Abstract: A system and method for estimating LV filling pressure of the heart of a human patient. The system includes a data processing apparatus, an imaging system for non-invasively obtaining images of the patient's heart and for providing imaging data to the data processing apparatus, and a data input device for receiving patient specific parameters relating to BMI and systolic arterial blood pressure of the patient and for providing the patient specific parameters to the data processing apparatus. The data processing apparatus is configured to perform the method including the steps of using the imaging data and the patient specific parameters, determining an estimate of the minimum LV diastolic pressure, estimating the peak pressure drop and obtaining a maximum difference between the LA pressure and LV pressure, and calculating an estimate of the LV filling pressure.

Abstract: A method for determining an internal myocardial power of a heart, the method comprising non-invasively obtaining one or more first images that are indicative of a structure of the heart, non-invasively obtaining one or more second images that are indicative of a flow property of the heart, segmenting, based on the one or more first images, the blood pool and the myocardium of the heart, determining, based on the segmented 5 blood pool, the myocardium and the one or more second images, one or more mechanical parameters of the heart, and determining the internal myocardial power based on the one or more mechanical parameters.

Abstract: The disclosure refers to a method for non-invasively determining a pressure difference in a cardiovascular vessel, comprising providing imaging data indicative of imaging signals detected in a region of interest of a cardiovascular vessel, the region comprising a proximal vessel portion, a distal vessel portion, and a vessel narrowing located between the proximal and the distal vessel; and determining, from the imaging data, a pressure difference between a first location and a second location in the cardiovascular vessel portion, the first location and the second location provided in the proximal and the distal vessel portions, respectively.