Patents by Inventor Joao Aguiar

Joao Aguiar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • sporozoite and liver stage antigens
    Patent number: 9694062
    Abstract: The invention provides novel malaria polypeptides expressed at the pre-erythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: July 4, 2017
    Assignee: The United States of America as Represented by the Secretary of the Navy
    Inventors: Joao Aguiar, Keith Limbach, Martha Sedegah, Thomas Richie
  • PLASMODIUM FALCIPARUM SPOROZOITE AND LIVER STAGE ANTIGENS
    Publication number: 20150265690
    Abstract: The invention provides novel malaria polypeptides expressed at the pre-erythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.
    Type: Application
    Filed: March 19, 2014
    Publication date: September 24, 2015
    Inventors: JOAO AGUIAR, KEITH LIMBACH, MARTHA SEDEGAH, THOMAS RICHIE
  • Compositions and methods for modifying gene expression using the promoter of ubiquitin conjugating protein coding gene of soybean plants
    Patent number: 9012720
    Abstract: A polynucleotide isolated from soybean plants capable of initiating transcription and with sequence identity to SEQ ID No. 1 is provided. In some aspects, the polynucleotide has sequence identity to SEQ ID No. 1 of at least 40%, is the reverse complement or the reverse of such sequences. In some aspects, the polynucleotide is linked to expression enhancers or sequences of interest. In some embodiments, a recombinant vector comprises the polynucleotide. In some aspects, the recombinant vector comprises enhancers, termination sequences, or sequences of interest. In some embodiments a transformed cell, plant, plant part, or propagulum comprise the polynucleotide.
    Type: Grant
    Filed: February 19, 2013
    Date of Patent: April 21, 2015
    Assignee: Empresa Brasileira de Pesquisa Agropecuaria
    Inventors: Maria Fatima Grossi de Sa, Luciane Mourao Guimaraes, Joao Aguiar Nogueira Batista, Antonio Americo Barbosa Viana, Rodrigo da Rocha Fragoso, Maria Cristina Mattar da Silva
  • Compositions and methods for modifying gene expression using the promoter of ubiquitin conjugating protein coding gene of cotton plants
    Patent number: 8227588
    Abstract: The present Invention relates to regulatory sequences of polynucleotides isolated from cotton plants capable of initiating and activating the transcription of polynucleotides, and the use of these regulatory sequences for modifying the transcription of endogenous and/or heterologous polynculeotides and the production of polypeptides.
    Type: Grant
    Filed: January 21, 2008
    Date of Patent: July 24, 2012
    Assignee: Empresa Brasileira de Pesquisa Agropecuaria
    Inventors: Maria Fatima Grossi de Sa, Luciane Mourão Guimarães, João Aguiar Nogueira Batista, Antonio Américo Barbosa Viana, Rodrigo da Rocha Fragoso, Thales Lima Rocha
  • Plasmodium falciparum sporozoite and liver stage antigens
    Publication number: 20110104195
    Abstract: The invention provides novel malaria polypeptides expressed at the pre-erythrocytic stage of the malaria life-cycle. The antigens can be utilized to induce an immune response against malaria in a mammal by administering the antigens in vaccine formulations or expressing the antigens in DNA or other nucleic acid expression systems delivered as a vaccine formulation.
    Type: Application
    Filed: November 3, 2010
    Publication date: May 5, 2011
    Inventors: Joao Aguiar, Keith Limbach, Martha Sedagah, Thomas Richie
  • COMPOSITIONS AND METHODS FOR MODIFYING GENE EXPRESSION USING THE PROMOTER OF UBIQUITIN CONJUGATING PROTEIN CODING GENE OF SOYBEAN PLANTS
    Publication number: 20100005539
    Abstract: A polynucleotide isolated from soybean plants capable of initiating transcription and with sequence identity to SEQ ID No.1 is provided. In some aspects, the polynucleotide has sequence identity to SEQ ID No. 1 of at least 40%, is the reverse complement or the reverse of such sequences. In some aspects, the polynucleotide is linked to expression enhancers or sequences of interest. In some embodiments, a recombinant vector comprises the polynucleotide. In some aspects, the recombinant vector comprises enhancers, termination sequences, or sequences of interest. In some embodiments a transformed cell, plant, plant part, or propagulum comprise the polynucleotide.
    Type: Application
    Filed: January 21, 2008
    Publication date: January 7, 2010
    Applicant: Empresa Brasileira de Pesquisa Agropecuaria
    Inventors: Maria Fatima Grossi de Sa, Luciane Mourão Guimarães, João Aguiar Nogueira Batista, Antonio Américo Barbosa Viana, Rodrigo da Rocha Fragoso, Maria Cristina Mattar da Silva
  • COMPOSITIONS AND METHODS FOR MODIFYING GENE EXPRESSION USING THE PROMOTER OF UBIQUITIN CONJUGATING PROTEIN CODING GENE OF COTTON PLANTS
    Publication number: 20090320153
    Abstract: A polynucleotide isolated from cotton plants capable of initiating transcription and with sequence identity to SEQ ID No.1 is provided. In some aspects, the polynucleotide has sequence identity to SEQ ID No. 1 of at least 40%, is the reverse complement or the reverse of such sequences. In some aspects, the polynucleotide is linked to expression enhancers or sequences of interest. In some embodiments, a recombinant vector comprises the polynucleotide. In some aspects, the recombinant vector comprises enhancers, termination sequences, or sequences of interest. In some embodiments a transformed cell, plant, plant part, or propagulum comprise the polynucleotide.
    Type: Application
    Filed: January 21, 2008
    Publication date: December 24, 2009
    Applicant: Empresa Brasileira de Pesquisa Agropecuaria
    Inventors: Maria Fatima Grossi de Sa, Luciane Mourão Guimarães, João Aguiar Nogueira Batista, Antonio Américo Barbosa Viana, Rodrigo da Rocha Fragoso, Thales Lima Rocha