Patents by Inventor Joe B. Perales

Joe B. Perales has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Synthetic process and intermediates
    Patent number: 11512088
    Abstract: The present disclosure describes a synthetic process and novel intermediates related to spirocyclic azetidenyl-isobenzofuran derivatives having an isothiazoline moiety, which are useful as antiparasitics.
    Type: Grant
    Filed: January 29, 2020
    Date of Patent: November 29, 2022
    Assignee: AVISTA PHARMA SOLUTIONS, INC.
    Inventors: Jason D. Speake, Joe B. Perales, Brent Christopher Beck, Bharathi Pandi
  • Process for the preparation of rucaparib and novel synthesis intermediates
    Patent number: 11220507
    Abstract: The present invention relates to a process for the preparation of rucaparib; the invention also refers to novel intermediates of synthesis as well as their use in the preparation of i.a. rucaparib.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: January 11, 2022
    Assignee: Advitech Advisory and Technologies SA
    Inventors: Brent Christopher Beck, Joe B. Perales, Jason D. Speake, Ilaria Ferrando
  • PROCESS FOR THE PREPARATION OF RUCAPARIB AND NOVEL SYNTHESIS INTERMEDIATES
    Publication number: 20200331916
    Abstract: The present invention relates to a process for the preparation of rucaparib; the invention also refers to novel intermediates of synthesis as well as their use in the preparation of i.a. rucaparib.
    Type: Application
    Filed: December 15, 2017
    Publication date: October 22, 2020
    Inventors: BRENT CHRISTOPHER BECK, JOE B. PERALES, JASON D. SPEAKE, ILARIA FERRANDO
  • Single enantiomer antiparasitic compounds
    Patent number: 10807992
    Abstract: The present invention relates to single enantiomer isothiazoline compounds of formula (I): and methods of synthesizing the compounds. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Grant
    Filed: November 15, 2018
    Date of Patent: October 20, 2020
    Assignee: Avista Pharma Solutions, Inc.
    Inventors: Jason D. Speake, Bakela Nare, Joe B. Perales, Keqiang Li, Cisco Bee, Jeffrey A. Adams, Kurt S. Van Horn, Brian H. Heasley
  • Antiparasitic compounds
    Patent number: 10772331
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Grant
    Filed: May 23, 2019
    Date of Patent: September 15, 2020
    Assignee: Avista Pharma Solutions, Inc.
    Inventors: Jason D. Speake, Joe B. Perales, Weiming Fan, Solene Clarisse Rolland
  • Sulfonamide derivatives as JAK inhibitors
    Patent number: 10744136
    Abstract: The present invention describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus Kinase inhibitors and are useful in the treatment or control of pruritus, associated with allergic dermatitis, atopic dermatitis in animals, and other disorders and indications where immunosuppression/immunomodulation would be desirable. Also described herein are methods of treating pruritus and atopic dermatitis by administering the compounds of the invention, which are JAK 1 inhibitors.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: August 18, 2020
    Assignee: Avista Pharma Solutions, Inc.
    Inventors: Jason D. Speake, Bharathi Pandi, Joe B. Perales, Weiming Fan
  • Synthetic Process and Novel Intermediates
    Publication number: 20200239481
    Abstract: The present disclosure describes a synthetic process and novel intermediates related to spirocyclic azetidenyl-isobenzofuran derivatives having an isothiazoline moiety, which are useful as antiparasitics.
    Type: Application
    Filed: January 29, 2020
    Publication date: July 30, 2020
    Inventors: Jason D. Speake, Joe B. PERALES, Brent Christopher BECK, Bharathi PANDI
  • Chemical Compounds
    Publication number: 20200138811
    Abstract: The present invention describes novel compounds, or their pharmaceutically acceptable salts, pharmaceutical compositions containing them, and their medical uses. The compounds of the invention have activity as Janus Kinase inhibitors and are useful in the treatment or control of pruritus, associated with allergic dermatitis, atopic dermatitis in animals, and other disorders and indications where immunosuppression/immunomodulation would be desirable. Also described herein are methods of treating pruritus and atopic dermatitis by administering the compounds of the invention, which are JAK 1 inhibitors.
    Type: Application
    Filed: November 4, 2019
    Publication date: May 7, 2020
    Inventors: Jason D. SPEAKE, Bharathi PANDI, Joe B. PERALES, Weiming FAN
  • Synthetic process and intermediates
    Patent number: 10556909
    Abstract: The present disclosure describes a synthetic process and novel intermediates related to spirocyclic azetidenyl-isobenzofuran derivatives having an isothiazoline moiety, which are useful as antiparasitics.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: February 11, 2020
    Assignee: Avista Pharma Solutions, Inc.
    Inventors: Jason D. Speake, Bharathi Pandi, Cyprian O. Ogbu, Jeffrey A. Adams, Joseph A. Moore, III, Joe B. Perales, Keqiang Li
  • Synthetic Process and Novel Intermediates
    Publication number: 20190284199
    Abstract: The present disclosure describes a synthetic process and novel intermediates related to spirocyclic azetidenyl-isobenzofuran derivatives having an isothiazoline moiety, which are useful as antiparasitics.
    Type: Application
    Filed: May 17, 2017
    Publication date: September 19, 2019
    Inventors: Jason D Speake, Bharathi Pandi, Cyprian O. Ogbu, Jeffrey A. Adams, Joseph A. Moore, III, Joe B. Perales, Keqiang Li
  • ANTIPARASITIC COMPOUNDS
    Publication number: 20190274305
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Application
    Filed: May 23, 2019
    Publication date: September 12, 2019
    Inventors: Jason D. Speake, Joe B. Perales, Weiming Fan, Solene Clarisse Rolland
  • Antiparasitic compounds
    Patent number: 10342234
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: July 9, 2019
    Assignee: Avista Pharma Solutions, Inc.
    Inventors: Jason D. Speake, Joe B. Perales, Weiming Fan, Solene Clarisse Rolland
  • SINGLE ENANTIOMER ANTIPARASITIC COMPOUNDS
    Publication number: 20190152983
    Abstract: The present invention relates to single enantiomer isothiazoline compounds of formula (I) and methods of synthesizing the compounds. The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Application
    Filed: November 15, 2018
    Publication date: May 23, 2019
    Inventors: Jason D. Speake, Bakela Nare, Joe B. Perales, Keqiang Li, Cisco Bee, Jeffrey A. Adams, Kurt S. Van Horn, Brian H. Heasley
  • Antiparasitic Compounds
    Publication number: 20190000085
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Application
    Filed: September 6, 2018
    Publication date: January 3, 2019
    Inventors: Jason D. Speake, Joe B. Perales, Weiming Fan, Solene Clarisse Rolland
  • Antiparasitic compounds
    Patent number: 10092001
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: October 9, 2018
    Assignee: Avista Pharma Solutions, Inc.
    Inventors: Jason D. Speake, Joe B. Perales, Weiming Fan, Solene Clarisse Rolland
  • ANTIPARASITIC COMPOUNDS
    Publication number: 20180116223
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Application
    Filed: December 21, 2017
    Publication date: May 3, 2018
    Inventors: Jason D. SPEAKE, Joe B. PERALES, Weiming FAN, Solene Clarisse ROLLAND
  • Antiparasitic compounds
    Patent number: 9883674
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Grant
    Filed: May 24, 2017
    Date of Patent: February 6, 2018
    Assignee: Avista Pharma Solutions, Inc.
    Inventors: Jason D. Speake, Joe B. Perales, Weiming Fan, Solene Clarisse Rolland
  • ANTIPARASITIC COMPOUNDS
    Publication number: 20170258089
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Application
    Filed: May 24, 2017
    Publication date: September 14, 2017
    Inventors: Jason D. Speake, Joe B. PERALES, Weiming FAN, Solene Clarisse ROLLAND
  • Antiparasitic compounds
    Patent number: 9686991
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: June 27, 2017
    Assignee: Avista Pharma Solutions, Inc.
    Inventors: Jason D. Speake, Joe B. Perales, Weiming Fan, Solène Clarisse Rolland
  • ANTIPARASITIC COMPOUNDS
    Publication number: 20160324156
    Abstract: The present invention relates to isothiazoline compounds of formula (I). The compounds are useful for combating or controlling invertebrate pests, in particular arthropod pests and nematodes. The invention also relates to a method for controlling invertebrate pests by using these compounds and to veterinary compositions comprising said compounds.
    Type: Application
    Filed: July 15, 2016
    Publication date: November 10, 2016
    Inventors: Jason D. SPEAKE, Joe B. PERALES, Weiming FAN, Solène Clarisse ROLLAND