Patents by Inventor Jochen Muller-Ibeler

Jochen Muller-Ibeler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hydrazide building blocks and hydrazide modified biomolecules
    Patent number: 7129229
    Abstract: This invention relates to attachment chemistries for binding macromolecules to a substrate surface or to other conjugation targets. More particularly, this invention relates to attachment chemistries involving branched or linear structures having one or more hydrazide attachment moieties for binding the macromolecules to a substrate surface, or for other conjugation reactions. Novel modifying reagents are provided for the introduction of protected hydrazide attachment moieties or precursor forms of such hydrazides to the macromolecule, either as a single hydrazide or as multiple hydrazides.
    Type: Grant
    Filed: August 10, 2001
    Date of Patent: October 31, 2006
    Assignee: Nanogen Recognomics GmbH
    Inventors: Stefan Raddatz, Jochen Müller-Ibeler, Markus Schweitzer, Christoph Brücher, Norbert Windhab, John R. Havens, Thomas J. Onofrey, Charles H. Greef, Daguang Wang
  • Sorting and immobilization system for nucleic acids using synthetic binding systems
    Publication number: 20050208576
    Abstract: Methods are provided for producing an array of immobilized nucleic acids on an array device. The array device has a plurality of microlocations each having an electrode. At least one of the microlocations has a synthetic addressing unit coupled to the microlocation. The microlocation is the activated, usually by electronically biasing the electrode of the microlocation. The at least one microlocation is then contacted by a conjugate which has a nucleic acid and a synthetic binding unit. The conjugate is then coupled to the microlocation through an interaction between the synthetic binding unit and the synthetic addressing unit. In one embodiment, the synthetic binding unit and synthetic addressing unit may be pRNA, pDNA, or CNA.
    Type: Application
    Filed: May 17, 2005
    Publication date: September 22, 2005
    Inventors: Markus Schweitzer, Richard Anderson, Michael Fiechtner, Jochen Muller-Ibeler, Stefan Raddatz, Christoph Brucher, Norbert Windhab, Jill Orwick, Eberhard Schneider, Marc Pignot, Stefan Kienle
  • Method for the production of cna
    Publication number: 20040249152
    Abstract: The invention relates to a novel method for the production of CNA oligomers and to artificial supramolecular CNA-p-RNA pairing systems and to the use thereof, especially in biotechnological assays.
    Type: Application
    Filed: July 19, 2004
    Publication date: December 9, 2004
    Inventors: Dieter Reuschling, Jochen Muller-Ibeler, Thomas Wagner, Thomas Krumm, Jochen Wermuth, Marc Pignot
  • Macromolecules having hydrazide attachment moieties and reagents for their production
    Publication number: 20040087807
    Abstract: This invention relates to attachment chemistries for binding macromolecules to a substrate surface or to other conjugation targets. More particularly, this invention relates to attachment chemistries involving branched or linear structures having one or more hydrazide attachment moieties for binding the macromolecules to a substrate surface, or for other conjugation reactions. Novel modifying reagents are provided for the introduction of protected hydrazide attachment moieties or precursor forms of such hydrazides to the macromolecule, either as a single hydrazide or as multiple hydrazides.
    Type: Application
    Filed: August 15, 2003
    Publication date: May 6, 2004
    Inventors: Stefan Raddatz, Jochen Muller-Ibeler, Markus Schweitzer, Christoph Brucher, Norbert Windhab, John r. Havens, Thomas J. Onofrey, Charles H. Greef, Daguang Wang