Abstract: The present invention relates to medical image editing. In order to facilitate the medical image editing process, a medical image editing device (50) is provided that comprises a processor unit (52), an output unit (54), and an interface unit (56). The processor unit (52) is configured to provide a 3D surface model of an anatomical structure of an object of interest. The 3D surface model comprises a plurality of surface sub-portions. The surface sub-portions each comprise a number of vertices, and each vertex is assigned by a ranking value. The processor unit (52) is further configured to identify at least one vertex of vertices adjacent to the determined point of interest as an intended vertex. The identification is based on a function of a detected proximity distance to the point of interest and the assigned ranking value. The output unit (54) is configured to provide a visual presentation of the 3D surface model.

Abstract: There is provided a method and apparatus for adjusting a model of an anatomical structure in a sequence of images of the anatomical structure. The model is placed with respect to the anatomical structure in the sequence of images. A user input is received to adjust the model in a selected image of the sequence, and based on the user input, a part of the model that lies in the selected image and a previously unadjusted part of the model that lies in one or more other images of the sequence is adjusted, whilst fixing in place a previously adjusted part of the model that lies in other images of the sequence.

Abstract: The invention provides for a medical imaging system (100, 300, 400) comprising a memory (110) containing machine executable instructions (120) and a processor (106). Execution of the machine executable instructions cause the processor to: receive (200) a magnetic resonance image (300), receive (202) meta data descriptive of the magnetic resonance image, wherein the metadata comprises reference gray scale value data (124) for two or more tissue types; and segment (204) the magnetic resonance image using an image segmentation algorithm (126) that uses the reference gray scale value data.

Abstract: Systems and methods are provided for generating and using statistical data which is indicative of a difference in shape of a type of anatomical structure between images acquired by a first imaging modality and images acquired by a second imaging modality. This statistical data may then be used to modify a first segmentation of the anatomical structure which is obtained from an image acquired by the first imaging modality so as to predict the shape of the anatomical structure in the second imaging modality, or in general, to generate a second segmentation of the anatomical structure as it may appear in the second imaging modality based on the statistical data and the first segmentation.

Abstract: It is an object of the invention to provide for a system, method and computer program product enabling monitoring of effects of intrafraction motion during the radio therapy treatment. According to a first aspect of the invention this object is achieved by an ultrasound guided radiotherapy system, comprising a radiotherapy system configured for providing a radiation treatment by means of a radiation beam to a treatment target. The ultrasound guided radiotherapy system further comprises an ultrasound imaging system configured for acquiring a 3D online image of the treatment target and/or an organ at risk during the radiation treatment.

Abstract: There is provided a method and apparatus for segmenting two-dimensional images of an anatomical structure. A time sequence of two-dimensional images of the anatomical structure is acquired (202) and a segmentation model for the anatomical structure is acquired (204). The segmentation model comprises a plurality of segments. The acquired segmentation model is applied to the entire time sequence of two-dimensional images of the anatomical structure simultaneously in time and space to segment the time sequence of two-dimensional images by way of the plurality of segments (206).

Abstract: There is provided a method and apparatus for segmenting a two-dimensional image of an anatomical structure. A three-dimensional model of the anatomical structure is acquired (202). The three-dimensional model comprises a plurality of segments. The acquired three-dimensional model is adapted to align the acquired three-dimensional model with the two-dimensional image (204). The two-dimensional image is segmented by the plurality of segments of the adapted three-dimensional model.

Abstract: A system and a method are provided for analyzing an image of an aortic valve structure to enable assessment of aortic valve calcifications. The system comprises an image interface for obtaining an image of an aortic valve structure, the aortic valve structure comprising aortic valve leaflets and an aortic bulbus. The system further comprises a segmentation subsystem for segmenting the aortic valve structure in the image to obtain a segmentation of the aortic valve structure. The system further comprises an identification subsystem for identifying a calcification on the aortic valve leaflets by analyzing the image of the aortic valve structure.

Abstract: A system and method are provided for brain tissue classification, which involves applying an automated tissue classification technique to an image of a brain based on a prior probability map, thereby obtaining a tissue classification map of the brain. A user is enabled to, using a user interaction subsystem, provide user feedback which is indicative of a) an area of misclassification in the tissue classification map and b) a correction of the misclassification. The prior probability map is then adjusted based on the user feedback to obtain an adjusted prior probability map, and the automated tissue classification technique is re-applied to the image based on the adjusted prior probability map. An advantage over a direct correction of the tissue classification map may be that the user does not need to indicate the area of misclassification or the correction of the misclassification with a highest degree of accuracy. Rather, it may suffice to provide an approximate indication thereof.

Abstract: A process for producing a multilayer pipe by expansion is disclosed, with or without heating, in which a multilayer pipe (1) comprises at least one outer pipe of metallic material (10) and an inner pipe of metallic material (20), the inner pipe of metallic material (20) having a yield strength lower than the yield strength of the outer pipe (23) and an external diameter smaller than the internal diameter of the outer pipe. The process for producing the multilayer pipe comprises a mounting step (34) between the pipes (10, 20), wherein the inner pipe is inserted inside the outer pipe, and at least one mechanical expansion step (36), comprising moving a mandrel (2) longitudinally and internally in the inner pipe (20) while the outer pipe and the inner pipe are held at a fixed position, wherein at least part of the mandrel (2) has a greater external diameter than the internal diameter of the inner pipe.

Abstract: A system and method are provided for interactive editing of a mesh which has been applied to a three-dimensional (3D) image to segment an anatomical structure shown therein. To facilitate the interactive editing of the applied mesh, a view of the 3D image is generated which shows a mesh part to be edited, with the view being established based on a local orientation of the mesh part. Advantageously, the view may be generated to be substantially orthogonally to the mesh part, or to a centerline of the anatomical structure which is determined as a function of the mesh part. Accordingly, an orthogonal view is established which facilitates the user in carrying out the editing action with respect to the mesh part. It is therefore not needed for the user to manually navigate through the 3D image to obtain a view which is suitable for mesh editing, which is typically time consuming.

Abstract: It is an object of the invention to provide for an improved radiation treatment. According to a first aspect of the invention, this object is achieved by a method for determining a patient specific locally varying margin on a treatment target and/or an organ at risk in order to compensate for local intrafraction motion expected during a radiotherapy fraction to be delivered over a radiotherapy fraction time interval. The patient specific locally varying margin is determined based on a displacement and/or an estimate of the displacement of at least a first location and a second location on the treatment target and/or organ at risk.

Abstract: The present invention relates to a medical imaging system (10) for planning an implantation of a cardiac implant (42), comprising: a receiving unit (12) for receiving a plurality of three-dimensional (3D) cardiac images (14, 14?) showing different conditions of a heart (32) during a cardiac cycle; a segmentation unit (22) for segmenting within the plurality of 3D cardiac images (14, 14?) a target implant region (38) and a locally adjacent region (40) that could interfere with the cardiac implant (42); a simulation unit (24) for simulating the implantation of the cardiac implant (42) within the target implant region (40) in at least two of the plurality of 3D cardiac images (14, 14?); a collision evaluation unit (26) for evaluating an overlap (46) of the simulated cardiac implant (42) with the segmented locally adjacent region (40) in at least two of the plurality of 3D cardiac images (14, 14?); and a feedback unit (28) for providing feedback information to a user concerning the evaluated overlap (46).

Abstract: Disclosed is a device for filling a receptacle, comprising at least one filling station (48) for filling at least one receptacle (36), and at least one receptacle holder (38) for conveying the receptacle (36) relative to the filling station (48), characterized in that at least one driving surface (13) and at least one mover (20) which can be coupled to the driving surface (13) especially in a magnetic manner are provided, the mover (20) being arranged so as to be movable and/or rotatable on the driving surface (13) in at least two degrees of freedom, and in that the receptacle holder (38) is disposed on the mover (20).

Abstract: The cross-sectional area of a tubular cardiovascular structure to assess blood flow wherein the segmentation of the lumen is applied with a deformable model to the three-dimensional image and fitting the deformable model to the three-dimensional image to obtain a fitted model representing the segmentation of the lumen.

Abstract: A system (100) is provided for performing a model-based segmentation of an anatomical structure in a medical image. The system comprises a processor (140) configured for performing a model-based segmentation of the anatomical structure by applying a deformable model to image data (042). Moreover, definition data (220) is provided which defines a geometric relation between a first part and a second part of the deformable model of which a corresponding first part of the anatomical structure is presumed to be better visible in the image data than a corresponding second part of the anatomical structure. The definition data is then used to adjust a fit of the second part of the deformable model. As a result, a better fit of the second part of the deformable model to the second part of the anatomical structure is obtained despite said part being relatively poorly visible in the image data.

Abstract: A system and method are provided for interactive editing of a mesh which has been applied to a three-dimensional (3D) image to segment an anatomical structure shown therein. To facilitate the interactive editing of the applied mesh, a view of the 3D image is generated which shows a mesh part to be edited, with the view being established based on a local orientation of the mesh part. Advantageously, the view may be generated to be substantially orthogonally to the mesh part, or to a centerline of the anatomical structure which is determined as a function of the mesh part. Accordingly, an orthogonal view is established which facilitates the user in carrying out the editing action with respect to the mesh part. It is therefore not needed for the user to manually navigate through the 3D image to obtain a view which is suitable for mesh editing, which is typically time consuming.

Abstract: It is an object of the invention to provide for a system, method and computer program product enabling monitoring of effects of intrafraction motion during the radio therapy treatment. According to a first aspect of the invention this object is achieved by an ultrasound guided radiotherapy system, comprising a radiotherapy system configured for providing a radiation treatment by means of a radiation beam to a treatment target. The ultrasound guided radiotherapy system further comprises an ultrasound imaging system configured for acquiring a 3D online image of the treatment target and/or an organ at risk during the radiation treatment.

Abstract: A system and method are provided for brain tissue classification, which involves applying an automated tissue classification technique to an image of a brain based on a prior probability map, thereby obtaining a tissue classification map of the brain. A user is enabled to, using a user interaction subsystem, provide user feedback which is indicative of a) an area of misclassification in the tissue classification map and b) a correction of the misclassification. The prior probability map is then adjusted based on the user feedback to obtain an adjusted prior probability map, and the automated tissue classification technique is re-applied to the image based on the adjusted prior probability map. An advantage over a direct correction of the tissue classification map may be that the user does not need to indicate the area of misclassification or the correction of the misclassification with a highest degree of accuracy. Rather, it may suffice to provide an approximate indication thereof.

Abstract: The present invention relates to a medical imaging system (10) for planning an implantation of a cardiac implant (42), comprising: a receiving unit (12) for receiving a plurality of three-dimensional (3D) cardiac images (14, 14?) showing different conditions of a heart (32) during a cardiac cycle; a segmentation unit (22) for segmenting within the plurality of 3D cardiac images (14, 14?) a target implant region (38) and a locally adjacent region (40) that could interfere with the cardiac implant (42); a simulation unit (24) for simulating the implantation of the cardiac implant (42) within the target implant region (40) in at least two of the plurality of 3D cardiac images (14, 14?); a collision evaluation unit (26) for evaluating an overlap (46) of the simulated cardiac implant (42) with the segmented locally adjacent region (40) in at least two of the plurality of 3D cardiac images (14, 14?); and a feedback unit (28) for providing feedback information to a user concerning the evaluated overlap (46).