Patents by Inventor Jochen Antel

Jochen Antel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Benzazepine-, benzoxazepine- and benzothiazepine-n-acetic acid derivatives, process for their preparation and pharmaceutical compositions containing them
    Patent number: 5677297
    Abstract: Compounds with neutral endopeptidase (NEP) inhibitory activity corresponding to the formula I ##STR1## in which R.sup.1 is a lower alkoxy-lower-alkyl group whose lower alkoxy radical is substituted by a lower alkoxy group, or a phenyl-lower-alkyl or phenyloxy-lower-alkyl group which can optionally be substituted in the phenyl ring by lower alkyl, lower alkoxy or halogen, or a naphthyl-lower-alkyl group,A is CH.sub.2, O or S,R.sup.2 is hydrogen or halogen,R.sup.3 is hydrogen or halogen,R.sup.4 is hydrogen or a group forming a biolabile ester, andR.sup.5 is hydrogen or a group forming a biolabile ester, and the physiologically acceptable acid addition salts thereof.
    Type: Grant
    Filed: March 22, 1996
    Date of Patent: October 14, 1997
    Assignee: Solvay Pharmaceuticals GmbH
    Inventors: Harald Waldeck, Dagmar Hoeltje, Josef Messinger, Jochen Antel, Michael Wurl, Dirk Thormaehlen