Abstract: Disclosed is an optical cylinder of a corneal prosthesis comprising: a) an optical cylinder comprising a solid polymer, and b) a plurality of nanoparticles forming a substantially uniform layer on a circumference of the solid polymer surface of the optical cylinder. Also disclosed are methods of surface treatment of optical cylinders of corneal prostheses, and corneal prostheses thereof.

Abstract: Disclosed is an optical cylinder of a corneal prosthesis comprising: a) an optical cylinder comprising a solid polymer, and b) a plurality of nanoparticles forming a substantially uniform layer on a circumference of the solid polymer surface of the optical cylinder. Also disclosed are methods of surface treatment of optical cylinders of corneal prostheses, and corneal prostheses thereof.

Abstract: An optical coherence tomography system and method. The system comprises a detector for detecting an optical coherence tomography signals from a sample; a processing unit for converting the detected signals to raw data; a compensation unit for performing compensation to generate compensated data; and a display for displaying at least the compensated data.

Abstract: The invention relates to a dual-media approach for culturing isolated corneal endothelial cells. Isolated corneal endothelial cells are first contacted with a proliferative medium to propagate and/or expand the endothelial cells followed by a maintenance medium to preserve the morphology and/or characteristics of the corneal endothelial cells. The invention includes the proliferative medium and the maintenance medium and also a combination of the two medium.

Abstract: The present invention relates to corneal stromal keratocytes (CSKs) culture. In particular the present invention relates to a method for culturing corneal stromal keratocytes ex vivo. The method utilises a dual culture medium protocol. In the presence of serum (in particular low serum concentration) in a first culture medium A, the “activated keratocytes” are expandable while specific CSK gene expression is maintained in serum-free ERI condition in a second culture medium B. The invention also relates to culture medium A and B which is supplemented with liquid amnion extract or other additional supplements. This protocol also applied to CSK from other species. Additionally, the present invention provides method for CSK cultivation to provide sufficient quantity of genuine CSKs for corneal tissue engineering without a risk of fibroblastic changes.

Abstract: The invention relates to a dual-media approach for culturing isolated corneal endothelial cells. Isolated corneal endothelial cells are first contacted with a proliferative medium to propagate and/or expand the endothelial cells followed by a maintenance medium to preserve the morphology and/or characteristics of the corneal endothelial cells. The invention includes the proliferative medium and the maintenance medium and also a combination of the two medium.

Abstract: DMEK surgery is performed using a carrier mat made of a polymeric material having elastic memory and a hydrophilic surface, for supporting the descemet's membrane and transporting it to an insertion capsule.