Patents by Inventor Jochen Wiesner

Jochen Wiesner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10266842
    Abstract: The present invention discloses polypeptides comprising an amino acid sequence being identical with at least 12 contiguous amino acid residues of SEQ ID No 2. The polypeptides according to the invention are effective against fungi, especially against fungi causing plant diseases, and against fungi colonizing agricultural products. The invention further discloses processes for preparing such polypeptides, and nucleic acids coding for such polypeptides. In addition, the invention relates to processes and preparations for treating plants using the polypeptides according to the invention, and to the use of the nucleic acids according to the invention for producing crops that are protected against damage from fungi.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: April 23, 2019
    Assignee: Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V.
    Inventors: Andreas Vilcinskas, Anne-Kathrin Poeppel, Jochen Wiesner
  • Publication number: 20160002663
    Abstract: The present invention discloses polypeptides comprising an amino acid sequence being identical with at least 12 contiguous amino acid residues of SEQ ID No 2. The polypeptides according to the invention are effective against fungi, especially against fungi causing plant diseases, and against fungi colonizing agricultural products. The invention further discloses processes for preparing such polypeptides, and nucleic acids coding for such polypeptides. In addition, the invention relates to processes and preparations for treating plants using the polypeptides according to the invention, and to the use of the nucleic acids according to the invention for producing crops that are protected against damage from fungi.
    Type: Application
    Filed: January 23, 2014
    Publication date: January 7, 2016
    Inventors: Andreas VILCINSKAS, Anne-Kathrin PÖPPEL, Jochen WIESNER
  • Publication number: 20150190418
    Abstract: The invention relates to pharmaceutical combination preparations for use in the therapeutical and prophylactic treatment of bacterial and parasitic infections, especially malaria. The inventive preparations contain as the active substances 3-N-formyl-hydroxylaminopropyl phosphonic acid derivatives or 3-N-acetylhydroxylaminopropyl phosphonic acid derivatives combined with other pharmaceutical active agents.
    Type: Application
    Filed: March 16, 2015
    Publication date: July 9, 2015
    Applicant: Jomaa Pharmaka GmbH
    Inventors: Hassan Jomaa, Jochen Wiesner
  • Publication number: 20140303060
    Abstract: A process for degrading a biofilm on surfaces of objects by means of an extract of a bacterium of the genus Lysobacter, whereby the extract is obtainable by a process comprising the following steps: culturing Lysobacter on a solid or in a liquid medium; incubating at a temperature of 20° C. to 40° C. for a duration of from 1 to 15 days; extraction of at least one component, which is able to degrade a biofilm; optionally followed by further purification steps, such as ion-exchange chromatography and/or concentration.
    Type: Application
    Filed: December 13, 2012
    Publication date: October 9, 2014
    Applicant: Fraunhofer Gesellschaft Zur Foerderung der angewan Forschung E.V.
    Inventors: Anke Goekcen, Jochen Wiesner, Andreas Vilcinskas, Rainer Fischer
  • Publication number: 20110112054
    Abstract: The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
    Type: Application
    Filed: January 17, 2011
    Publication date: May 12, 2011
    Applicant: BIOAGENCY AG
    Inventors: Hassan Jomaa, Matthias Eberl, Boran Altincicek, Martin Hintz, Oliver Wolf, Ann-Kristin Kollas, Armin Reichenberg, Jochen Wiesner
  • Patent number: 7871992
    Abstract: The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
    Type: Grant
    Filed: June 11, 2008
    Date of Patent: January 18, 2011
    Assignee: Bioagency AG
    Inventors: Hassan Jomaa, Oliver Wolf, Boran Altincicek, Mathias Eberl, Martin Hintz, Ann-Kristin Kollas, Armin Reichenberg, Jochen Wiesner
  • Patent number: 7638505
    Abstract: The present invention relates to novel phosphonic acid compounds having the structural formula (I): wherein: (a) R is a group of 1 to 5 substituents independently selected from the group consisting of fluoro, chloro, bromo, C1-4 alkoxy, C1-4 alkyl, hydroxy, formyl, trifluoromethoxy, phenyl, heterocyclic, heterocyclic-substituted methyl, aminomethyl, hydroxy methyl, bromomethyl, sulfonyl chloride, acetyl chloride, nitroso and cyano, (b) R1 is selected from the group consisting of hydrogen, C1-7 alkyl, C3-10 cycloalkyl, aryl, arylalkyl and heterocyclic, and (c) R2 is selected from the group consisting of hydroxy and hydroxy-protecting groups, and stereoisomer, solvates and salts thereof. These compounds are useful as anti-infectious and anti-parasitic agents, in particular anti-malaria agents.
    Type: Grant
    Filed: December 22, 2006
    Date of Patent: December 29, 2009
    Assignee: Universiteit Gent
    Inventors: Serge Van Calenbergh, Timothy Haemers, Vincent Devreux, Hassan Jomaa, Jochen Wiesner
  • Publication number: 20080312190
    Abstract: The present invention relates to novel phosphonic acid compounds having the structural formula (I): wherein: (a) R is a group of 1 to 5 substituents independently selected from the group consisting of fluoro, chloro, bromo, C1-4 alkoxy, C1-4 alkyl, hydroxy, formyl, trifluoromethoxy, phenyl, heterocyclic, heterocyclic-substituted methyl, aminomethyl, hydroxy methyl, bromomethyl, sulfonyl chloride, acetyl chloride, nitroso and cyano, (b) R1 is selected from the group consisting of hydrogen, C1-7 alkyl, C3-10 cycloalkyl, aryl, arylalkyl and heterocyclic, and (c) R2 is selected from the group consisting of hydroxy and hydroxy-protecting groups, and stereoisomer, solvates and salts thereof. These compounds are useful as anti-infectious and anti-parasitic agents, in particular anti-malaria agents.
    Type: Application
    Filed: December 22, 2006
    Publication date: December 18, 2008
    Applicant: UNIVERSITEIT GENT
    Inventors: Serge Van Calenbergh, Timothy Haemers, Vincent Devreux, Hassan Jomaa, Jochen Wiesner
  • Publication number: 20080249067
    Abstract: The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
    Type: Application
    Filed: June 11, 2008
    Publication date: October 9, 2008
    Applicant: Bioagency AG
    Inventors: Hassan Jomaa, Matthias Eberl, Boran Altincicek, Martin Hintz, Oliver Wolf, Ann-Kristin Kollas, Armin Reichenberg, Jochen Wiesner
  • Patent number: 7399756
    Abstract: The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
    Type: Grant
    Filed: July 18, 2002
    Date of Patent: July 15, 2008
    Assignee: Bioagency AG
    Inventors: Hassan Jomaa, Matthias Eberl, Boran Altincicek, Martin Hintz, Oliver Wolf, Ann-Kristin Kollas, Armin Reichenberg, Jochen Wiesner
  • Publication number: 20060030546
    Abstract: The present invention describes organophosphorus compounds of general formula (I) their preparation and their uses in the activation of gamma/delta T-cells, in the screening of GcpE and LytB enzyme inhibitors and in the prophylaxis and treatment of diseases in humans and animals.
    Type: Application
    Filed: July 18, 2002
    Publication date: February 9, 2006
    Applicant: Innate Pharma
    Inventors: Hassan Jomaa, Matthias Eberl, Boran Altincicek, Martin Hintz, Oliver Wolf, Ann-Kristin Kollas, Armin Reichenberg, Jochen Wiesner
  • Publication number: 20040235784
    Abstract: Disclosed are pharmaceutical preparations for use in the therapeutical and prophylactic treatment of bacterial and parasitic infections, especially malaria. The preparations contain as active substances 3-N-formyl-hydroxylaminopropyl phosphonic acid derivatives or 3-N-acetylhydroxylaminopropyl phosphonic acid derivatives and may be combined with other pharmaceutical active agents and/or other pharmaceutically acceptable excipients. Also disclosed are methods of treatments using such preparations.
    Type: Application
    Filed: October 1, 2003
    Publication date: November 25, 2004
    Inventors: Hassan Jomaa, Jochen Wiesner
  • Publication number: 20030036532
    Abstract: The invention relates to the use of compounds of formula (I), wherein n=0-3; R1, R2=H, alkyl, aryl, heteroaryl, acyl; R3=H, halogen, alkyl, aryl, heteroaryl, arylalkyl, acyl, CN, NO2, R4—X—; R4=H, alkyl, aryl, heteroaryl, aralkyl, acyl; X=NH, O, S, SO2, NHSO2, OSO2, and A, B, C=organic groups. The inventive compounds are used for the prophylaxis and the therapeutic treatment of infectious processes, especially of infectious processes caused by parasites. The invention further relates to medicaments that contain the inventive compounds.
    Type: Application
    Filed: August 23, 2002
    Publication date: February 20, 2003
    Inventors: Hassan Jomaa, Martin Schlitzer, Jochen Wiesner
  • Patent number: 6114393
    Abstract: Inhibitors of the sodium-hydrogen exchanger are suitable on their own or in combination with other classes of active compound for the production of a medicament for the treament of diseases which are caused by protozoa; thus of diseases which are caused by animal- and human-pathogenic protozoa, such as by intracellularly active parasites of the classes Apicomplexa and Zoomastigophorea, in particular trypanosomes, plasmodia (malaria pathogens), leishmanias, babesias and theilerias, cryptosporidiidae, sarcocystidae, amoebae, coccidia and trichomonads.
    Type: Grant
    Filed: August 26, 1998
    Date of Patent: September 5, 2000
    Assignee: Hoechst Marion Roussel Deutschland GmbH
    Inventors: Hans Jochen Lang, Michael Lanzer, Jochen Wiesner, Cecilia Sanchez, Stefan Wunsch