Patents by Inventor Joao Bandarra

Joao Bandarra has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the manufacture of iohexol
    Patent number: 7541494
    Abstract: A process for the production of iohexol comprises alkylating 5-Acetamido-N,N?-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide using 2(2-methoxy-ethoxy)-ethanol as solvent in the presence of a base, and optionally isolating crude iohexol from the reaction mixture. Preferably, the alkylating agent is 1-chloro-2,3 propanediol and the base is an alkali metal hydroxide such as sodium hydroxide or potassium hydroxide.
    Type: Grant
    Filed: March 3, 2006
    Date of Patent: June 2, 2009
    Assignee: Hovione Inter Ltd.
    Inventors: José Galindro, Susana Marto, João Bandarra, William Heggie
  • Process for the manufacture of iohexol
    Publication number: 20090048463
    Abstract: A process for the production of iohexol comprises alkylating 5-Acetamido-N,N?-bis(2,3-dihydroxypropyl)-2,4,6-triiodoisophthalamide using 2(2-methoxy-ethoxy)-ethanol as solvent in the presence of a base, and optionally isolating crude iohexol from the reaction mixture. Preferably, the alkylating agent is 1-chloro-2,3 propanediol and the base is an alkali metal hydroxide such as sodium hydroxide or potassium hydroxide.
    Type: Application
    Filed: March 3, 2006
    Publication date: February 19, 2009
    Inventors: Jose Galindro, Susana Marto, Joao Bandarra, William Heggie
  • Process for the preparation of mometasone furoate
    Patent number: 6177560
    Abstract: The invention provides a new process for the preparation of mometasone 17-furoate, a steroid derivative useful in the treatment of inflammatory disease, by direct esterification of the 17 hydroxyl group without prior protection of the free 11 hydroxy function.
    Type: Grant
    Filed: December 29, 1999
    Date of Patent: January 23, 2001
    Assignee: Hovione Inter Ltd.
    Inventors: William Heggie, Joao Bandarra