Abstract: A cartridge for storing an un-labelled tissue to be imaged by an optical imaging system may include: a container to store the un-labelled tissue, and to interface with the optical imaging system; an optical substrate, provided on a bottom surface of the container, through which the optical imaging system is configured to image the un-labelled tissue to generate a virtually-stained histological image of the un-labelled tissue; and a lid, provided on a top surface of the container, including a membrane to compress the un-labelled tissue against the optical substrate such that an entire margin of the un-labelled tissue is flat against the optical substrate.

Abstract: A system for training a machine-learning algorithm includes one or more processors, and one or more storage devices. The system is configured to receive training data. The training data includes microscope images from a surgical microscope obtained during a surgery. The microscope images show tissue. The system is further configured to adjust the machine-learning algorithm based on the training data to obtain a trained machine-learning algorithm, such that the trained machine-learning algorithm corrects marked sections of tissue in a microscope image of the microscope images, and provide the trained machine-learning algorithm.

Abstract: A system for training of a machine-learning algorithm includes one or more processors and one or more storage devices. The system is configured to receive training data. The training data includes images showing a tissue. The system is further configured to adjust the machine-learning algorithm to obtain a trained machine-learning algorithm based on the training data, such that the trained machine-learning algorithm generates instruction data for at least a part of the tissue shown in the images. The instruction data is indicative of an action to be performed on the tissue. The system is further configured to provide the trained machine-learning algorithm.

Abstract: Examples relate to a microscope system, such as a surgical microscope system, and to a corresponding system, method and computer program for a microscope system. The system comprises one or more processors and one or more storage devices. The system is configured to obtain imaging sensor data from at least one optical imaging sensor of a microscope of the microscope system. The system is configured to generate a plurality of different preview images based on the imaging sensor data. The plurality of different preview images are continuously updated. The system is configured to obtain a control input signal from an input device of the microscope system. The system is configured to generate a display signal for a display device of the microscope system. The display signal comprises a user interface showing two or more preview images of the plurality of different preview images with a smaller size and a further image with a larger size.

Abstract: A timer for a surgical imaging device is disclosed. The timer determines a working time of an imaging agent and outputs an indicator for display based on the working time. The working time can be a start time at which a signal from the agent is observable at an imaging site and/or an end time at which the agent is cleared.

Abstract: A microscope, including an x motor, a y motor, and a z axis focusing driving mechanism that drive a stage to move; at least one knob operatively coupled to the x motor or y motor or the z axis focusing driving mechanism selectively via a controller; and at least one button coupled to the controller in communication. The controller is configured to disconnect a normal operative coupling between the knob and the z axis focusing driving mechanism and establish an operative coupling between the knob and the x motor or y motor when receiving a predetermined button signal, and restore the normal operative coupling between the knob and the z axis focusing driving mechanism and disconnect the operative coupling between the knob and the x motor or y motor when no longer receiving the predetermined button signal or when receiving a next button signal.

Abstract: The invention relates to a microscope, comprising a stage (13); an x motor, a y motor, and a z axis focusing driving mechanism that drive the stage to move along left-right, front-rear, and up-down directions respectively; a controller; at least one knob (3) which is operatively coupled to the x motor and/or y motor or the z axis focusing driving mechanism selectively by means of the controller to control operation of the coupled motor or the coupled z axis focusing driving mechanism; and at least one button (4, 5) which is coupled to the controller in communication and sends to the controller a button signal indicating that the button has been triggered by operation of the microscope user.

Abstract: The present invention relates to a method for automatically segmenting a color image composed of pixels having been captured for example using a digital microscope. The method provides for a color to be selected representing a region to be segmented of the color image. The colors assigned to the pixels and the color selected are in accordance with a first color model. A clearance for each of the pixels is determined representing a distance between the selected color and the color of the corresponding pixel. The colors assigned to the pixels and the color selected are in accordance with a perception-oriented second color model. One of the pixels is assigned to the segmented region when the clearance assigned to the corresponding pixel is below a settable threshold value and when the hue assigned to the corresponding pixel is within a settable interval around the hue assigned to the selected color.

Abstract: The present invention relates to a method for automatically segmenting a color image composed of pixels having been captured for example using a digital microscope. The method provides for a color to be selected representing a region to be segmented of the color image. The colors assigned to the pixels and the color selected are in accordance with a first color model. A clearance for each of the pixels is determined representing a distance between the selected color and the color of the corresponding pixel. The colors assigned to the pixels and the color selected are in accordance with a perception-oriented second color model. One of the pixels is assigned to the segmented region when the clearance assigned to the corresponding pixel is below a settable threshold value and when the hue assigned to the corresponding pixel is within a settable interval around the hue assigned to the selected color.

Abstract: Leisure equipment is disclosed which permits an experience of fully controlled loop-the-loop rotary motion with a wheeled vehicle. The leisure equipment comprises a frame structure with a trough-shaped wheel track, an axis of rotation and at least one rotating arm with one wheeled vehicle each. The trough-shaped wheel track is curved so as to form a closed contour. The axis of rotation is contained within this contour. At least one rotating arm is rotatably supported on this axis of rotation. At the rotating arm a wheeled vehicle is fastened which is adapted to be guided in the wheel track. The wheeled vehicle is pressed into the wheel track by a pressing device acting on the rotating arm. In this way a contact of wheel track and wheeled vehicle exists in every point of the wheel track. With the wheeled vehicle of the leisure equipment, a rider can perform loop-the-loop rotary motions or revolutions during which he retains full command of the motion at all times.

Abstract: A vehicle in the form of a bicycle with a crankset drive, which is in active frictioned gripping or positive connection with a strand extending substantially vertically. The bicycle according to the invention is therefore capable of riding along the vertical strand.