Patents by Inventor Jochen Lang

Jochen Lang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 4929643
    Abstract: Compounds of the formula I ##STR1## with R.sup.1 equal to H or (cyclo)alk(en)yl, R.sup.2 equal to H or alkyl, R.sup.3 equal to alkyl, R.sup.4 /R.sup.5 equal to H, alkyl or acyl, and Y equal to H, alkyl, CF.sub.3 or Hal, are described, as are processes for the preparation thereof.They are effective diuretics and antihypertensive agents with a lipid-lowering action.
    Type: Grant
    Filed: May 1, 1989
    Date of Patent: May 29, 1990
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Max Hropot, Ernold Granzer, Bela Kerekjarto
  • Patent number: 4921875
    Abstract: A description is given of the use of amino-substituted benzoic acid derivatives of the formula I ##STR1## in which R.sup.1 and R.sup.2 denote hydrogen, (cyclo)alkyl, unsubstituted or substituted phenyl or naphthyl, or R.sup.1 and R.sup.2 together denote a chain --(CH.sub.2).sub.m -- with m=3 to 6, or together denote a chain --(CH.dbd.CH).sub.n -- with n equal to 2 or 3; R.sup.3 denotes hydrogen, halogen or alkyl; R.sup.4 denotes hydrogen or NO.sub.2 ; R.sup.5 denotes hydrogen or a radical which can be eliminated under physiological conditions; for the preparation of a remedy for diarrhea.
    Type: Grant
    Filed: March 13, 1987
    Date of Patent: May 1, 1990
    Assignees: Hoechst Aktiengesellschaft, Max-Planck-Gesellschaft Zur Forderung Der Wissenschaften
    Inventors: Heinrich C. Englert, Max Hropot, Hans-Jochen Lang, Rainer Greger
  • Patent number: 4871734
    Abstract: Thienoimidazole-toluidines of the formula I ##STR1## in which A represents ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, and R.sup.1 to R.sup.9 have the meanings stated in the description, and a process for their preparation, pharmaceutical compositions containing them, and their use as inhibitors of gastric acid secretion, are described.
    Type: Grant
    Filed: November 20, 1987
    Date of Patent: October 3, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Manfred Rosner, Weidmann, Klaus, Robert Rippel, Andreas W. Herling
  • Patent number: 4849444
    Abstract: Compounds of the formula I ##STR1## with R.sup.1 equal to H or (cyclo)alk(en)yl, R.sup.2 equal to H or alkyl, R.sup.3 equal to alkyl, R.sup.4 /R.sup.5 equal to H, alkyl or acyl, and Y equal to H, alkyl, CF.sub.3 or Hal, are described, as are processes for the preparation thereof.They are effective diuretics and antihypertensive agents with a lipid-lowering action.
    Type: Grant
    Filed: April 22, 1988
    Date of Patent: July 18, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Max Hropot, Ernold Granzer, Bela Kerekjarto
  • Patent number: 4845118
    Abstract: The invention relates to compounds of the formula ##STR1## in which A represents ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, and R.sup.1 to R.sup.9 have the meanings given in the description, to a process for their preparation, to pharmaceutical compositions containing them, and to their use as inhibitors of gastric acid secretion.
    Type: Grant
    Filed: December 22, 1987
    Date of Patent: July 4, 1989
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Robert Rippel, Andreas W. Herling, Klaus Weidmann
  • Patent number: 4661636
    Abstract: Compounds of the formula I ##STR1## where R.sup.1 is hydrogen, lower alkyl, lower alkoxy, amino or dialkylamino; R.sup.2 and R.sup.3 are O-alkyl, N-dialkyl or S-alkyl, or R.sup.2 and R.sup.3 together represent --X--(CH.sub.2).sub.m --X, a carbonyl group or an imino group NR, and m is 2-6; where R.sup.4 is lower alkyl, cycloalkyl, alkenyl or dialkylamino, and where R.sup.5 is lower alkyl or cycloalkyl, and where n is 1 or 2, have excellent cytoprotective effects.They are prepared by reacting compounds II ##STR2## with formaldehyde or a reagent producing formaldehyde.
    Type: Grant
    Filed: September 7, 1984
    Date of Patent: April 28, 1987
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Heinrich C. Englert, Hans-Jochen Lang, Dieter Mania, Martin Bickel
  • Patent number: 4574128
    Abstract: 5-(4-Chloro-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarboxylic acids of the formula I ##STR1## in which R.sup.1 and R.sup.2 are identical or different and represent hydrogen, halogen or methyl, both as racemic mixtures and in the form of their optical isomers, and their physiologically tolerated salts are described, as is their preparation. They are outstanding diuretics and saluretics with an additional uricosuric component.
    Type: Grant
    Filed: May 15, 1984
    Date of Patent: March 4, 1986
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bernhard Seuring, Hans-Jochen Lang, Max Hropot, Roman Muschaweck
  • Patent number: 4421757
    Abstract: Thiazoline derivatives of the formula I ##STR1## wherein R.sup.1 to R.sup.6 and Y have the meanings given, their physiologically tolerated salts, processes for their preparation, pharmaceutical preparations based on these compounds as well as their use as medicaments comprise the invention. In addition, intermediates are described.
    Type: Grant
    Filed: December 28, 1981
    Date of Patent: December 20, 1983
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Bernhard Seuring, Ernold Granzer
  • Patent number: 4346088
    Abstract: Thiazoline derivatives of the general formula I ##STR1## wherein R.sup.1 to R.sup.7 have the specified meanings, physiologically acceptable acid addition salts thereof, processes for their preparation, pharmaceutical preparations based on these compounds and their use for acting on the serum lipoprotein spectrum. The invention moreover relates to compounds of the formulae ##STR2## wherein A, R, R.sup.1 to R.sup.7, Y and Z have the specified meanings.
    Type: Grant
    Filed: July 1, 1980
    Date of Patent: August 24, 1982
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Bernhard Seuring, Ernold Granzer
  • Patent number: 4235918
    Abstract: Benzenesulfonamide derivatives as defined in the specification have an outstanding salidiuretic action. Some of the compounds exhibit a significant increase in the excretion of uric acid and the uric acid clearance. They are distinguished by a long-lasting period of action and are suitable for the treatment of hypertonic conditions in humans, optionally in combination with anti-hypertonic agents.
    Type: Grant
    Filed: August 16, 1978
    Date of Patent: November 25, 1980
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Roman Muschaweck, Max Hropot
  • Patent number: 4174397
    Abstract: Thiazolidine derivatives of the formula I ##STR1## in which the substituents R.sup.1 to R.sup.7 have the meanings as indicated in the following and which have in the free form or in the form of their non toxic acid addition salts valuable pharmaceutical properties, processes for preparing them, pharmaceutical preparations on the basis of these compounds and their use as medicines.
    Type: Grant
    Filed: September 6, 1977
    Date of Patent: November 13, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Bernd Knabe, Hans-Jochen Lang, Ernold Granzer
  • Patent number: 4156732
    Abstract: Heterocyclic sulfamoyl-aryl-ketones wherein the heterocyclic component consists of a benzofuran, indole or benzothiophene radical and the sulfamoyl-aryl moiety is ortho-substituted by halogen, methyl or trifluoromethyl having uricosuric, hypouricemic and salidiuretic action and a process for their manufacture.
    Type: Grant
    Filed: June 20, 1978
    Date of Patent: May 29, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Josef Musil, Roman Muschaweck
  • Patent number: 4156735
    Abstract: 4-(Sulfamoyl-phenyl)-4-hydroxy-2-imino-thiazolidine-derivatives having salidiuretic activity and a process for their manufacture.
    Type: Grant
    Filed: March 13, 1978
    Date of Patent: May 29, 1979
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Roman Muschaweck
  • Patent number: 4129656
    Abstract: 4-(Sulfamoyl-phenyl)-4-hydroxy-thiazolidine-derivatives having salidiuretic activity and a process for their manufacture.
    Type: Grant
    Filed: January 18, 1977
    Date of Patent: December 12, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Roman Muschaweck
  • Patent number: 4125614
    Abstract: The invention relates to thiazolidine derivatives having in 4-position a hydroxy group and a 3'-sulphamyl-phenyl substituent, in 2-position an imino group and in 1-position an aliphatic or cycloaliphatic substituent. Said thiazolidines have diuretic activity.The invention also relates to a process for the manufacture of said compounds.
    Type: Grant
    Filed: April 19, 1977
    Date of Patent: November 14, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Roman Muschaweck
  • Patent number: 4118501
    Abstract: 4-(Sulfamoyl-phenyl)-4-hydroxy-2-imino-thiazolidine-derivatives having salidiuretic activity and a process for their manufacture.
    Type: Grant
    Filed: January 14, 1977
    Date of Patent: October 3, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Roman Muschaweck
  • Patent number: 4083979
    Abstract: Diuretically active thiazolidine compounds and methods for making the same are disclosed, said compounds having an alkyl or alkenyl substituent in the 1-position, an imino group in the 2-position, and an hydroxy group and an N-acylated 3'-sulfamoylphenyl substituent in the 4-position, i.e.
    Type: Grant
    Filed: October 13, 1976
    Date of Patent: April 11, 1978
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Roman Muschaweck
  • Patent number: 4061761
    Abstract: The invention relates to thiazolidine derivatives having in 4-position a hydroxy group and a 3'-sulphamyl-phenyl substituent, in 2-position an imino group and in 1-position an aliphatic or cycloaliphatic substituent. Said thiazolidines have diuretic activity.The invention also relates to a process for the manufacture of said compounds.
    Type: Grant
    Filed: July 25, 1975
    Date of Patent: December 6, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Roman Muschaweck
  • Patent number: 4061647
    Abstract: The invention relates to thiazolidine derivatives having in 4-position a hydroxy group and a 3'-sulphamyl-phenyl substituent the phenyl ring of which is di-substituted by halogen or methyl, in 2 position an imino group and in 1-position an aliphatic or cycloaliphatic substituent. Said thiazolidines have diuretic activity.The invention also relates to a process for the manufacture of said compounds.
    Type: Grant
    Filed: July 27, 1976
    Date of Patent: December 6, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Hans-Jochen Lang, Roman Muschaweck
  • Patent number: 4024274
    Abstract: N-Cycloalkyl-benzylamine derivatives of the formula ##STR1## in which R.sup.1 represents hydrogen or lower alkyl of 1 to 4 carbon atoms, R.sup.2 represents a cycloalkyl radical of a total of 7 to 12 carbon atoms which may be alkyl-substituted and may contain hydrocarbon bridges of 1 to 3 carbon atoms, R.sup.3 represents hydrogen, alkoxy of 1 to 4 carbon atoms, R.sup.4 represents hydrogen or alkoxy of 1 to 4 carbon atoms or halogen, and R.sup.5 represents alkoxy of 1 to 4 carbon atoms, methylene dioxy, ethylene dioxy, benzyloxy or halogen, and the physiologically tolerated salts thereof are disclosed as having diuretic and saluretic activity.
    Type: Grant
    Filed: January 21, 1975
    Date of Patent: May 17, 1977
    Assignee: Hoechst Aktiengesellschaft
    Inventors: Eike Druckrey, Bernd Knabe, Hans-Jochen Lang, Milos Babej, Roman Muschaweck