and remains in the subject, the residual contrast material component and a new contrast material component that is newly injected to the subject after the predetermined timing regarding a contrast material component that is included in an image, and corrects an observation value of the contrast material component included in the image.
    Type: Application
    Filed: May 3, 2013
    Publication date: September 19, 2013
    Applicant: Toshiba Medical Systems Corporation
    Inventors: Takuya SAKAGUCHI, Takashi ICHIHARA, Jingwu YAO, Richard T. GEORGE, Jeff TROST, Omair Khwaja YOUSUF, Joao A. C. LIMA
  • Patent number: 8498462
    Abstract: An image processing apparatus includes a storage unit which stores volume data associated with an area including a contrast-enhanced artery as an examination target, a first calculation unit which calculates a plurality of partial atherosclerotic indexes associated with a plurality of portions of the artery on the basis of morphological information associated with the artery which is obtained from the volume data, a second calculation unit which calculates a whole atherosclerotic index associated with the entire artery including the plurality of portions on the basis of the morphological information associated with the artery, and a display unit which displays evaluation information based on the calculated whole atherosclerotic index.
    Type: Grant
    Filed: September 24, 2008
    Date of Patent: July 30, 2013
    Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins University
    Inventors: Hiroyuki Niinuma, Kakuya Kitagawa, Joao A. C. Lima, Yasuko Fujisawa, Miwa Okumura
  • Patent number: 8208703
    Abstract: A motion function of a biological tissue is efficiently evaluated on the basis of image data collected from different medical image diagnostic apparatuses. In terms of a common analysis algorithm applied to subject's time-series image data supplied from a separate medical image diagnostic apparatus, a setting part sets a plurality of interest points on a myocardial tissue of a reference image data extracted from the image data, and a tracking process part measures a motion parameter on the basis of displacement information of the myocardial tissue at the interest points obtained by a tracking process between the reference image data and subsequent image data thereof. Meanwhile, a data creating unit creates parameter image data showing two-dimension distribution of the motion parameter or parameter time-series data showing a variation in time of the motion parameter as parameter data on the basis of the measurement result, and displays the parameter data.
    Type: Grant
    Filed: November 5, 2008
    Date of Patent: June 26, 2012
    Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins University
    Inventors: Tetsuya Kawagishi, Hiroyuki Ohuchi, Yasuhiko Abe, Thomas Helle-Valle, Joao A. C. Lima
  • Publication number: 20120155737
    Abstract: In one embodiment, an image processing apparatus includes a difference image generating unit and a display controlling unit. The difference image generating unit generates a difference image by calculating a difference in a second X-ray transmission image from a first X-ray transmission image, the second X-ray transmission image being an image in which a myocardial tissue of an examined subject is not opacified and the first X-ray transmission image being an image in which the myocardial tissue of the examined subject is opacified with a contrast agent that has been injected into a coronary artery. The display controlling unit exercises control so that a predetermined display unit displays the difference image that has been generated by the difference image generating unit.
    Type: Application
    Filed: December 20, 2010
    Publication date: June 21, 2012
    Applicants: THE JOHNS HOPKINS UNIVERSITY, TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventors: Takuya SAKAGUCHI, Hisato Takemoto, Joao A. C. Lima, Richard T. George, Jeff Trost
  • Patent number: 8160338
    Abstract: An apparatus includes a transformation table acquiring unit, a blood-flow information acquisition unit and a blood-flow image generating unit. The transformation table acquiring unit obtains a transformation table for transforming unspecified information representing a concentration of a contrast medium in a myocardium into an unspecified blood flow value image based on a CT image acquired in a concentration transition period. The blood-flow information acquisition unit obtains information representing the concentration of the contrast medium based on a CT image acquired during a constant concentration period. The blood-flow image generating unit generates a blood flow value image based on the information representing the concentration of the contrast medium according to the transformation table.
    Type: Grant
    Filed: May 20, 2008
    Date of Patent: April 17, 2012
    Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins University
    Inventors: Takashi Ichihara, Richard T. George, Joao A. C. Lima, Albert C. Lardo
  • Publication number: 20110110488
    Abstract: A computed tomography system has a support stage constructed and arranged to support a subject while under observation, an x-ray illumination system arranged proximate the support stage to illuminate the subject with x-rays, an x-ray detection system arranged proximate the support stage to detect x-rays after they pass through the subject and to provide signals based on the detected x-rays, and a data processing system in communication with the x-ray detection system to receive the signals from the x-ray detection system. The computed tomography system has a dynamic mode of operation and a scanning mode of operation. The data processing system extracts information concerning a dynamic process of the subject based on signals from both the dynamic mode and the scanning mode of operation.
    Type: Application
    Filed: September 29, 2008
    Publication date: May 12, 2011
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Albert Clark Lardo, Richard T. George, Joao A.C. Lima, Eduardo Marban
  • Patent number: 7853309
    Abstract: An X-ray CT apparatus comprises a blood-flow information acquisition unit, a correction value calculating unit and a blood-flow image generating unit. The blood-flow information acquisition unit obtains information of a relative blood flow rate in the myocardium of the subject based on the CT image. The correction value calculating unit obtains a correction value based on the CT image in a concentration transition period defined to be a period from immediately after start of a continuous injection of a contrast medium into the subject until the contrast medium reaching the myocardium increases and is be in a state where it can be considered that the contrast medium is saturated at a constant value. The blood-flow image generating unit generates a blood flow value image in the myocardium by correcting the information of the relative blood flow rate with the correction value.
    Type: Grant
    Filed: March 10, 2005
    Date of Patent: December 14, 2010
    Assignees: Toshiba Medical Systems Corporation, The Johns Hopkins University
    Inventors: Takashi Ichihara, Toshihiro Rifu, Joao A. C. Lima, Richard T. George, Albert C. Lardo
  • Publication number: 20100111380
    Abstract: A motion function of a biological tissue is efficiently evaluated on the basis of image data collected from different medical image diagnostic apparatuses. In terms of a common analysis algorithm applied to subject's time-series image data supplied from a separate medical image diagnostic apparatus, a setting part sets a plurality of interest points on a myocardial tissue of a reference image data extracted from the image data, and a tracking process part measures a motion parameter on the basis of displacement information of the myocardial tissue at the interest points obtained by a tracking process between the reference image data and subsequent image data thereof. Meanwhile, a data creating unit creates parameter image data showing two-dimension distribution of the motion parameter or parameter time-series data showing a variation in time of the motion parameter as parameter data on the basis of the measurement result, and displays the parameter data.
    Type: Application
    Filed: November 5, 2008
    Publication date: May 6, 2010
    Inventors: Tetsuya Kawagishi, Hiroyuki Ohuchi, Yasuhiko Abe, Thomas Helle-Valle, Joao A. C. Lima
  • Publication number: 20090268954
    Abstract: An image processing apparatus includes a storage unit which stores volume data associated with an area including a contrast-enhanced artery as an examination target, a first calculation unit which calculates a plurality of partial atherosclerotic indexes associated with a plurality of portions of the artery on the basis of morphological information associated with the artery which is obtained from the volume data, a second calculation unit which calculates a whole atherosclerotic index associated with the entire artery including the plurality of portions on the basis of the morphological information associated with the artery, and a display unit which displays evaluation information based on the calculated whole atherosclerotic index.
    Type: Application
    Filed: September 24, 2008
    Publication date: October 29, 2009
    Inventors: Hiroyuki NIINUMA, Kakuya KITAGAWA, Joao A.C. LIMA, Yasuko FUJISAWA, Miwa OKUMURA
  • Publication number: 20090129536
    Abstract: An apparatus includes a transformation table acquiring unit, a blood-flow information acquisition unit and a blood-flow image generating unit. The transformation table acquiring unit obtains a transformation table for transforming unspecified information representing a concentration of a contrast medium in a myocardium into an unspecified blood flow value image based on a CT image acquired in a concentration transition period. The blood-flow information acquisition unit obtains information representing the concentration of the contrast medium based on a CT image acquired during a constant concentration period. The blood-flow image generating unit generates a blood flow value image based on the information representing the concentration of the contrast medium according to the transformation table.
    Type: Application
    Filed: May 20, 2008
    Publication date: May 21, 2009
    Applicants: TOSHIBA MEDICAL SYSTEMS CORPORATION, THE JOHNS HOPKINS UNIVERSITY
    Inventors: Takashi Ichihara, Richard T. George, Joao A.C. Lima, Albert C. Lardo
  • Patent number: 6408202
    Abstract: A method of transesophageal magnetic resonance analysis of a patient, such as an animal or human, includes providing a loopless antenna formed from a flexible coaxial cable having an extended center conductor at the distal end thereof. A distal portion of the loopless antenna is secured within a Levin-type gastric tube. The gastric tube which receives the loopless antenna is inserted in the esophagus of the patient. A tuning, matching and decoupling circuit for the loopless antenna is employed external to the patient. The tuning, matching and decoupling circuit is electrically connected to a magnetic resonance imaging scanner. The magnetic resonance imaging scanner is employed to display an image of the aorta of the patient.
    Type: Grant
    Filed: November 3, 1999
    Date of Patent: June 18, 2002
    Assignee: The Johns Hopkins University
    Inventors: Joao A. C. Lima, Kendrick A. Shunk, Ergin Atalar