Abstract: The present invention relates to certain derivatives of cycloalkanediones invariably substituted with a chroman-2-yl, 2-quinolyl or —O-phenyl residue which are serotonin (5-hydroxytryptamine, 5-HT) 5-HT1A receptor subtype agonists modulators, to their stereochemical isomers and to their use in the preparation of a medicament for the treatment of pathological states for which an agonist a modulator of these receptors is indicated.

Abstract: New cycloalkanedione derivatives that are serotonin (5-hydroxytriptamine, 5-HT) 5-HT1A receptor subtype agonists and, consequently, they are useful in the treatment of pathological states for which an agonist of these receptors is indicated. They are particularly useful as neuroprotective agents, of special interest in the treatment and prophylaxis of cerebral damage produced by traumatic or ischemic stroke.

Abstract: New cycloalkanedione derivatives that are serotonin (5-hydroxytriptamine, 5-HT) 5-HT1A receptor subtype agonists and, consequently, they are useful in the treatment of pathological states for which an agonist of these receptors is indicated. They are particularly useful as neuroprotective agents, of special interest in the treatment and prophylaxis of cerebral damage produced by traumatic or ischemic stroke.

Abstract: This invention provides new benzothiophene derivatives of general formula (I) and a process for preparing them, the corresponding compositions and their use for manufacturing a medicine for the treatment of neurological disorders. These new compounds behave as serotonin reuptake inhibitors and show high affinity towards the 5-HT1A receptor.

Abstract: Benzothiophene derivative compounds and corresponding use and composition; the compounds respond to formula (I): where Z is: —CO—, —CH(OR6)—, —C(NOR7)—; R1 is: H, C1-C6 alkyl, halogen, or —OR8; R2 and R3 are: H, alkyl, halogen, —OR8, nitro, cyano, NR9R10; —COR8; CO2R8; —SO2NR9R10; —SO2R8; —SR8; —CONR9R10; R4 and R5 are: H, alkyl, halogen, haloalkyl, —OR8, nitro, NR9R10; —COR8; CO2R8; —SO2NR9R10; —SO2R8; SR8, cyano; —CONR9R10 or R4 and R5 form a benzene ring; R6 is: H, alkyl, CO2R8, —C(O)NR9R10, naphthyl or phenyl; R7 is: H or alkyl; R8 is H, C1-C6 alkyl or phenyl; R9 and R10 are: H, alkyl or phenyl or R9 and R10 form a 5- or 6-membered ring. These compounds are effective for the treatment of anxiety or depression.