Patents by Inventor Jodie T. Mangor

Jodie T. Mangor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GP64-null baculoviruses pseudotyped with heterologous envelope proteins for gene therapy
    Patent number: 6858205
    Abstract: A pseudotyped baculovirus comprises a deletion, inactivation or reduction from regulation of a baculovirus envelope protein gene, and is engineered to express an envelope protein from another virus or cell, or another protein or molecule that facilitates entry of the baculovirus into a non-host cell, or provided with a heterologous envelope protein or another protein or molecule that facilitates entry of the baculovirus into a non-host cell by other suitable means. Such baculoviruses can be used to efficiently deliver genes to mammalian cells or organisms, and such genes can be expressed either from the baculovirus genome, or integrated into the mammalian cell genome, and can be used for expression of proteins such that purification of secreted or other protein products does not require removal of contaminating baculovirus particles or baculovirus envelope proteins.
    Type: Grant
    Filed: June 20, 2003
    Date of Patent: February 22, 2005
    Assignee: Boyce Thompson Institute for Plant Research
    Inventors: Gary W. Blissard, Jodie T. Mangor, Scott A. Monsma
  • GP64-null baculoviruses pseudotyped with heterologous envelope proteins for gene therapy
    Publication number: 20040009153
    Abstract: A pseudotyped baculovirus comprises a deletion, inactivation or reduction from regulation of a baculovirus envelope protein gene, and is engineered to express an envelope protein from another virus or cell, or another protein or molecule that facilitates entry of the baculovirus into a non-host cell, or provided with a heterologous envelope protein or another protein or molecule that facilitates entry of the baculovirus into a non-host cell by other suitable means. Such baculoviruses can be used to efficiently deliver genes to mammalian cells or organisms, and such genes can be expressed either from the baculovirus genome, or integrated into the mammalian cell genome, and can be used for expression of proteins such that purification of secreted or other protein products does not require removal of contaminating baculovirus particles or baculovirus envelope proteins.
    Type: Application
    Filed: June 20, 2003
    Publication date: January 15, 2004
    Applicant: Boyce Thompson Institute for Plant Research
    Inventors: Gary W. Blissard, Jodie T. Mangor, Scott A. Monsma
  • GP64-null baculoviruses pseudotyped with heterologous envelope proteins
    Patent number: 6607912
    Abstract: A pseudotyped baculovirus comprises a deletion, inactivation or reduction from regulation of a baculovirus envelope protein gene, and is engineered to express an envelope protein from another virus or cell, or another protein or molecule that facilitates entry of said baculovirus into a non-host cell, or provided with a heterologous envelope protein or another protein or molecule that facilitates entry of said baculovirus into a non-host cell by other suitable means. Such baculoviruses can be used to efficiently deliver genes to mammalian cells or organisms, and such genes can be expressed either from the baculovirus genome, or integrated into the mammalian cell genome, and can be used for expression of proteins such that purification of secreted or other protein products does not require removal of contaminating baculovirus particles or baculovirus envelope proteins.
    Type: Grant
    Filed: August 9, 2001
    Date of Patent: August 19, 2003
    Assignee: Boyce Thompson Institute for Plant Research, Inc.
    Inventors: Gary W. Blissard, Jodie T. Mangor, Scott A. Monsma
  • GP64-null baculoviruses pseudotyped with heterologous envelope proteins
    Publication number: 20020115188
    Abstract: A pseudotyped baculovirus comprises a deletion, inactivation or reduction from regulation of a baculovirus envelope protein gene, and is engineered to express an envelope protein from another virus or cell, or another protein or molecule that facilitates entry of said baculovirus into a non-host cell, or provided with a heterologous envelope protein or another protein or molecule that facilitates entry of said baculovirus into a non-host cell by other suitable means. Such baculoviruses can be used to efficiently deliver genes to mammalian cells or organisms, and such genes can be expressed either from the baculovirus genome, or integrated into the mammalian cell genome, and can be used for expression of proteins such that purification of secreted or other protein products does not require removal of contaminating baculovirus particles or baculovirus envelope proteins.
    Type: Application
    Filed: August 9, 2001
    Publication date: August 22, 2002
    Inventors: Gary W. Blissard, Jodie T. Mangor, Scott A. Monsma