Patents by Inventor Joaquin Lopez
Joaquin Lopez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11940578Abstract: An imaging method including: a) acquiring N successive positron emission tomography (PET) low resolution images ?i and simultaneously, N successive Ultrafast Ultrasound Imaging (UUI) images Ui of a moving object; b) determining from each UUI image Ui, the motion vector fields Mi that corresponds to the spatio-temporal geometrical transformation of the motion of the object; c) obtaining a final estimated high resolution image H of the object by iterative determination of a high resolution image Hn+1 obtained by applying several correction iterations to a current estimated high resolution image Hn, n being the number of iterations, starting from an initial estimated high resolution image H1 of the object, each correction iteration including at least: i) warping the estimated high resolution image Hn using the motion vector fields Mi to determine a set of low resolution reference images Lni; ii) determining a differential image Di by difference between each PET image ?i and the corresponding low resolution reType: GrantFiled: January 28, 2021Date of Patent: March 26, 2024Assignees: INSERM (INSTITUT NATIONAL DE LA SANTÉ ET DE LA RECHERCHE MÉDICALE), UNIVERSITÉ DE PARIS, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE—CNRS, ECOLE SUPERIEURE DE PHYSIQUE ET DE CHIMIE INDUSTRIELLES DE LA VILLE DE PARISInventors: Bertrand Tavitian, Mickaël Tanter, Mailyn Perez-Liva, Joaquin Lopez Herraiz, Jean Provost
-
Publication number: 20210239863Abstract: An imaging method including: a) acquiring N successive positron emission tomography (PET) low resolution images ?i and simultaneously, N successive Ultrafast Ultrasound Imaging (UUI) images Ui of a moving object; b) determining from each UUI image Ui, the motion vector fields Mi that corresponds to the spatio-temporal geometrical transformation of the motion of the object; c) obtaining a final estimated high resolution image H of the object by iterative determination of a high resolution image Hn+1 obtained by applying several correction iterations to a current estimated high resolution image Hn, n being the number of iterations, starting from an initial estimated high resolution image H1 of the object, each correction iteration including at least: i) warping the estimated high resolution image Hn using the motion vector fields Mi to determine a set of low resolution reference images Lni; ii) determining a differential image Di by difference between each PET image ?i and the corresponding low resolution reType: ApplicationFiled: January 28, 2021Publication date: August 5, 2021Inventors: Bertrand TAVITIAN, Mickaël TANTER, Mailyn PEREZ-LIVA, Joaquin LOPEZ HERRAIZ, Jean PROVOST
-
Patent number: 10390775Abstract: A method and system for acquiring a series of medical images includes receiving medical imaging data corresponding to photons emitted from a subject having received a dose of a radiotracer. Determining, from the medical imaging data, coincidence events including photon coincidence events involving two photons and photon coincidence events involving more than two photons. The photon coincidence events involving two photons and photon coincidence events involving more than two photons are processed and use to reconstruct a series of medical images of the subject.Type: GrantFiled: November 7, 2013Date of Patent: August 27, 2019Assignee: Massachusetts Institute of TechnologyInventors: Eduardo M. Lage, Joaquin Lopez Herraiz, Vicente Jose Parot, Shivang R. Dave
-
Patent number: 9453031Abstract: Provided are chemical entities selected from compounds of formula (I), wherein R1, R2 and m have meanings given in the description, and pharmaceutically acceptable salts, solvates and stereoisomers thereof, which are inhibitors of ATR and are potentially useful in the treatment of cancer. Further provided are pharmaceutical compositions of the chemical entities, combination products containing the chemical entities, the use of the compositions as therapeutic agents, and methods of treatment using these compositions.Type: GrantFiled: March 14, 2014Date of Patent: September 27, 2016Assignee: Fundación Centro Nacional de Investigaciones Oncológicas Carlos IIIInventors: Joaquín Pastor Fernández, Oscar Fernández-Capetillo Ruiz, Sonia Martínez González, Carmen Blanco Aparicio, María del Rosario Rico Ferreira, Luis Ignacio Toledo Lázaro, Sonsoles Rodríguez Arísteguí, Matilde Murga Costa, Carmen Varela Busto, Andrés Joaquín Lopez Contreras, Oliver Renner, María Nieto Soler, David Alvaro Cebrián Muñoz
-
Publication number: 20160024112Abstract: Provided are chemical entities selected from compounds of formula (I), wherein R1, R2 and m have meanings given in the description, and pharmaceutically acceptable salts, solvates and stereoisomers thereof, which are inhibitors of ATR and are potentially useful in the treatment of cancer. Further provided are pharmaceutical compositions of the chemical entities, combination products containing the chemical entities, the use of the compositions as therapeutic agents, and methods of treatment using these compositions.Type: ApplicationFiled: March 14, 2014Publication date: January 28, 2016Inventors: Joaquín Pastor Fernández, Oscar Fernández-Capetillo Ruiz, Sonia Martínez González, Carmen Blanco Aparicio, María del Rosario Rico Ferreira, Luis Ignacio Toledo Lázaro, Sonsoles Rodríguez Arísteguí, Matilde Murga Costa, Carmen Varela Busto, Andrés Joaquín Lopez Contreras, Oliver Renner, María Nieto Soler, David Alvaro Cebrián Muñoz
-
Publication number: 20150289825Abstract: A method and system for acquiring a series of medical images includes receiving medical imaging data corresponding to photons emitted from a subject having received a dose of a radiotracer. Determining, from the medical imaging data, coincidence events including photon coincidence events involving two photons and photon coincidence events involving more than two photons. The photon coincidence events involving two photons and photon coincidence events involving more than two photons are processed and use to reconstruct a series of medical images of the subject.Type: ApplicationFiled: November 7, 2013Publication date: October 15, 2015Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGYInventors: Eduardo M. LAGE, Joaquin Lopez HERRAIZ, Vicente Jose PAROT, Shivang R. DAVE
-
Publication number: 20150240297Abstract: Procedure for obtaining a marker of objects to be identified, comprising at least one polymorphic DNA fragment and preferably a plurality of polymorphic DNA fragments, such as microsatellite or single base polymorphism, modified in their three-dimensional structure, adsorbed to metallic nanoparticles and micro encapsulated, which are active to Raman radiation. Said marker is also protected; as well as the marker detection method; the method to instantly authenticate marked objects with the said marker; the method to verify the marked objects with the said marker and the method for incorporating the said marker to the desired object to be identified.Type: ApplicationFiled: July 31, 2012Publication date: August 27, 2015Inventors: Juan Carlos Jaime, Rubén Simonetta, Mauricio Naranjo, Joaquin Lopez
-
Patent number: 8154284Abstract: An NMR method is presented having enhanced sensitivity on a compound comprising hyperpolarizable nuclei, in particular applying enhanced PHIP. Polarization is thereby transferred from a prepared fluid, which is enriched with symmetric molecules of a particular spin state (e.g. para-hydrogen enriched), directly to the hyperpolarizable nuclei of a compound, without altering the chemical identity of the compound in this process. Spin transfer is achieved using a template having sites of ordered environment, and the fluid and the compound are brought together in the presence of the template. Polarization transfer to the hyperpolarizable nuclei of the compound is thereby easier to perform and can be applied to a broader scope of compounds.Type: GrantFiled: June 17, 2008Date of Patent: April 10, 2012Assignee: University of YorkInventors: Simon Benedict Duckett, Gary George Green, Paul Ian Elliott, Joaquin Lopez-Serrano
-
Publication number: 20100219826Abstract: An NMR method is presented having enhanced sensitivity on a compound comprising hyperpolarizable nuclei, in particular applying enhanced PHIP. Polarization is thereby transferred from a prepared fluid, which is enriched with symmetric molecules of a particular spin state (e.g. para-hydrogen enriched), directly to the hyperpolarizable nuclei of a compound, without altering the chemical identity of the compound in this process. Spin transfer is achieved using a template having sites of ordered environment, and the fluid and the compound are brought together in the presence of the template. Polarization transfer to the hyperpolarizable nuclei of the compound is thereby easier to perform and can be applied to a broader scope of compounds.Type: ApplicationFiled: June 17, 2008Publication date: September 2, 2010Inventors: Simon Benedict Duckett, Gary George Green, Paul Ian Elliott, Joaquin Lopez-Serrano
-
Patent number: 5644216Abstract: In order to give the current the quality of low sensitivity to temperature, a first MOS transistor and a second MOS transistor supplied by a current mirror have their sources connected to the ground, with the drain and the gate of the first transistor being connected to the gate of the second transistor by means of a resistor. The quotient of the dimensional ratios of the transistors is equal to the coefficient of the current mirror and the transistors are doped so that the threshold of the second transistor is greater than that of the first one. Application notably to ramp generators for the programming of EEPROM cells.Type: GrantFiled: May 31, 1995Date of Patent: July 1, 1997Assignee: SGS-Thomson Microelectronics, S.A.Inventors: Joaquin Lopez, Jean-Michel Coquin