Patents by Inventor Jochen Keupp

Jochen Keupp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11899083
    Abstract: The present invention is directed to a RF transmit system (1) for a magnetic resonance examination system where it is intended to provide a solution for the problem of rapidly switching between operation modes of different peak power requirements at good power efficiencies. For this purpose the RF transmit system (1) comprises at least one RF channel (14) wherein the RF channel (14) has an RF amplifier (3), at least two power supply devices (4, 5) wherein each of the power supply devices (4, 5) is configured to supply a voltage to the amplifier (3). The RF transmit system (1) further comprises a DC switch (8) configured to switch the voltage supplied to the amplifier (3) between the power supply devices (4, 5) and a controller (2) configured to switch the voltage based on sensor data.
    Type: Grant
    Filed: February 15, 2019
    Date of Patent: February 13, 2024
    Assignee: Koninklijke Philips N.V.
    Inventors: Peter Vernickel, Christoph Leussler, Ingo Schmale, Jochen Keupp
  • Patent number: 11815582
    Abstract: A method of magnet resonance (MR) imaging of an object including: subjecting an object in an examination volume of an MR device to a dual echo steady state imaging sequence, a free induction decay signal (FID) and an echo signal (ECHO) being generated in each interval between two successive RF pulses, wherein a pair of diffusion gradient waveforms (GDIF) of equal phase integral and opposed polarity is applied in the interval between the FID signal and the echo signal; —acquiring the FID signals and the echo signals in a number of repetitions of the imaging sequence with varying phase encoding; and —reconstructing a diffusion weighted MR image from the acquired FID signals and echo signals.
    Type: Grant
    Filed: May 6, 2020
    Date of Patent: November 14, 2023
    Assignee: Koninklijke Philips N.V.
    Inventors: Jochen Keupp, Ulrich Wolfgang Katscher
  • Publication number: 20230148892
    Abstract: Disclosed herein is a method of medical imaging The method comprises: receiving (200) a first electrical properties tomography conductivity map (122) for a first radio frequency value, receiving (202) a second electrical properties tomography conductivity map (124), calculating (204) a low frequency conductivity map (126) using the first electrical properties tomography conductivity map and the second electrical properties tomography conductivity map, calculating (208) an intra-cellular volume map (130) and an extra-cellular volume map (131) by performing an optimization of a two-term exponential model to the multi-b diffusion weighted magnetic resonance imaging signal spectra map, calculating (210) an intra-cellular volume fraction map (132) by performing a voxel wise division of the intra-cellular volume map by the voxel wise sum of the extra-cellular volume map plus the intra-cellular volume map, and calculating (212) an intra-cellular conductivity map (134) by performing a voxel wise division of an interm
    Type: Application
    Filed: March 31, 2021
    Publication date: May 18, 2023
    Inventors: Ulrich Wolfgang Katscher, Jochen Keupp
  • Publication number: 20230028306
    Abstract: The present invention relates to an apparatus (10) for diagnostic image acquisition, comprising: an input unit (20); a processing unit (30); and an output unit (40). The input unit is configured to receive a data value relating to at least one biomarker in a measurement blood sample of a patient. The processing unit is configured to determine a time to acquire a diagnostic image of the patient, wherein the determination comprises utilization of the data value. The output unit is configured to output an indication of the time to acquire the diagnostic image of the patient.
    Type: Application
    Filed: November 17, 2020
    Publication date: January 26, 2023
    Inventors: Pieter Jan van der Zaag, Wilhelmus Franciscus Johannes Verhaegh, Jochen Keupp
  • Patent number: 11474182
    Abstract: A medical imaging system includes a memory for storing machine executable instructions. The medical imaging system further includes a processor for controlling the medical imaging system. Execution of the machine executable instructions causes the processor to: receive magnetic resonance image data acquired according to a CEST magnetic resonance imaging protocol, wherein the magnetic resonance image data includes voxels, wherein each of the voxels includes a measured Z-spectrum for a set of saturation frequency offsets; assign a motion likelihood map to each voxel by comparing the measured Z-spectrum of each voxel to predetermined criteria; and reconstruct a CEST magnetic resonance image using the magnetic resonance image data and the motion likelihood map.
    Type: Grant
    Filed: May 22, 2019
    Date of Patent: October 18, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Jochen Keupp, Elwin De Weerdt
  • Publication number: 20220308148
    Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to enable MR signal acquisition in a single scan providing the necessary information for electric properties imaging (EPT), namely a phase map as well as tissue boundaries. The method of the invention comprises the following steps: —subjecting the object (10) to a multi echo steady state imaging sequence or a fast spectroscopic imaging sequence comprising RF pulses and switched magnetic field gradients, wherein two or more echo signals are generated after each RF excitation; —acquiring the echo signals; —deriving a magnitude image and a phase map from the acquired echo signals, which phase map represents the spatial RF field distribution induced by the RF pulses in the object (10); and —reconstructing an electric conductivity map from the magnitude image and from the phase map, wherein tissue boundaries are derived from at least the magnitude image.
    Type: Application
    Filed: June 19, 2020
    Publication date: September 29, 2022
    Inventors: Ulrich Katscher, Johan Samuel Van Den Brink, Jochen Keupp
  • Publication number: 20220236357
    Abstract: The invention relates to a method of MR imaging of an object (10) placed in an examination volume of a MR device (1). It is an object of the invention to enable distortion-free high-quality diffusion weighted imaging (DWI) with minimization of artefacts caused by motion. The method of the invention comprises the following steps: —subjecting the object (10) to a dual echo steady state imaging sequence, a free induction decay signal (FID) and an echo signal (ECHO) being generated in each interval between two successive RF pulses, wherein a pair of diffusion gradient waveforms (GDIF) of equal phase integral and opposed polarity is applied in the interval between the FID signal and the echo signal; —acquiring the FID signals and the echo signals in a number of repetitions of the imaging sequence with varying phase encoding; and —reconstructing a diffusion weighted MR image from the acquired FID signals and echo signals.
    Type: Application
    Filed: May 6, 2020
    Publication date: July 28, 2022
    Inventors: JOCHEN KEUPP, ULRICH WOLFGANG KATSCHER
  • Patent number: 11353532
    Abstract: The invention relates to a magnetic resonance imaging system (100) for determining an approximation (150) of an electric conductivity distribution within a three-dimensional anatomical structure of interest. The determining comprises acquiring a first set of (3-n)-dimensional magnetic resonance data (144), reconstructing a (3-n)-dimensional phase distribution (146) using the (3-n)-dimensional magnetic resonance data (144), calculating a (3-n)-dimensional electric conductivity distribution (148) using spatial derivatives within the (3-n) dimensions and applying to the (3-n)-dimensional electric conductivity distribution (148) a scaling factor compensating for the relative reduction of dimensions by n.
    Type: Grant
    Filed: March 11, 2019
    Date of Patent: June 7, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Ulrich Katscher, Christian Findelkee, Jochen Keupp
  • Patent number: 11327136
    Abstract: The invention provides for a medical imaging system (100, 300). The medical imaging system comprises a processor (104).
    Type: Grant
    Filed: January 7, 2019
    Date of Patent: May 10, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Jochen Keupp, Holger Eggers
  • Patent number: 11320508
    Abstract: The invention relates to a magnetic resonance imaging data processing system (126) for processing motion artifacts in magnetic resonance imaging data sets using a deep learning network (146, 502, 702) trained for the processing of motion artifacts in magnetic resonance imaging data sets. The magnetic resonance imaging data processing system (126) comprises a memory (134, 136) storing machine executable instructions (161, 164) and the trained deep learning network (146, 502, 702). Furthermore, the magnetic resonance imaging data processing system (126) comprises a processor (130) for controlling the magnetic resonance imaging data processing system.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: May 3, 2022
    Assignee: Koninklijke Philips N.V.
    Inventors: Karsten Sommer, Tom Brosch, Tim Philipp Harder, Jochen Keupp, Ingmar Graesslin, Rafael Wiemker, Axel Saalbach
  • Patent number: 11307277
    Abstract: A medical analysis system (111) for processing magnetic resonance imaging (MRI), data (170) from a target volume (208) in a subject (218) includes a memory (107) for storing machine executable instructions; and a processor (103) for controlling the system (111). Execution of the machine executable instructions causes the processor (103) to: determine from the MRI data (103) chemical exchange saturation transfer (CEST) voxel values corresponding to a transfer of saturation between a predefined pool of protons and water protons, the pool of protons having a predefined chemical shift; and weight the CEST values in order to distinguish CEST values of fluid-rich tissues (507) from CEST values of solid tissues (505) in the target volume (208), wherein the fluid-rich tissue comprises an amount of fluid higher than a predefined minimum amount of fluid.
    Type: Grant
    Filed: January 2, 2019
    Date of Patent: April 19, 2022
    Assignee: Koninklijke Philips N.V.
    Inventor: Jochen Keupp
  • Publication number: 20210215782
    Abstract: The invention provides for a medical imaging system (100, 300) comprising a memory (110) for storing machine executable instructions (120). The medical imaging system further comprises a processor (104) for controlling the medical imaging system. Execution of the machine executable instructions causes the processor to: receive (200) magnetic resonance image data (122) acquired according to a CEST magnetic resonance imaging protocol, wherein the magnetic resonance image data comprises voxels, wherein each of the voxels comprises a measured Z-spectrum (500) for a set of saturation frequency offsets (502, 504, 504?, 506, 506?, 508, 510); assign (202) a motion likelihood map (126) to each voxel by comparing the measured Z-spectrum of each voxel to predetermined criteria; and reconstruct (204) a CEST magnetic resonance image (128) using the magnetic resonance image data and the motion likelihood map.
    Type: Application
    Filed: May 22, 2019
    Publication date: July 15, 2021
    Inventors: JOCHEN KEUPP, ELWIN DE WEERDT
  • Publication number: 20210186588
    Abstract: The invention provides for a medical system (100, 300, 400, 500) comprising: a memory (110) for storing machine executable instructions (150) and a processor (104) for controlling the medical system.
    Type: Application
    Filed: March 16, 2018
    Publication date: June 24, 2021
    Inventors: ULRICH KATSCHER, JOCHEN KEUPP, HOLGER GRUELL, EDWIN HEIJMAN, SIN YUIN YEO
  • Publication number: 20210181287
    Abstract: The invention relates to a magnetic resonance imaging data processing system (126) for processing motion artifacts in magnetic resonance imaging data sets using a deep learning network (146, 502, 702) trained for the processing of motion artifacts in magnetic resonance imaging data sets. The magnetic resonance imaging data processing system (126) comprises a memory (134, 136) storing machine executable instructions (161, 164) and the trained deep learning network (146, 502, 702). Furthermore, the magnetic resonance imaging data processing system (126) comprises a processor (130) for controlling the magnetic resonance imaging data processing system.
    Type: Application
    Filed: October 22, 2018
    Publication date: June 17, 2021
    Inventors: KARSTEN SOMMER, TOM BROSCH, TIM PHILIPP HARDER, JOCHEN KEUPP, INGMAR GRAESSLIN, RAFAEL WIEMKER, AXEL SAALBACH
  • Patent number: 10997726
    Abstract: The invention provides for a medical instrument (100, 300, 400) comprising: a memory (110) for storing machine executable instructions (112) and a processor (106) for controlling the medical instrument.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: May 4, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Bernhard Gleich, Jorn Borgert, Jochen Keupp
  • Publication number: 20210116522
    Abstract: The present invention is directed to a RF transmit system (1) for a magnetic resonance examination system where it is intended to provide a solution for the problem of rapidly switching between operation modes of different peak power requirements at good power efficiencies. For this purpose the RF transmit system (1) comprises at least one RF channel (14) wherein the RF channel (14) has an RF amplifier (3), at least two power supply devices (4, 5) wherein each of the power supply devices (4, 5) is configured to supply a voltage to the amplifier (3). The RF transmit system (1) further comprises a DC switch (8) configured to switch the voltage supplied to the amplifier (3) between the power supply devices (4, 5) and a controller (2) configured to switch the voltage based on sensor data.
    Type: Application
    Filed: February 15, 2019
    Publication date: April 22, 2021
    Applicant: Koninklijke Philips N.V.
    Inventors: Peter VERNICKEL, Christoph LEUSSLER, Ingo SCHMALE, Jochen KEUPP
  • Publication number: 20210072333
    Abstract: The invention relates to a magnetic resonance imaging system (100) for determining an approximation (150) of an electric conductivity distribution within a three-dimensional anatomical structure of interest. The determining comprises acquiring a first set of (3-n)-dimensional magnetic resonance data (144), reconstructing a (3-n)-dimensional phase distribution (146) using the (3-n)-dimensional magnetic resonance data (144), calculating a (3-n)-dimensional electric conductivity distribution (148) using spatial derivatives within the (3-n) dimensions and applying to the (3-n)-dimensional electric conductivity distribution (148) a scaling factor compensating for the relative reduction of dimensions by n.
    Type: Application
    Filed: March 11, 2019
    Publication date: March 11, 2021
    Inventors: Ulrich KATSCHER, Christian FINDELKEE, Jochen KEUPP
  • Publication number: 20210063519
    Abstract: The present disclosure relates to a medical analysis system (111) for processing magnetic resonance imaging, MRI, data (170) from a target volume (208) in a subject (218). The system (111) comprises a memory (107) for storing machine executable instructions; and a processor (103) for controlling the system (111), wherein execution of the machine executable instructions causes the processor (103) to: determine from the MRI data (103) chemical exchange saturation transfer, CEST, voxel values corresponding to a transfer of saturation between a predefined pool of protons and water protons, the pool of protons having a predefined chemical shift; and weight the CEST values in order to distinguish CEST values of fluid-rich tissues (507) from CEST values of solid tissues (505) in the target volume (208), wherein the fluid-rich tissue comprises an amount of fluid higher than a predefined minimum amount of fluid.
    Type: Application
    Filed: January 2, 2019
    Publication date: March 4, 2021
    Inventor: JOCHEN KEUPP
  • Patent number: 10935617
    Abstract: The invention provides for a magnetic resonance imaging system (100) comprising a memory (134) for storing machine executable instructions (140) and pulse sequence commands (142). The pulse sequence commands are configured for controlling the magnetic resonance imaging system according to a DCE Magnetic Resonance Imaging protocol. The magnetic resonance imaging system further comprises a user interface (200) and a processor (130) for controlling the magnetic resonance imaging system.
    Type: Grant
    Filed: November 23, 2017
    Date of Patent: March 2, 2021
    Assignee: Koninklijke Philips N.V.
    Inventors: Jochen Keupp, Jan Jakob Meineke, Karsten Sommer
  • Publication number: 20200348382
    Abstract: The invention provides for a medical imaging system (100, 300). The medical imaging system comprises a processor (104).
    Type: Application
    Filed: January 7, 2019
    Publication date: November 5, 2020
    Inventors: JOCHEN KEUPP, HOLGER EGGERS