Patents by Inventor Joao B. Calixto

Joao B. Calixto has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Active fraction of a polar solvent extract from the latex of euphorbiaceae plants
    Patent number: 10143673
    Abstract: The present invention generally refers to an active fraction of an extract of the latex of plants from the family Euphorbiaceae in a polar solvent, as well as of one or more compounds contained therein, as well as the use of said fraction and/or said compounds, particularly in the treatment of cancer. The invention also refers to compositions comprising said active fraction and/or said compounds, as well as their use for the treatment of diseases concerning cell proliferation/angiogenesis, particularly cancer.
    Type: Grant
    Filed: May 19, 2015
    Date of Patent: December 4, 2018
    Assignee: AMAZONIA FITOMEDICAMENTOS LTDA.
    Inventors: Luiz F. Pianowski, Claudio P. Chaves, Joao B. Calixto
  • ACTIVE FRACTION OF A POLAR SOLVENT EXTRACT FROM THE LATEX OF EUPHORBIACEAE PLANTS
    Publication number: 20150359774
    Abstract: The present invention generally refers to an active fraction of an extract of the latex of plants from the family Euphorbiaceae in a polar solvent, as well as of one or more compounds contained therein, as well as the use of said fraction and/or said compounds, particularly in the treatment of cancer. The invention also refers to compositions comprising said active fraction and/or said compounds, as well as their use for the treatment of diseases concerning cell proliferation/angiogenesis, particularly cancer.
    Type: Application
    Filed: May 19, 2015
    Publication date: December 17, 2015
    Applicant: AMAZONIA FITOMEDICAMENTOS LTDA.
    Inventors: Luiz F. PIANOWSKI, Claudio P. CHAVES, Joao B. CALIXTO
  • ACTIVE FRACTION OF A POLAR SOLVENT EXTRACT FROM THE LATEX OF EUPHORBIACEAE PLANTS
    Publication number: 20090142421
    Abstract: The present invention generally refers to an active fraction of an extract of the latex of plants from the family Euphorbiaceae in a polar solvent, as well as of one or more compounds contained therein, as well as the use of said fraction and/or said compounds, particularly in the treatment of cancer. The invention also refers to compositions comprising said active fraction and/or said compounds, as well as their use for the treatment of diseases concerning cell proliferation/angiogenesis, particularly cancer.
    Type: Application
    Filed: June 28, 2005
    Publication date: June 4, 2009
    Applicant: AMAZONIA FITOMEDICAMENTOS LTDA.
    Inventors: Luiz F. Pianowski, Claudio P. Chaves, Joao B. Calixto
  • Use of Carophyllenes in the Manufacture of Medicaments and Treatment of Bodily Conditions of Inflammation and Inflammatory Pain
    Publication number: 20080280996
    Abstract: The invention concerns the use of caryophyllenes related to medicaments and to the treatment of bodily conditions of inflammation and inflammatory pain.
    Type: Application
    Filed: October 1, 2004
    Publication date: November 13, 2008
    Inventors: Luiz F. Pianowski, Joao B. Calixto, Dagoberto de C. Brandao
  • Specific steady-state R-type CA channel blockers and use thereof
    Patent number: 7109175
    Abstract: The present invention relates to Ca2+ channel blockers and more particularly to the R-type Ca2+ channel blockers. More specifically, the invention relates to Ca2+ channel blockers activity of Mandevilla velutina and Mandevilla illustris. The present invention further concerns saponin-like compounds isolated from Mandevilla species. The present invention also relates to the treatment of several pathologies that involve the nifedipine-insensitive but isradipine sensitive steady-state R-type Ca2+ channel and the use of steady-state R-type Ca2+ channel blockers in the treatment of these pathologies.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: September 19, 2006
    Assignee: Universite de Sherbrooke
    Inventors: Ghassan Bkaily, Pedro D'Orleans-Juste, Joao B. Calixto, Rosendo A. Yunes